Activate Now
 
ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

ACTION ALERT: Telling Your Chronic Pain Story Now is Important

Migraine, Fibromyalgia and ME/CFS

Daily Non-Negotiables for Life with Chronic Illness

Where Is Your Journey Taking You?

Cognition and Chronic Fatigue Syndrome (ME/CFS): Key Findings and Seminal Papers

Living with Purpose

An ME/CFS and FM Recovery Story

#MillionsMissing: A Day of Global Protest

The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS

SURVEY RESULTS: Should Opioids Be Restricted for Chronic Illness?

 
Print Page
Email Article

Acylated ghrelin: A potential marker for fibromyalgia?

  [ 9 votes ]   [ Discuss This Article ]
By D. Homann, et al. • www.ProHealth.com • March 20, 2013


– Source: European Journal of Pain, March 8, 2013

Editor's note:  Acylated ghrelin is the active form of ghrelin, a gastrointestinal hormone which is a strong stimulant of growth hormone from the anterior pituitary. 

Abstract:

BACKGROUND: Fibromyalgia is characterized by chronic widespread pain and sleep disturbances. Overweight and obesity, which lead to metabolic changes, are additional comorbidities that are rarely explored, although they are highly prevalent in patients with fibromyalgia.

METHODS:
We compared the plasma levels of leptin and acylated ghrelin in 17 women with fibromyalgia (patients) and 16 healthy women (controls) with similar age, anthropometric measurements and levels of physical activity. We also investigated the relationships between these two neuropeptides and sleep and various pain characteristics in patients with fibromyalgia. Anthropometric measurements were recorded, and physical activity levels were assessed using a questionnaire. Pain intensity was measured using visual analogue scales (weekly general and mean pain scores). Sleep was assessed using an accelerometry technique.

RESULTS:

  • Compared to the control group, the patient group had increased leptin levels (patients: 22.4?±?10.6 vs. controls: 13.3?±?17.9?ng/mL; p?

  • The leptin level was not significantly correlated with any of the variables.

  • Acylated ghrelin level was inversely correlated with the weekly mean pain score (r?=?-0.67, p?

  • Multiple regression analysis revealed that the variations in acylated ghrelin levels accounted for 35% of the weekly general pain and 29% of the weekly mean pain variability.

CONCLUSIONS: These findings indicate that the decreased acylated ghrelin levels in women with fibromyalgia are related to pain intensity.


Source: European Journal of Pain, March 8, 2013. D. Homann, F.M. Louzada, S.M. Góes, S. Roizenblatt, A.L. Lopes, A.R. de Oliveira, N. Leite. Department of Physical Education, Universidade Federal do Paraná, Curitiba, Brazil.





Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg B-12 Extreme™ MitoQ®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Dr Axe Bone Broth Proteins

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth

Natural Remedies

Coconut Oil - Healthy Gifts from the 'Tree of Life' Coconut Oil - Healthy Gifts from the 'Tree of Life'
Why Berries Offer a Rainbow of Health Benefits Why Berries Offer a Rainbow of Health Benefits
Sunshine Vitamin Has D-lightful Health Benefits Sunshine Vitamin Has D-lightful Health Benefits
Fatigue & Fibro Fog: Could You Have a B-12 Deficiency? Fatigue & Fibro Fog: Could You Have a B-12 Deficiency?
The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map