ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

“Medical Game-Changer” To Shed New Light on Neuroimmune Diseases

The ME Association Illness Management Report: “No decisions about me, without me”

Phase II Cyclophosphamide trial for ME gets under way

Fatigue & Fibro Fog: Could You Have a B-12 Deficiency?

5 Tips for When Motivation Runs Out

Tipping Point? The Stanford Chronic Fatigue Initiative’s Big Year Is Here

There's This Friend I Have...

VIDEO: Dr. Light Compares Fatigue in ME/CFS to Cancer, MS, and Fibromyalgia

Powerful Anti-Herpes Drug Moves Forward: Hope for ME/CFS/FM Patients

The 4I Hypothesis: A Neuro-Immunological Explanation for Characteristic Symptoms of Myalgic Encephal...

 
Print Page
Email Article

Is Chronic Fatigue Syndrome in Older Patients a different disease? – a clinical cohort study

  [ 9 votes ]   [ 2 Comments ]
www.ProHealth.com • February 13, 2013


Is Chronic Fatigue Syndrome in Older Patients a different disease? – a clinical cohort study

  –Source: Eur J Clin Invest, 2012

Abstract

Background: Chronic fatigue syndrome (CFS) is a disabling disorder characterised by persistent fatigue with a typical age of diagnosis of 35–50 years. CFS does present in those aged over 50 but whether this is a different disease in older age groups has not been considered. Therefore, we performed a clinical cohort study to examine and differentiate the clinical and autonomic features in CFS patients aged over 50.

Design: A total of 179 Fukuda diagnosed CFS patients were recruited, and 25 older CFS patients (50 + years) were matched case by case for gender and length of history to 25 younger CFS patients (16–29 years). A range of symptomatic-based questionnaires were used in addition to heart rate variability and baroreceptor sensitivity to assess autonomic function.

Results: Chronic fatigue syndrome can present for the first time in an older population. Older CFS patients demonstrate increased fatigue (Fatigue impact scale; 85 ± 33 vs. 107 ± 27, P = 0·02) (Chalder fatigue scale; 9 ± 3 vs. 11 ± 1, P = 0·002) and caseness for depression (Hospital Anxiety and Depression scale; 7 ± 3 vs. 10 ± 4; P = 0·005). There is a greater autonomic dysfunction in older CFS patients, with reduced parasympathetic function (HFnu; 49·1 ± 18 vs. 36·2 ± 18, P = 0·01, RR30 : 15; ± , P = 0·02) and increased sympathetic function (LFnu; 51·5 ± 17 vs. 63·8 ± 18, P = 0·01). Baroreflex sensitivity was substantially reduced (BRS; 19·7 ± 12 vs. 9·9 ± 5, P = 0·0004), and left ventricular ejection time prolonged (LVET; 274·6 ± 16 vs. 285·8 ± 9, P = 0·004).

Conclusions: Older CFS patients demonstrate a disease phenotype very different from younger patients. The combination of differing underlying pathogenic mechanisms and the physiological aspects of ageing result in a greater disease impact in older CFS patients.

Source: Eur J Clin Invest, 2012. Article first published online: 9 Feb 2013 [doi: 10.1111/eci.12046]. Ieuan Lewis, Institute for Ageing & Health, Newcastle University, Newcastle upon Tyne, UK; Jessie Pairman, Newcastle Hospitals NHS Foundation Trust, Northern CFS Clinical Network, Newcastle upon Tyne, UK; Gavin Spickett, Newcastle Hospitals NHS Foundation Trust, Northern CFS Clinical Network, Newcastle upon Tyne, UK; Julia L. Newton, Institute for Ageing & Health, Newcastle University, Newcastle upon Tyne, UK, Newcastle Hospitals NHS Foundation Trust, Northern CFS Clinical Network, Newcastle upon Tyne, UK NIHR Biomedical Research Centre in Ageing, Newcastle University, Newcastle upon Tyne, UK.




Please Discuss This Article:   Post a Comment 

Is this about CFS another name for ME or about psychiatry messing around
Posted by: simmons1
Feb 14, 2013
not to long ago back in the dark ages of my ME childhood children were claimed not to get ME instead school phobia was given as a reason for why children were believing themselves sick or Munchhausen by proxy were the mother was accused of creating ME in the minds of their children by psychiatrists . Now that i am getting older my ME is going to be put down to psychological problems due to old age a totally separate ME from my younger ME version of myself can i trust this research ,is it about old age or ME or is it just another psychological fix up job another spin to make ME the non disease lumped in with some sort of old age psychological theory to damage ME.
Reply Reply

I may have got this wrong
Posted by: simmons1
Feb 15, 2013
I may have jumped to conclusion here as I may have mistaken physiological aspects of aging as psychological aspects of aging I have also discovered that Gavin Spickett works in Immunology in Newcastle and this is an area that has an important part to play in researching ME .I apologize for being Hasty and harsh in my comment here it is very hard to determine what is going on in ME and should have checked my facts it is important that science looks into this illness .
Reply Reply
 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Milk Thistle: Trusted Support for Health & Healing in a Toxic World Milk Thistle: Trusted Support for Health & Healing in a Toxic World
Olea25 Olive Hydroxytyrosol Hits Astonishing 68,000+ ORAC Antioxidant Value Olea25 Olive Hydroxytyrosol Hits Astonishing 68,000+ ORAC Antioxidant Value
Block Acid Reflux to Prevent Esophageal Problems! Block Acid Reflux to Prevent Esophageal Problems!
Probiotic Mint Promotes Healthy Gums & Teeth, Freshens Breath and Whitens Teeth Probiotic Mint Promotes Healthy Gums & Teeth, Freshens Breath and Whitens Teeth
Dreaming of a Good Night's Sleep? Dreaming of a Good Night's Sleep?

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing