Activate Now
 
ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Ten Tips to Simplify, Lower the Cost, and Optimize CFS and fibromyalgia Treatment

Ampligen Takes Big Step Forward - Becomes First Drug Approved Anywhere For Chronic Fatigue Syndrome

Patient Insights into the Design of Technology to Support a Strengths-Based Approach to Health Care.

Lipkin's Monster ME/CFS Study: Microbes, Immunity & Big Data

Keep Learning – Even From Bed!

Iron Man: A Young Person's POTS ME/CFS Recovery Story Pt. I

Buying Drugs from Canada - A Good Choice for Fibromyalgia and Chronic Fatigue Syndrome (ME/CFS)?

VIDEO: Dear Healthy People: Fatigue

Researchers Identify Characteristic Chemical Signature for Chronic Fatigue Syndrome

SURVEY: Weight Management & Chronic Illness

 
Print Page
Email Article

Strong Evidence of a Genetic Link in Fibromyalgia

  [ 63 votes ]   [ 2 Comments ]
www.ProHealth.com • January 4, 2013


Strong Evidence of a Genetic Link in FibromyalgiaArticle:

The fibromyalgia family study: A genome-scan linkage study.

– Source:  Arthritis and Rheumatism, December 28, 2012. [Epub ahead of print]

By Lesley M. Arnold, et al.



Abstract:

Objective:  Familial aggregation of fibromyalgia has been increasingly recognized. The goal of the current study was to conduct a genome wide linkage scan to identify susceptibility loci for fibromyalgia.

Methods:  We genotyped members of 116 families from the Fibromyalgia Family Study and performed a model-free genome-wide linkage analysis of fibromyalgia with 341 microsatellite markers, using the Haseman-Elston regression approach.

Results:  The estimated sibling recurrence risk ratio (?(s) ) for fibromyalgia was 13.6 (95% CI: 10.0-18.5), based on a reported population prevalence of 2%. Genome-wide suggestive evidence of linkage was found at marker D17S2196 (Empirical P =0.00030) and D17S1294 (Empirical P =0.00035) on chromosome 17p11.2-q11.2.

Conclusion:  The estimated sibling recurrence risk ratio suggests a strong genetic component of fibromyalgia.

This is the first study to report genome-wide suggestive linkage of fibromyalgia to the chromosome 17p11.2-q11.2 region.

Further investigation of these multi-case families from the Fibromyalgia Family Study is warranted to identify potential causal risk variants for fibromyalgia. © 2012 American College of Rheumatology.

Source:  Arthritis and Rheumatism, December 28, 2012. [Epub ahead of print]. By Lesley M. Arnold, I. Jon Russell, Muhammad B. Yunus, M.A. Khan, I. Kushner, J.M. Olson, S.K. Iyengar. Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio. E-mail: Lesley.Arnold@uc.edu.





Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg Hydroxocobalamin Extreme™ B-12 Extreme™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments Post a Comment

nice to know
Posted by: roge
Jan 4, 2013
genetic link was highly suspected for years and good to get more confirmation but researchers what are you doing to help better treat this horrible disease and gain a better understanding of the pathology . I can assure everyone with FM would rather have that answered then if this runs in families - can we please get come priority setting here with regards to how research dollars are spent here - man o man.
Reply Reply

"Genetic link?" I hope to shout!
Posted by: tursiops
Jan 16, 2013
I got sick in June 1981, at age 42. My daughter got sick several years later, at age 34. Within a year, she was no longer
able to work.
Recently, she has in addition, been diagnosed with MS.

My son, a few years later, came down with it too, he was 42.

And can anybody help me get the full spectrum of tests for hypo-
thyrodism? My doctor absolutely REFUSES to do anything but the
THS test,citing it as the most 'sensitive.' Everything I've read
about it shows that, if you don't know the results of the T3, T4
tests, you aren't getting the full picture. And, given that I am
a tall, plus size lady, does the dosage for thyroid replacement
for a 5' tall, 98 pound person seem adequate for someone larger?
I have taken him articles written by doctors, for doctors, and
he won't even read them. Why do I keep him as my PCP? I live in
a rural area. Only choice.
Reply Reply
 
Natural Pain Relief Supplements

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 Your Brain Needs for Detox & Sharpness
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Breaking Through the Mental Fog Breaking Through the Mental Fog
Safely Burn Away Body Fat Safely Burn Away Body Fat
Guarding Against the Dangers of Vitamin D Deficiency Guarding Against the Dangers of Vitamin D Deficiency
Energy Breakthrough - One Fibromyalgia Patient’s Fortuitous Discovery Energy Breakthrough - One Fibromyalgia Patient’s Fortuitous Discovery
Cell-Charging Compound Gives Steady Energy to Fibromyalgia & Chronic Fatigue Patients Cell-Charging Compound Gives Steady Energy to Fibromyalgia & Chronic Fatigue Patients

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map