ProHealth lyme Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Five Supplements That Support The Immune System

Be Your Own Researcher: Treat Chronic Pain as a Daily Experiment

Five Things You Should Never Say to a Person with Chronic Illness...And What To Say Instead

You Can Use Mindfulness to Choose How to Live

My current treatment protocol for chronic Lyme and fibromyalgia

“WWJD?”

Lyme Disease Causes Obsessive-Compulsive Symptoms

Lyme disease may cause facial palsy and myocarditis that mimics myocardial infarction

Tai Chi and Qigong May Improve Motor Function, Depression and Other Symptoms in Lyme-Related Parkins...

Imaging Reveals Stem Cell Therapy to Support Brain Recovery in Lyme Patients

 
Print Page
Email Article

Host Immune Evasion by Lyme and Relapsing Fever Borreliae: Findings to Lead Future Studies for Borrelia miyamotoi

  [ 3 votes ]   [ Discuss This Article ]
By By BL Stone and CA Brissette • www.ProHealth.com • February 16, 2017


To read the entire article for free, click here.
 
Abstract
 
The emerging pathogen, Borrelia miyamotoi, is a relapsing fever spirochete vectored by the same species of Ixodes ticks that carry the causative agents of Lyme disease in the US, Europe, and Asia. Symptoms caused by infection with B. miyamotoi are similar to a relapsing fever infection.
 
However, B. miyamotoi has adapted to different vectors and reservoirs, which could result in unique physiology, including immune evasion mechanisms. Lyme Borrelia utilize a combination of Ixodes-produced inhibitors and native proteins [i.e., factor H-binding proteins (FHBPs)/complement regulator-acquiring surface proteins, p43, BBK32, BGA66, BGA71, CD59-like protein] to inhibit complement, while some relapsing fever spirochetes use C4b-binding protein and likely Ornithodoros-produced inhibitors.
 
To evade the humoral response, Borrelia utilize antigenic variation of either outer surface proteins (Osps) and the Vmp-like sequences (Vls) system (Lyme borreliae) or variable membrane proteins (Vmps, relapsing fever borreliae). B. miyamotoi possesses putative FHBPs and antigenic variation of Vmps has been demonstrated.
 
This review summarizes and compares the common mechanisms utilized by Lyme and relapsing fever spirochetes, as well as the current state of understanding immune evasion by B. miyamotoi.
 
Source: By Stone BL and Brissette CA. Host Immune Evasion by Lyme and Relapsing Fever Borreliae: Findings to Lead Future Studies for Borrelia miyamotoi.
Front Immunol. 2017 Jan 19;8:12. doi: 10.3389/fimmu.2017.00012. eCollection 2017.




Post a Comment

Featured Products From the ProHealth Store
Pro-C Complex™ Ubiquinol CoQ-10 Vitamin E with Mixed Tocopherols


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Pro-C Complex™ Pro-C Complex™
Buffered Vitamin C for Enhanced Absorption
Vitamin D3 5000 IU Vitamin D3 5000 IU
Give Your Body a Boost With the Sunshine Vitamin
Omega 3-6-9 Omega 3-6-9
All three EFAs in one convenient form
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Acidophilus Pearls Acidophilus Pearls
Guaranteed active cultures for better digestion

Natural Remedies

Probiotic Mint Promotes Healthy Gums & Teeth, Freshens Breath and Whitens Teeth Probiotic Mint Promotes Healthy Gums & Teeth, Freshens Breath and Whitens Teeth
Herbal Rescue for High Blood Sugar Herbal Rescue for High Blood Sugar
Three-Step Strategy to Reverse Mitochondrial Aging Three-Step Strategy to Reverse Mitochondrial Aging
The Brain Boosting and Fatigue Fighting B-12 The Brain Boosting and Fatigue Fighting B-12
More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2018 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map