ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

B Vitamins May Protect Against Damaging Effects of Air Pollution, and Improve Cognition and Psychiat...

Relief for IBS, Colitis, Crohn’s And More

Can Magnesium Relieve Your Tinnitus?

Resveratrol Proven to Slow Brain Aging

Magnesium Protects Against Stroke, Heart Disease and Diabetes

Fruits and vegetables' latest superpower? Lowering blood pressure

Neroli Oil: The Pleasantly Fragrant Citrus Oil

Restoring NAD+ could reduce DNA damage accumulation

What Benefits Can You Derive From Patchouli Oil?

Astaxanthin Is a Longevity Promoter

 
Print Page
Email Article

Researchers Believe Chemical in Green Tea Reduces Cancer Risk

  [ 162 votes ]   [ Discuss This Article ]
www.ProHealth.com • August 6, 2003


Green tea's health benefits are even more potent and varied than scientists suspected, say researchers who have discovered that chemicals in green tea appear to shut down one of the key molecules that tobacco relies upon to cause cancer. It's a find that could help explain why research has shown that people who drink green tea are less likely to develop cancer. The finding by scientists at the University of Rochester's Environmental Health Science Center appears in the July 21 issue of Chemical Research in Toxicology, published by the American Chemical Society.

Graduate student Christine Palermo and adviser Thomas Gasiewicz, Ph.D., set out to measure the effects of the chemicals found in green tea on a molecule known as the aryl hydrocarbon (AH) receptor, a molecule that frequently plays a role in turning on genes that are oftentimes harmful. Gasiewicz has previously shown how both tobacco smoke and dioxin manipulate the molecule – a favorite target of toxic substances – to cause havoc within the body.

The team isolated the chemicals that make up green tea and found two that inhibit AH activity. The two substances, epigallocatechingallate (EGCG) and epigallocatechin (EGC), are close molecular cousins to other flavonoids found in broccoli, cabbage, grapes and red wine that are known to help prevent cancer.

Scientists know that green tea contains chemicals that are anti-oxidants and quench harmful molecules, but just how the substance works has been a mystery. Its effects on the AH receptor have not been thoroughly evaluated until now.

"It's likely that the compounds in green tea act through many different pathways," says Gasiewicz, professor and chair of Environmental Medicine and director of Rochester's Environmental Health Science Center. "Green tea may work differently than we thought to exert its anti-cancer activity."

Gasiewicz and Palermo showed that the chemicals shut down the AH receptor in cancerous mouse cells, and early results indicate the same is true in human cells as well.

In the laboratory the AH-inhibiting effects of green tea become evident when EGCG and EGC reach levels typical of those found in a cup of green tea. But the scientists say that how green tea is metabolized by the body is crucial to its effectiveness, and that results in the laboratory don't necessarily translate directly to the dinner table.

"Right now we don't know if drinking the amount of green tea that a person normally drinks would make a difference, but the work is giving us insight into how the proteins work," says Palermo, who enjoys cold green tea herself. "There are a lot of differences between various kinds of green tea, so a lot more research is needed."

For this work Palermo received the award for best poster in the chemical carcinogenesis specialty section at the meeting of the Society of Toxicology in March. Now she is studying exactly how green tea inhibits the AH receptor. After she graduates Palermo plans to study links between environmental agents and childhood leukemia.

In addition to Palermo and Gasiewicz, other authors are former post-doctoral associate Jose Martin Hernando and chemist Andrew Kende, who teased apart the components of green tea extract; and Stephen Dertinger, a former student who first had the idea to test green tea's effects on the AH receptor. The work was funded by the National Institute of Environmental Health Sciences and the American Institute for Cancer Research.

SOURCE: University of Rochester Medical Center http://www.urmc.rochester.edu/pr/News/news.cfm?ID=342.



Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg FibroSleep™ Mitochondria Ignite™ with NT Factor®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Prepare Yourself for Cold & Flu Season Prepare Yourself for Cold & Flu Season
Soothe, Heal and Regulate Your Digestive System with Nutrient-Rich Aloe Vera Soothe, Heal and Regulate Your Digestive System with Nutrient-Rich Aloe Vera
Coping When Colds or Flu Catch Up with You Coping When Colds or Flu Catch Up with You
Coconut Oil - Healthy Gifts from the 'Tree of Life' Coconut Oil - Healthy Gifts from the 'Tree of Life'
Looking for Energy? Turn to Plants. Looking for Energy? Turn to Plants.

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map