ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Not Just an "Ill Person" - Ways to expand your identity when you're chronically ill

Is Poor Sleep Pummeling the Immune System in ME/CFS and Fibromyalgia? A Vicious Circle Examined

Taking a Moment

Glial Cell Inhibitors: The Next Sleep Drugs for Fibromyalgia and Chronic Fatigue Syndrome (ME/CFS)?

Staying Connected with Friends While Ill

VIDEO: Illness and Isolation

Inflammation correlates with symptoms in chronic fatigue syndrome

Call Out the Imbalance in Current Policy Making for Pain Management and Prescription Opioid Use

The Secret to Chronic Happiness as You Age

Molecular Underpinnings of ME/CFS Explored at the Open Medicine Foundation Symposium

 
Print Page
Email Article

Immunostimulation in the treatment for chronic fatigue syndrome/myalgic encephalomyelitis

  [ 6 votes ]   [ 1 Comment ]
By A. D. Proal et al. • www.ProHealth.com • April 18, 2013


By A.D. Proal  et al.

Abstract

Chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME) has long been associated with the presence of infectious agents, but no single pathogen has been reliably identified in all patients with the disease. Recent studies using metagenomic techniques have demonstrated the presence of thousands of microbes in the human body that were previously undetected and unknown to science. More importantly, such species interact together by sharing genes and genetic function within communities. It follows that searching for a singular pathogen may greatly underestimate the microbial complexity potentially driving a complex disease like CFS/ME. Intracellular microbes alter the expression of human genes in order to facilitate their survival. We have put forth a model describing how multiple species - bacterial, viral, and fungal - can cumulatively dysregulate expression by the VDR nuclear receptor in order to survive and thus drive a disease process. Based on this model, we have developed an immunostimulatory therapy that is showing promise inducing both subjective and objective improvement in patients suffering from CFS/ME.

SourceImmunol Res. 2013 Apr 11. [Epub ahead of print]. Proal AD, Albert PJ, Marshall TG, Blaney GP, Lindseth IA. Autoimmunity Research Foundation, 3423 Hill Canyon Ave, Thousand Oaks, CA, 91360, USA.





Post a Comment

Featured Products From the ProHealth Store
MitoQ® Hydroxocobalamin Extreme™ Energy NADH™ 12.5mg


Article Comments Post a Comment

summary of article
Posted by: Sandy10m
Apr 28, 2013
Here is a general summary of the article. First, these authors believe that CFS and other disease processes are caused by a combination of infections that interplay with each other and your body. This may be why CFS has such a broad range of symptom sets. However, the bottom line is that some CFS patients have VDR (Vitamin D3 receptor) dysregulation. VDR is a 1,25 dihydroxyvitamin D3-activated member of the nuclear receptor superfamily of transcription factors. The diseases manipulate the Vit D3 receptors on cells and interfere with the use of Vit D3. Your blood tests may show a low level of 25-D in your blood (the raw material to make 1,25-D) but a high level of 1,25-D (the immediately usable form). One treatment that they are using in this paper is stimulating the immune system to respond. They use Olmesartan to do this. The patients will usually feel much worse for a long time, but then they slowly start to feel better, and some are cured. If you fall into this category of CFS, you might want to talk to your doctor about this treatment.
Reply Reply
 
Optimized Curcumin Longvida with Omega-3

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 Your Brain Needs for Detox & Sharpness
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Herbal Inflammation Management for Whole Body Health Herbal Inflammation Management for Whole Body Health
Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel
Bone Broth Benefits for Digestion, Arthritis and Cellulite Bone Broth Benefits for Digestion, Arthritis and Cellulite
Green Coffee Extract: Unique Obesity Intervention Green Coffee Extract: Unique Obesity Intervention
How Glutathione Can Save Your Life How Glutathione Can Save Your Life

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map