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Chronic fatigue: electromyographic & neuropathological evaluation

  [ 112 votes ]   [ Discuss This Article ]
www.ProHealth.com • July 3, 1993


Single fibre electromyography of extensor digitorum communis muscle
(EDC) was performed on 35 patients with chronic fatigue, the
majority of whom also had creatine kinase estimation and
biopsy of EDC. The subjects were categorised as having an
acute-onset post-viral fatigue syndrome, a non-specific
chronic fatigue or possible muscle disease in view of
pronounced myalgia. Of 11 subjects who had myalgia as a
significant symptom, abnormalities in fibre density were found
in 6, and 5 of these had some non-specific abnormalities on
muscle biopsy, with creatine kinase levels being normal in all
cases. Fibre density estimation may be a useful way of
identifying a subgroup of chronic fatigue sufferers with a
possible primary muscle disorder.

Connolly S, Smith DG, Doyle D, Fowler CJ




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