ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

16 Tips from 16 Years Sick

Fibromyalgia Fare Fit for All Seasons

New Study Shows Artificial Sweeteners Lead to Diabetes

Essential Oils — An Effective and Healthy Option to Treat Headaches

Higher vitamin D levels associated with less severe disease in NAFLD patients

Krill Oil: Make This Omega-3 Supplement Part of Your Health Regimen

How zinc helps fight esophageal cancer

Everything You Need to Know About Black Cohosh

Low vitamin D levels predict ED in diabetics

The Cellular Enzyme That Promotes Longevity And Reduces Fat Storage

 
Print Page
Email Article

New Research Shows New Arthritis Drugs Cost More but Provide Similar Pain Relief

  [ 17 votes ]   [ Discuss This Article ]
www.ProHealth.com • January 2, 2002




A new study conducted by RxIntelligence, a non-profit research organization founded by the Blue Cross and Blue Shield Association, examined Rofecoxib (Vioxx®) and celecoxib (Celebrex®) in comparison to non- steroidal anti-inflammatory drugs (NSAIDs)such as Motrin (ibuprofen) and Naprosyn (naproxen). The review was presented at the European International Society for Pharmaceutical Outcomes Research meeting in Cannes, France.

RxIntelligence's analysis did not find significant differences in pain reduction in a systematic literature review and meta-analysis of 36 clinical trials. Celecoxib and rofecoxib are part of a class of drugs called selective COX-2 inhibitors. COX-2 inhibitors frequently are prescribed to patients who have experienced side effects, specifically gastric ulcers from using NSAIDs for pain relief.

The study revealed that patients treated with rofecoxib or celecoxib were at lower risk for gastric ulcers during the first year of treatment than patients treated with traditional drugs. They reduced the risk of ulcer complications requiring hospital care from 1.5 percent to less than 1 percent of patients. However, the total number of side effects was comparable, although patients treated with rofecoxib (25 mg/day) were more likely to experience hypertension than those treated with traditional drugs.

"While direct-to-consumer advertising implies that some new drugs are better than existing therapies, this study shows COX-2 inhibitors are about the same at treating the symptoms of osteoarthritis or rheumatoid arthritis," said Michael O. Fleming, M.D., RxIntelligence board chairman. "They do substantially lower the risk of ulcers in arthritis patients. But for people who are not at risk of ulcers, the older, less costly drugs provide the same pain relief at lower cost."

In an economic evaluation, treatment costs for selective COX-2 inhibitors were found to be substantially higher than for the traditional NSAIDs, but may still be appropriate for patients with two or more risk factors for gastric ulcers such as age, history of GI ulcers, or use of cortisone. The economic analysis showed that in these specific cases it is more cost-effective to use selective COX-2 inhibitors alone than to use a combination of non-selective NSAIDs with other drugs protecting for ulcers (misoprostol or proton pump inhibitors).



Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Energy NADH™ 12.5mg Ultra ATP+, Double Strength


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

"It's Not Easy Being Green" - But It Is Healthy
Could a B-12 Deficiency Be Causing Your Symptoms? Could a B-12 Deficiency Be Causing Your Symptoms?
Optimize Your Immune System Naturally: Thymic Protein A Optimize Your Immune System Naturally: Thymic Protein A
The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS
Vitamin E: Super Antioxidant We Only Thought We Knew Vitamin E: Super Antioxidant We Only Thought We Knew

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map