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International Study of Drug to Control Osteoarthritis Progression Recruiting Now

  [ 252 votes ]   [ 1 Comment ]
www.ProHealth.com • May 2, 2008


71 centers in 10 countries & Canadian provinces are now recruiting female subjects with knee osteoarthritis, also known as ‘degenerative joint disease,’ for a 2-year Phase II study.

Target enrollment is 1,400. (An estimated 80% of the population has evidence of OA by age 65. It accounts for 25% of all primary care physician visits and half of all non-steroidal anti-inflammatory drug prescriptions in the U.S.)

This placebo-controlled study (ClinicalTrials.gov # NCT00565812) is sponsored by Pfizer. It will involve the drug code named SD-6010 – designed to inhibit the activity of inducible nitric oxide synthase (iNOS), a ‘signal’ enzyme in the body involved in local immune reaction/inflammation and tissue destruction in joints.

For more information about the trial, the outcome measures and inclusion requirements, and to contact a study center near you for further questions, see the trial listing at ClinicalTrials.gov.




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"New" OA Drug Trials, substance SD-6010
Posted by: leaknits
May 7, 2008
Went looking to find what's in this release from Pfizer, that lovely company which produced Lyrica and claimed it helped with pain-masking...and was mostly wrong in so claiming. By golly, there's a Click Here, I can go see what I want to find. WRONG. Got an advisory that info re SD-6010 is not available under the "Lite" version. Bit the bullet, went to "Advanced." Nothing understandable there, either. Figures. Side note...it never surprises me that "trials" constructed under the "Let's Try This" school of medicine are hundreds or thousands of miles away from where I sit here in Northern California. Do the heads of Pfizer think that OA occurs only in knees? I got news for Pfizer. Omnigusted.
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