ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|

Trending News

The Muscle-Brain Connection in ME/CFS Revealed

The Neurobiology of ME/CFS

P2P: The Question They Will Not Ask

Interview: Jennifer Brea Talks About Obstacles, Adjustments, and Inspiration

Adrenal Burnout? Naturally Boost Your Energy & Manage Stress

Smartphone app and specialised clinic for chronic fatigue patients

DNA Methylation Modifications Associated with Chronic Fatigue Syndrome

Stress management skills, cortisol awakening response, and post-exertional malaise in Chronic Fatigu...

VIDEO: Dr. Newton Talks About Biomarkers and the Future of ME/CFS Treatment

Curcumin Made 65X More Bioavailable - Modern Take on a "Golden" Spice Busts Brain Fog, Joint & Body ...

 
Print Page
Email Article

Brain-Derived Neurotrophic Factor Correlates with Depression Intensity in Fibromyalgia Patients

  [ Not Yet Rated ]   [ Discuss This Article ]
www.ProHealth.com • February 9, 2013


[Note: Brain-derived neurotrophic factor (BDNF) is a protein that is a member of the neurotrophin family of growth factors.  It acts on certain types of nerve cells, enabling them to grow and survive.  It is primarily located in the central nervous system, where it acts on cells in the brain and the eye.]

Article:

Serum level of brain-derived neurotrophic factor in fibromyalgia syndrome correlates with depression but not anxiety.
– Source: Neurochemistry International, January 11, 2013

By B. Nugraha, C. Korallus and C. Gutenbrunner

Abstract:

Brain-derived neurotrophic factor (BDNF) has been known to play a role in fibromyalgia syndrome (FMS) patients. Depression and anxiety are quite common additional symptoms in FMS. However the role of BDNF in these symptoms still needs to be elucidated. Although BDNF has been shown to be relevant in major depression, however studies could not show such differences between FMS patients with and without major depression.

As mood-related symptom occurs frequently and differs in its intensity in FMS patients, BDNF level should be measured in subgroup regarding depression and anxiety scale. Therefore the aim of this study was to evaluate the correlation of BDNF in serum of FMS with intensity of depression and anxiety. Additionally, interleukin (IL)-6 was measured.

  • This study showed that serum level of BDNF was age-dependent in Hcs [healthy controls].

  • FMS patients had higher level of serum BDNF as compared to HC.

  • Additionally, serum level of BDNF showed correlation with depression, but not with anxiety.

  • Serum level of BDNF increased with depression score in FMS.

  • However, serum level of IL-6 was not correlated with both depression and anxiety scores.

Taken together, BDNF is involved in the pathophysiology of FMS. Additionally, it seems to be correlated with intensity of depressive symptoms in FMS.


Source: Neurochemistry International, January 11, 2013. By B. Nugraha, C. Korallus and C. Gutenbrunner. Deparment of Rehabilitation Medicine, Hannover Medical School, Hannover, Germany; Deparment of Chemistry, University of Indonesia, Depok, Indonesia. Electronic address: Nugraha.Boya@mh-hannover.de.




Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Your Next Order

Featured Products

B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness

Natural Remedies

A Breakthrough for Mitochondrial Dysfunction A Breakthrough for Mitochondrial Dysfunction
Green Coffee Extract: Unique Obesity Intervention Green Coffee Extract: Unique Obesity Intervention
Are You Obtaining the Proper Enzymes? Are You Obtaining the Proper Enzymes?
Repair Damaged Mitochondria and Reduce Fatigue Up to 45% Repair Damaged Mitochondria and Reduce Fatigue Up to 45%
The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing