ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|

Trending News

The Muscle-Brain Connection in ME/CFS Revealed

The Neurobiology of ME/CFS

Interview: Jennifer Brea Talks About Obstacles, Adjustments, and Inspiration

DNA Methylation Modifications Associated with Chronic Fatigue Syndrome

Adrenal Burnout? Naturally Boost Your Energy & Manage Stress

Smartphone app and specialised clinic for chronic fatigue patients

Curcumin Made 65X More Bioavailable - Modern Take on a "Golden" Spice Busts Brain Fog, Joint & Body ...

Post-Exertional Debility is an Important Symptom during Myalgic Encephalomyelitis

VIDEO: Dr. Newton Talks About Biomarkers and the Future of ME/CFS Treatment

Stress management skills, cortisol awakening response, and post-exertional malaise in Chronic Fatigu...

 
Print Page
Email Article

Low DHEA-S Linked to Increased Pain Sensitivity in Post-Menopausal Women with Fibromyalgia

  [ 52 votes ]   [ Discuss This Article ]
www.ProHealth.com • January 14, 2013


Low DHEA-S Linked to Increased Pain Sensitivity in Post-Menopausal Women with FibromyalgiaArticle:

Influence of cortisol and DHEA-S on pain and other symptoms in post menopausal women with fibromyalgia.

– Source: Journal of Back and Musculoskeletal Rehabilitation , January, 2012.

By Rodrigo Pegado de Abreu Freitas, et al.


Abstract :

Objective: This study aims to assess cortisol and dehydroepiandrosterone sulfate (DHEA-S) levels in post-menopausal women with FMS and correlate it with pain threshold and tolerance, depression and quality of life.

Methods: We conducted a cross sectional observational study of 17 women with FMS (FMS group), and 19 healthy volunteers (CT group). Algometry, the Beck Depression Index (BDI) and Fibromyalgia Impact Questionnaire (FIQ) were used. Blood samples were collected in the morning (8:00–9:30 am) to determine cortisol and DHEA-S plasmatic levels by chemiluminescence.

Results:
Significant differences between groups were recorded for pain threshold and tolerance (p< 0.0001), BDI (p< 0.0001) and all FIQ parameters (p< 0.0001).

No significant differences in cortisol levels were found between the two groups (p=0.325).

In the FMS group, a tangential effect was observed for DHEA-S (p=0.094) and positive correlations were found between DHEA-S, pain threshold (p=0.017) and pain tolerance (p=0.044).

No correlation was observed between cortisol and DHEA-S levels and the variables of depression and quality of life for either group.

Conclusions: There seems to be an influence of the decreased levels of DHEA-S and increased pain sensitivity in post-menopausal women with FMS.


Source:
Journal of Back and Musculoskeletal Rehabilitation , January, 2012. By Rodrigo Pegado de Abreu Freitas – Department of Physiology – Graduate Program in Psychobiology, Federal University of Rio Grande do Norte, Natal, Brazil; Telma Maria Araújo Moura Lemos – Department of Clinical Analysis and Toxicology, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal, Brazil; Maria Helena Constantino Spyrides – Department of Statistics, Federal University of Rio Grande do Norte, Natal, Brazil; Maria Bernardete Cordeiro de Sousa – Department of Physiology – Graduate Program in Psychobiology, Federal University of Rio Grande do Norte, Natal, Brazil.




Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Your Next Order

Featured Products

B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Three-Step Strategy to Reverse Mitochondrial Aging Three-Step Strategy to Reverse Mitochondrial Aging
The Brain Boosting and Fatigue Fighting B-12 The Brain Boosting and Fatigue Fighting B-12
Sleep Like a Baby in Nature's Cradle Sleep Like a Baby in Nature's Cradle
Natural Support for Mood, Sleep and Mental Focus? L-theanine Natural Support for Mood, Sleep and Mental Focus? L-theanine
Protecting Our Eyes Against Time-Induced Damage Protecting Our Eyes Against Time-Induced Damage

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing