ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|

Trending News

How I Recovered From ME/CFS

The Functional Capacity Evaluation (FCE) and Your Disability Insurance Benefits

HIV, Heart Disease, Diabetes … and Chronic Fatigue Syndrome? The Unutmaz Project to Decode ME/CFS

Stanford Study Finds Brain Abnormalities in ME/CFS Patients

New Option For Chronic Fatigue Syndrome

A Chronic Fatigue Syndrome Brain on Exercise – Not a Pretty Sight

Ask the Doctor: Why is the MTHFR gene important?

What You Need to Know About Folate and B12

What is in a name? Comparing diagnostic criteria for chronic fatigue syndrome with or without fibrom...

SURVEY RESULTS: Cognitive Impairment

 
Print Page
Email Article

Fibromyalgia pain associated with premature chromosomal telomere shortening: University of Michigan

  [ 25 votes ]   [ 1 Comment ]
www.ProHealth.com • October 11, 2012


Article:
Pain is associated with short leukocyte telomere length in women with fibromyalgia
– Source: Journal of Pain, Oct 2012

By Afton L Hassett, et al.

[ Ed Note: A full text, illustrated pdf poster of this important new research (abstract below), is available at http://cdn.f1000.com/posters/docs/250162731. Emerging research also strongly suggests oxidative stress / inflammation plays a role in telomere shortening, and that essential nutrients may play a crucial role in telomere health. See for example:

“Omega-3 Trial Suggests ‘Nutritional Supplement Might Actually Make a Difference in Aging'” (trial at Ohio State reported telomere preservation in omega-3 supplemented cohort vs controls)

"Nutrition for Healthy Telemeres – May Help Slow the Biological Clock" (a review of research on telomere destruction and benefits of nutritional support) ]

Abstract:
Telomere length, considered a measure of biological aging, is linked to morbidity and mortality.

Psychosocial factors associated with shortened telomeres are also common in chronic pain; yet, little is known about telomere length in pain populations.

Leukocyte telomere length was evaluated in 66 women with fibromyalgia and 22 healthy female controls.

Participants completed questionnaires and a subgroup of fibromyalgia patients underwent quantitative sensory testing (QST; n = 12) and neuroimaging (n = 12).

Telomere length was measured using the quantitative polymerase chain reaction method.

• Although patients had shorter telomere length than controls, the difference was not statistically significant.

• However, higher levels of pain within fibromyalgia were associated with shorter telomere length (P = .039).

• When pain and depression were combined, patients categorized as high-pain/high-depression had an age-adjusted telomere length 265 base pairs shorter than those with low-pain/low-depression (P = .043), a difference consistent with approximately 6 years of chronological aging.

In the subset tested, telomere length:

• Was also related to pain threshold and pain sensitivity as well as gray matter volume,

• Such that patients with shorter telomeres were more sensitive to evoked pain and had less gray matter in brain regions associated with pain processing (e.g., primary somatosensory cortex).

These preliminary data support a relationship between pain and telomere length.

PERSPECTIVE:

Our findings support a link between premature cellular aging and chronic pain. These preliminary data imply that chronic pain is a more serious condition than has typically been recognized in terms of bodily aging.

Source: Journal of Pain, Oct 2012; 13(10):959-69. PMID:23031395, by Hassett AL, Epel E, Clauw DJ, Harris RE, Harte SE, Kairys A, Buyske S, Williams DA. Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan. E-mail: afton@med.umich.edu]



Please Discuss This Article:   Post a Comment 

Omega 3's
Posted by: shafm
Oct 21, 2012
Omega 3's take different forms to assist with telomere shortening - sardine oil in veggie cpsules, flax seed oil caps + seeds, ground ,krill oil from seafood ( watch for allergen), Chia Seeeds -highest plant derivitve of naturla Omega 3, then there is Omega 3, 5, 9, combo, for people who are fish/+ vegetarians this is esp nb, as Omega 6 + ( is obtained mainly from poultry- use free range grain fed, no BST anti biotics if you do eat poultry esp FM sufferers. Omega 3's are essential to brain systems, and body organs to function @ optimal levels, assist prematur cts, as well as dopamine levels and many other essential funtions of brain and body. Sharon Levin head FM Southern Africa Support + Education. www.fibromyalgiasa.co.za
Reply Reply
 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Immune Support Supplements

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness

Natural Remedies

Sunshine Vitamin Has D-lightful Health Benefits Sunshine Vitamin Has D-lightful Health Benefits
The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health
Green Coffee Extract: Unique Obesity Intervention Green Coffee Extract: Unique Obesity Intervention
Rejuvenating the Brain - How PQQ Helps Power Up Mental Processing Rejuvenating the Brain - How PQQ Helps Power Up Mental Processing
Live Longer: Groundbreaking Research on Omega-3s Live Longer: Groundbreaking Research on Omega-3s

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing