ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|

Trending News

The END ME/CFS Project

The CFS/ME Brain Is Inflamed

Treating Immune Dysfunction in ME/CFS

Ask the Doctor: What Are Your Favorite Treatments for ME/CFS?

Tryptophan depletion in chronic fatigue syndrome, a pilot cross-over study

High-Throughput Sequencing of Plasma MicroRNA in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis

Epigenetics & immune dysfunction in ME/CFS

Inflammatory and oxidative and nitrosative stress cascades as new drug targets in myalgic encephalom...

Use of single-nucleotide polymorphisms (SNPs) to distinguish gene expression subtypes of chronic fat...

Call to Action: Include Ampligen in the 21st Century Cures Legislation!

 
Print Page
Email Article

Fibromyalgia Patients Have High Levels of TNF-a but No Circadian Variation

  [ Not Yet Rated ]   [ Discuss This Article ]
www.ProHealth.com • October 16, 2013


Note: You may read the full text of this article free HERE.

Lack of Circadian Pattern of Serum TNF-α and IL-6 in Patients with Fibromyalgia Syndrome.

By Ghizal Fatima, et al.

Abstract:


The present study was designed to test the hypothesis of a circadian [recurring naturally on a twenty-four-hour cycle] variation in circulating levels of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in women with fibromyalgia syndrome (FMS).

Serum levels of IL-6 and TNF-α were measured at 4  h intervals of the day in 50 women with FMS satisfying American College of Rheumatology criteria for FMS (age 36.68  ±  9.89) as well as 50 healthy control women (age 32.82  ±  10.53).

  • Serum TNF-α levels were substantially increased in patients with FMS but showed no circadian variation.

  • In contrast, no difference in the levels of IL-6 was found.

  • Moreover, there was also no circadian variation in both the groups of patients and controls.

We conclude that no circadian pattern exists in the circulating levels of serum IL-6 and TNF-α in patients with FMS, although TNF-α levels are found raised in patients with FMS.

Source: Indian Journal of Clinical Biochemistry, October 2012. By Ghizal Fatima, Abbas Ali Mahdi, Siddharth Kumar Das, Baby Anjum, Nar Singh Verma, Puneet Kumar, and Ragini Shrivastava. Department of Rheumatology & Biochemistry, Chhatrapati Shahu.



Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Protecting Our Eyes Against Time-Induced Damage Protecting Our Eyes Against Time-Induced Damage
The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health
Live Longer: Groundbreaking Research on Omega-3s Live Longer: Groundbreaking Research on Omega-3s
Running on Empty? Fuel Up with NADH Running on Empty? Fuel Up with NADH
Repair Damaged Mitochondria and Reduce Fatigue Up to 45% Repair Damaged Mitochondria and Reduce Fatigue Up to 45%

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing