ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Friendly User's Guide for the Timing of Nutritional Supplements

The Health Benefits of Manuka Honey

Increase Your Magnesium Intake

Vitamin D supplementation could ease IBS symptoms

Top Tips to Boost Your Immunity

11 Amazing Health Benefits of Using Baking Soda

Nicotinamide riboside shows promise for treatment of Alzheimer’s disease

Exercise, calcium, vitamin D, and other factors linked with fewer injurious falls

Vitamin D3 Is a Powerhouse for Your Heart

Curcumin Supplementation May Impart Long-Term Cognitive Benefits

 
Print Page
Email Article

The Folic Acid-Homocysteine Connection

  [ 56 votes ]   [ Discuss This Article ]
By Source: University of Michigan Press Release, Ann • www.ProHealth.com • March 31, 1999


Years ago it was determined that increased intake of folic acid significantly reduced the risk of birth defects like spina bifida by reducing homocysteine levels. The problem was, we had yet to understand how folic acid reduced these levels. A new study that pinpoints this process may lead to a reduction in not only birth defects, but in heart attacks and strokes as well.

Researchers from the University of Michigan have unraveled the mystery behind folic acid's effectiveness by studying an enzyme called methylenetetrahydrofolate reductase, thankfully given the acronym MTHFR.

MTHFR converts homocysteine in the body to an essential amino acid called methionine. Within the MTHFR molecule is a vitamin derived molecule called flavin adenine dinucleotide or FAD. When a fairly-common genetic mutation occurs in MTHFR, it encourages the loss of FAD from the enzyme. When the levels of FAD decrease, MTHFR cannot do its job and homocysteine cannot be converted to methionine. This leaves the homocysteine to build up in blood plasma.

This is where folic acid comes in.

"Increased levels of folates help bind FAD more tightly to MTHFR—protecting the enzyme against heat inactivation and allowing the homocysteine-to-methionine conversion pathway to proceed normally," said Martha L. Ludwig, Ph.D., one of the researchers. She went on to say that folic acid supplementation would reduce homocysteine levels for humans with normal and mutated MTHFR. MTHFR mutation is present in approximately 10 percent of the population.

As mentioned, homocysteine levels have been linked to not only birth defects, but also to heart attacks and strokes. More research is necessary to determine whether or not folic acid can aid in the treatment and prevention of heart attack and stroke, but a better understanding of controlling the homocysteine associated with these diseases may be a good start.



Post a Comment

Featured Products From the ProHealth Store
Optimized Curcumin Longvida® Ultra EPA  - Fish Oil Vitamin D3 Extreme™


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get Energized with Malic Acid & Magnesium
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS
Relief for Dry, Itchy Skin Caused by Fibromyalgia Relief for Dry, Itchy Skin Caused by Fibromyalgia
Coenzyme Q10 - The Energy Maker Coenzyme Q10 - The Energy Maker
Red Yeast Rice - Natural Option for Supporting Healthy Cholesterol Red Yeast Rice - Natural Option for Supporting Healthy Cholesterol
Running on Empty? Fuel Up with NADH Running on Empty? Fuel Up with NADH

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2018 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map