ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

B Vitamins May Protect Against Damaging Effects of Air Pollution, and Improve Cognition and Psychiat...

Relief for IBS, Colitis, Crohn’s And More

Can Magnesium Relieve Your Tinnitus?

Restless Leg Syndrome (RLS) - are you running a marathon each night?

Resveratrol Proven to Slow Brain Aging

Magnesium Protects Against Stroke, Heart Disease and Diabetes

Fruits and vegetables' latest superpower? Lowering blood pressure

Neroli Oil: The Pleasantly Fragrant Citrus Oil

Restoring NAD+ could reduce DNA damage accumulation

Whole-body vibration may be as effective as regular exercise

 
Print Page
Email Article

Parvovirus Infection and Chronic Fatigue Syndrome

  [ 1160 votes ]   [ Discuss This Article ]
www.ProHealth.com • May 23, 2003


A wide variety of viral infections - enteroviruses, herpesviruses, hepatitis infections - have been implicated in precipitating Chronic Fatigue Syndrome (CFS)/ME. Among the less common causes is parvovirus B19 - an infection which is of growing interest to researchers as it can produce complications which include anaemia (the virus can replicate in the bone marrow), nerve damage (peripheral neuropathy and encephalitis), and miscarriage.

Although parvovirus infection tends to affect small children (causing 'slapped cheek syndrome') it can also cause a febrile illness with a rash and widespread joint pains (especially in the small joints of the hands, knees, and ankles) in adults. And it's something (along with certain other infections and lupus/SLE) which should always be considered in the differential diagnostic assessment of an adult with ME/CFS who starts their illness with this type of infective picture followed by persisting joint pains in addition to fatigue. Blood tests, which detect virus-specific IgG and IgM antibodies, can help to confirm the diagnosis of parvovirus B19.

Of equal importance is the fact that parvovirus B19-associated ME/CFS appears to respond to treatment. Using a form of immunological treatment known as intravenous immunoglobulin, doctors at London's Brompton Hospital have recently reported on the cases of three ME/CFS patients with parvovirus B19 infection who improved significantly after this form of treatment (400 mg/kg/day).

There have also been several clinical trials reported involving the use of iv immunoglobulin in people with ME/CFS where no specific precipitating viral infection has been identified. However, the results have been conflicting and the role of iv immunoglobulin in treating non-parvovirus B19 ME/CFS remains the subject of debate.

The doctors who treated the parvovirus B19 patients speculate that the treatment may work by helping to stabilize cytokine (immune system
chemicals) dysregulation which occurs in response to acute and ongoing infections. The recovered patients also had evidence of a considerably reduced viral load (i.e., clearance of their viraemia) after treatment.

Overall, these are interesting results which suggest that further assessment of immunoglobulin therapy in other sub-groups, where there is a clear post-infectious onset to ME/CFS, is warranted. This small but important study also emphasizes why I believe the MRC have got it so wrong when they conclude that research into causal factors (including the role of infection and the immunological response to infection) should not be given any high priority.

Source: Clinical Infectious Diseases, 2003,36,E100-106

NB: Other infections which can precipitate an arthralgia/joint pain and fatigue syndrome include brucellosis, leptospirosis, Lyme disease, and yersinia - some of which can be treated with drugs (ref: 'Living with ME', p41: 'The post-infectious arthralgia and myalgia fatigue syndrome').


Dr. Charles Shepherd



Post a Comment

Featured Products From the ProHealth Store
Ultra ATP+, Double Strength Vitamin D3 Extreme™ Mitochondria Ignite™ with NT Factor®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Can Autoimmune Conditions be Reversed? Researchers Make a Surprising Discovery Can Autoimmune Conditions be Reversed? Researchers Make a Surprising Discovery
Probiotic Mint Promotes Healthy Gums & Teeth, Freshens Breath and Whitens Teeth Probiotic Mint Promotes Healthy Gums & Teeth, Freshens Breath and Whitens Teeth
Could a B-12 Deficiency Be Causing Your Symptoms? Could a B-12 Deficiency Be Causing Your Symptoms?
D-ficient? Health Risks You Need to Know About D-ficient? Health Risks You Need to Know About
SAD? Coping with Seasonal Affective Disorder SAD? Coping with Seasonal Affective Disorder

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map