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Abstract: The promise of N-methyl-D-aspartate receptor antagonists in fibromyalgia

  [ 28 votes ]   [ Discuss This Article ]
www.ProHealth.com • July 22, 2002


Rheum Dis Clin North Am 2002 May;28(2):343-51  Henriksson KG, Sorensen J.  Department of Rehabilitation Medicine, Faculty of Health Sciences, Linkoping University, Pain Clinic, University Hospital, Linkoping S-581 85, Sweden. mailto:karl-g@telia.com  PMID: 12122922

There is strong evidence that intravenous administration of ketamine following a standardized protocol could be used as a diagnostic test for a central sensitization in the central nervous system in patients with FM.

The combination of a weak opioid and an NMDA-receptor antagonist with few side effects is presently a promise for treatment of pain in a subgroup of patients with FM. The response to intravenously administered ketamine may help select patients for this treatment modality.

Source: Co-Cure




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