ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Can Autoimmune Conditions be Reversed? Researchers Make a Surprising Discovery

How One Tiny Molecule Turned into One Huge Health Breakthrough

Nutrients Boost Stem Cell Function

Humans have three times more brown body fat

B12 Proven Essential for Every Cell

Soy isoflavones may benefit breast cancer patients

How B Vitamins Improve Brain Health, Cognition, Psychiatric Problems and Mood Disorders

Dietary prebiotics improve sleep, buffer impacts of stress, says study

Ylang Ylang Oil Not Only Soothes Your Skin, but Your Mind as Well

Exercises to Help Prevent Urinary Incontinence

 
Print Page
Email Article

Enzyme is Key in Sustained Muscle Activity, Say Scientists

  [ 31 votes ]   [ Discuss This Article ]
www.ProHealth.com • September 25, 2002


Researchers supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases have discovered that an enzyme called calcium/calmodulin-dependent protein kinase (CaMK) is a major player in activating "slow-twitch" muscles-those involved in sustained exercise like swimming or running.

A University of Texas Southwestern Medical Center team directed by R. Sanders Williams, M.D.*, developed a mouse model that produced high amounts of this enzyme in its skeletal muscle. The animals' muscles showed increased numbers of mitochondria, the energy-producing micromachines in cells, mimicking the mitochondrial increase associated with endurance exercise. The mice were also more resistant to fatigue after repeated muscle contractions, and their muscles showed increased activity of mitochondrial enzymes important in fatty acid metabolism and electron transport. In addition, CaMK was found to activate the gene PGC-1, the "master regulator" of mitochondrial proliferation in mouse muscle cells.

Some have speculated that the discovery of these effects could eventually form the science base for developing an "exercise pill." Such a pill, they say, would influence muscle-signaling pathways to confer muscle activity benefits on people whose health conditions prohibit exercising, including those with heart and respiratory conditions.

Wu H, Kanatous S, Thurmond F, Gallardo T, Isotani E, Bassel-Duby R, Williams R. Regulation of mitochondrial biogenesis in skeletal muscle by CaMK. Science 2002; 296:349-352.

*Dr. Williams is now Dean of the School of Medicine and Vice Chancellor for Academic Affairs at Duke University



Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg Vitamin D3 Extreme™ Ultra ATP+, Double Strength

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

Astaxanthin - A Little-Known but Power-Packed Nutrient Astaxanthin - A Little-Known but Power-Packed Nutrient
Breakthrough Form of Magnesium Enhances Memory and Cognitive Function Breakthrough Form of Magnesium Enhances Memory and Cognitive Function
A Hard-Working Molecule that May Help Ease Pain & Brighten Mood A Hard-Working Molecule that May Help Ease Pain & Brighten Mood
Sunshine Vitamin Has D-lightful Health Benefits Sunshine Vitamin Has D-lightful Health Benefits
How One Tiny Molecule Turned into One Huge Health Breakthrough How One Tiny Molecule Turned into One Huge Health Breakthrough

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map