by Garth L Nicolson, PhD, Rita Ellithorpe, MD, Robert Settineri, MS
May 28, 2009
[Note: the full text of this article with charts is available free online in the Spring 2009 issue of the Journal of IiME - http://bit.ly/3PvOQ. Dr. Nicolson presented the results at the recent International IiME Conference.]
Often Chronic Fatigue Syndrome (CFS) patients have weight issues, and weight reduction regimens can increase fatigue.
Therefore, we initiated a weight loss clinical trial using an all natural oral supplement mixture containing an FDA-approved amylase inhibitor plus NTFactor®, which is known to safely reduce fatigue in aged subjects, chronic fatigue, and CFS.
The objective was to see if subjects could safely lose weight without increasing appetite and fatigue and without changing eating or exercise patterns or using drugs, herbs or caffeine.
A 2-month open label clinical trial was initiated with 30 patients who used an oral mixture (Healthy Curb™) of amylase inhibitor (500 mg white kidney bean extract) plus 500 mg of NTFactor 30 min before each meal.
Weight and measurements were taken weekly, appetite was assessed and fatigue was determined using the Piper Fatigue Scale.
• Sixty-three percent of the participants lost an average of 3 pounds, with average reductions of 1.5 and 1 inch waist and hip circumference, respectively.
• Participants experienced gradual and consistent weight loss along with waist and hip, body mass index (BMI) and basal metabolic rate (BMR) reductions during the entire trial.
• There was a 44% reduction in overall hunger with reduced cravings for sweets; therefore, notable appetite suppression occurred.
• Using the Piper Fatigue Scale the entire test group showed an average of 23% decrease in overall fatigue.
• Blood lipid profiles generally improved, suggesting improved cardiovascular health,
• And no adverse effects were noted clinically or found in blood chemistries.
Conclusions: The vast majority of the subjects in this trial lost weight, showed decreased waist and hip measurements and overall body mass. Their overall fatigue was reduced, and they experienced marked appetite suppression. The product was completely safe and void of any side effects and was extremely well tolerated. Healthy Curb appears to be a safe and effective means for CFS patients to manage weight without changes in eating or exercise patterns.
Source: Journal of IiME (Invest in ME), Spring 2009, 3(1), pp 39-48. Nicolson GL, Ellithorpe R, Settineri R. The Institute for Molecular Medicine, Huntington Beach (www.immed.org); Tustin Longevity Center Tustin; Sierra Productions, Irvine, California, USA. [E-mail: gnicolson@immed.org]
|
