ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

15 Health Benefits of Chia Seeds, According to Science

Tangerine Oil: A Citrusy Essential Oil With Well-Rounded Uses

Magnesium Deficiency Raises Your Risk of Many Chronic Ailments

Resveratrol supplementation improves arterial stiffness in type 2 diabetics

CoQ10's Potential Capabilities for Your Health

How Can Melatonin Benefit You?

Testosterone replacement therapy associated with improved urinary, sexual function

Cloves: Boost Your Immune System the Sweet and Spicy Way

8 Chia Seed Recipes

The Many Potential Health Benefits of Curcumin

 
Print Page
Email Article

Enzyme is Key in Sustained Muscle Activity, Say Scientists

  [ 31 votes ]   [ Discuss This Article ]
www.ProHealth.com • September 25, 2002


Researchers supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases have discovered that an enzyme called calcium/calmodulin-dependent protein kinase (CaMK) is a major player in activating "slow-twitch" muscles-those involved in sustained exercise like swimming or running.

A University of Texas Southwestern Medical Center team directed by R. Sanders Williams, M.D.*, developed a mouse model that produced high amounts of this enzyme in its skeletal muscle. The animals' muscles showed increased numbers of mitochondria, the energy-producing micromachines in cells, mimicking the mitochondrial increase associated with endurance exercise. The mice were also more resistant to fatigue after repeated muscle contractions, and their muscles showed increased activity of mitochondrial enzymes important in fatty acid metabolism and electron transport. In addition, CaMK was found to activate the gene PGC-1, the "master regulator" of mitochondrial proliferation in mouse muscle cells.

Some have speculated that the discovery of these effects could eventually form the science base for developing an "exercise pill." Such a pill, they say, would influence muscle-signaling pathways to confer muscle activity benefits on people whose health conditions prohibit exercising, including those with heart and respiratory conditions.

Wu H, Kanatous S, Thurmond F, Gallardo T, Isotani E, Bassel-Duby R, Williams R. Regulation of mitochondrial biogenesis in skeletal muscle by CaMK. Science 2002; 296:349-352.

*Dr. Williams is now Dean of the School of Medicine and Vice Chancellor for Academic Affairs at Duke University



Post a Comment

Featured Products From the ProHealth Store
Optimized Curcumin Longvida® Energy NADH™ 12.5mg Vitamin D3 Extreme™


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

Fatigue & Fibro Fog: Could You Have a B-12 Deficiency? Fatigue & Fibro Fog: Could You Have a B-12 Deficiency?
A Hard-Working Molecule that May Help Ease Pain & Brighten Mood A Hard-Working Molecule that May Help Ease Pain & Brighten Mood
SAD? Coping with Seasonal Affective Disorder SAD? Coping with Seasonal Affective Disorder
The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health
More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map