ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

SURVEY RESULTS: Cognitive Impairment II

Fighting Heartburn and Gerd Naturally – And Safely!

Vital Molecule Increases Cellular Energy and Improves Cognitive Function

Top Vitamin and Mineral Deficiencies — Are You at Risk?

Trimming the spare tire: Canola oil may cut belly fat

How Pomegranate May Protect Against Cancer

Omega Fix for Obesity: How the Right Fats Fight Fat

Curcumin Reverses the Cellular Damage of Chronic Stress

Probiotics improve cognition in Alzheimer's patients

The Onion: Cancer Fighter and Food Preserver

 
Print Page
Email Article

New Research Shows New Arthritis Drugs Cost More but Provide Similar Pain Relief

  [ 17 votes ]   [ Discuss This Article ]
www.ProHealth.com • January 2, 2002




A new study conducted by RxIntelligence, a non-profit research organization founded by the Blue Cross and Blue Shield Association, examined Rofecoxib (Vioxx®) and celecoxib (Celebrex®) in comparison to non- steroidal anti-inflammatory drugs (NSAIDs)such as Motrin (ibuprofen) and Naprosyn (naproxen). The review was presented at the European International Society for Pharmaceutical Outcomes Research meeting in Cannes, France.

RxIntelligence's analysis did not find significant differences in pain reduction in a systematic literature review and meta-analysis of 36 clinical trials. Celecoxib and rofecoxib are part of a class of drugs called selective COX-2 inhibitors. COX-2 inhibitors frequently are prescribed to patients who have experienced side effects, specifically gastric ulcers from using NSAIDs for pain relief.

The study revealed that patients treated with rofecoxib or celecoxib were at lower risk for gastric ulcers during the first year of treatment than patients treated with traditional drugs. They reduced the risk of ulcer complications requiring hospital care from 1.5 percent to less than 1 percent of patients. However, the total number of side effects was comparable, although patients treated with rofecoxib (25 mg/day) were more likely to experience hypertension than those treated with traditional drugs.

"While direct-to-consumer advertising implies that some new drugs are better than existing therapies, this study shows COX-2 inhibitors are about the same at treating the symptoms of osteoarthritis or rheumatoid arthritis," said Michael O. Fleming, M.D., RxIntelligence board chairman. "They do substantially lower the risk of ulcers in arthritis patients. But for people who are not at risk of ulcers, the older, less costly drugs provide the same pain relief at lower cost."

In an economic evaluation, treatment costs for selective COX-2 inhibitors were found to be substantially higher than for the traditional NSAIDs, but may still be appropriate for patients with two or more risk factors for gastric ulcers such as age, history of GI ulcers, or use of cortisone. The economic analysis showed that in these specific cases it is more cost-effective to use selective COX-2 inhibitors alone than to use a combination of non-selective NSAIDs with other drugs protecting for ulcers (misoprostol or proton pump inhibitors).



Post a Comment

Featured Products From the ProHealth Store
Ultra ATP+, Double Strength Energy NADH™ 12.5mg FibroSleep™


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol
Mitochondria-Booster NIAGEN® Shows Promise in First Human Clinical Trial Mitochondria-Booster NIAGEN® Shows Promise in First Human Clinical Trial
Optimize Your Immune System Naturally: Thymic Protein A Optimize Your Immune System Naturally: Thymic Protein A
Block food Cravings At Their Molecular Root Block food Cravings At Their Molecular Root
Natural Bladder Control, Go Less and Live More Natural Bladder Control, Go Less and Live More

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map