ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Unravelling the Mysteries of ME/CFS and Fibromyalgia: Meet the Man Behind the Book

How Myofascial Release Got Me Back On My Feet Again

16 Tips from 16 Years Sick

NIH announces centers for myalgic encephalomyelitis/chronic fatigue syndrome research

Cort Johnson Interviews ME/CFS Victor Martha Kilcoyne

Caregivers Draw Support By Mapping Their Relationships

Pediatric Chronic Pain: Prevalence, economic impact, and its relevance to the current opioid epidemi...

Ten Years with ME. This One May Take the Cake

Three NIH Funded ME/CFS Research Centers….and (What Else?) a Controversy

How Physical Therapists are Getting it About Chronic Fatigue Syndrome (ME/CFS)

 
Print Page
Email Article

Increased Levels of IL-17A Found in Patients with Fibromyalgia

  [ 6 votes ]   [ Discuss This Article ]
www.ProHealth.com • September 22, 2013


Editor's comment: Interleukin-17A ( IL-17A) is a proinflammatory cytokine produced by activated T cells.  High levels of  IL-17A are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. 

Increased levels of IL-17A in patients with fibromyalgia.

By A. Pernambuco, et al.

Abstract:

OBJECTIVES: The aim of this study was to evaluate the plasma levels of IL-17A in fibromyalgia patients, and to look for any correlations between this data and the concentrations of some pro- and anti-inflammatory cytokines.

METHODS: We performed a study including 58 fibromyalgia patients and 39 healthy women matched for age and body mass index. The plasma levels of IL-17A and other pro- and anti-inflammatory cytokines were measured by using the technique of cytometric bead array (CBA). The analysis of differences between groups was performed using Mann-Whitney test and the analysis of the correlations by Spearman's correlation test.

RESULTS: The analyses showed that fibromyalgia patients present increased levels of IL-17A. They also revealed that plasma concentrations of IL17A positively correlate with levels of IL-2, IL-4 and IL-10, TNF and IFNγ.

CONCLUSIONS: As far as we are aware, this is the first study to demonstrate increased levels of IL17A in fibromyalgia patients. The positive correlation between the levels of IL-17A and of other cytokines strengthens the hypothesis of the involvement of inflammatory mechanisms in the development of this syndrome.

Source: Clinical and Experimental Rheumatology, September 10, 2013. By A. Pernambuco, L. Schetino, C. Alvim, C. Murad, R. Viana, L. Carvalho and D. Reis. Department of Morphology, Institute of Biological Science, Federal University of Minas Gerais, Brazil.





Post a Comment

Featured Products From the ProHealth Store
B-12 Extreme™ MitoQ® Ultra ATP+, Double Strength


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 Your Brain Needs for Detox & Sharpness
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History
When a Negative is Positive - Goodnighties Recovery Sleepwear When a Negative is Positive - Goodnighties Recovery Sleepwear
The Surprising Benefits of Probiotics - What You Didn't Know The Surprising Benefits of Probiotics - What You Didn't Know
Astaxanthin - A Little-Known but Power-Packed Nutrient Astaxanthin - A Little-Known but Power-Packed Nutrient
The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map