ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Scientifically-designed fasting diet lowers risks for major diseases

More evidence for calorie restriction’s longevity effect

Supplementation with vitamin D associated with improved testosterone, erectile function among middle...

A Little Zinc Goes a Long Way

Vitamin D deficiency increases risk of chronic headache

VIDEO: The Best Brain Foods That Help Increase Your Memory!

Get the Most From Your Green Tea

Iron (And More) For Lasting, Natural Energy

Metabolic syndrome increases the need for vitamin E

Supplement combo improves bone density, mood, in postmenopausal women

 
Print Page
Email Article

Study Shows Long-Term Stress Appears to Damage Caregivers' Immune Systems

  [ 99 votes ]   [ Discuss This Article ]
www.ProHealth.com • June 30, 2003


CHAPEL HILL -- Taking care of chronically ill loved ones over long periods stresses caregivers, as everyone knows, but a new study provides strong new evidence that such continuing stress boosts the risk of age-related diseases by prematurely aging caregivers' immune systems.

Levels of a damaging compound known as a proinflammatory cytokine not only increased considerably faster among those taking care of ailing spouses but also continued to increase faster for years after the spouses died.

A report on the research, conducted by scientists at Ohio State University and the University of North Carolina at Chapel Hill, will appear online Monday afternoon (June 30) in the Proceedings of the National Academy of Sciences.

Authors are Drs. Janice K. Kiecolt-Glaser, Cathie Atkinson, William B. Malarkey and Ronald Glaser of Ohio State's College of Medicine and Drs. Robert C. MacCallum and Kristopher J. Preacher of UNC's department of psychology, College of Arts and Sciences.

"Our study examined effects of a long-term chronic stress situation on overproduction of the cytokine IL-6 in older adults," said MacCallum, director of the L.L. Thurstone Psychometric Laboratory at UNC. "IL-6 is a substance secreted by a variety of cells in the body, including blood cells and bone marrow. Among other things, it is associated with the functioning of the immune system in its response to challenges, as well as the inflammatory response to injury and infection."

As people age, production of IL-6 tends to increase, he said. Overproduction of IL-6 has been linked to a variety of age-related conditions, including cardiovascular disease, arthritis, periodontal disease, frailty and diabetes.

The study involved examining IL-6 levels in two groups of older adults over six years. One group of 119 people consisted of men and women who were caring for a spouse with dementia, usually Alzheimer's disease. The other group consisted of 106 people who were not caregivers. When they entered the investigation, subjects' average age was 70.5 years.

"Statistical analyses showed a more rapid increase in IL-6 level for the caregiver group than for the non-caregiver group, such that the average rate of increase was about four times greater in the caregiver group," MacCallum said.

The team carried out additional analyses to learn whether the difference might be associated with other variables such as age, gender, ethnicity, depression, loneliness or health-related behaviors including smoking, exercise and sleep patterns.

"We found no other variables that accounted for the group difference in rate of change in IL-6," MacCallum said.

Before and during the study, some of the spouses of the caregivers died, he said. Further analyses compared levels of the proinflammatory cytokine in former caregivers and those who continued taking care of their loved ones. Results showed no significant difference in rate of change in IL-6 between the two groups, indicating that the negative impact of caregiving may last long after the ill spouse has died.

"Overall, the study provides evidence that a severe chronic stress situation can accelerate production of IL-6, a phenomenon which has been shown to be associated with the onset and course of a variety of age-related diseases and conditions," MacCallum said. "In effect



Post a Comment

Featured Products From the ProHealth Store
Mitochondria Ignite™ with NT Factor® Energy NADH™ 12.5mg FibroSleep™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

Aching Muscles? Top 10 Nutrients to Take Back Your Life Aching Muscles? Top 10 Nutrients to Take Back Your Life
Breaking Through the Mental Fog Breaking Through the Mental Fog
Clinically Studied Joint Relief Product for FM & ME/CFS Clinically Studied Joint Relief Product for FM & ME/CFS
Guarding Against the Dangers of Vitamin D Deficiency Guarding Against the Dangers of Vitamin D Deficiency
When a Negative is Positive - Goodnighties Recovery Sleepwear When a Negative is Positive - Goodnighties Recovery Sleepwear

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map