Activate Now
 
ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

May 12th is International ME/CFS, Lyme, and FM Awareness Day!

Are You ‘Activated’? Mast Cell Activation Syndrome and ME/CFS/FM

A Path Of Emotional Growth

What Are You Looking Forward To?

Peace and Illness: Becoming Comfortable with the Uncomfortable

ME/CFS in Children

3 Ways to Support Your Spouse When You're Chronically Ill

Low Dose Naltrexone - An Effective Treatment for ME/CFS?

You Can Change Your Mind

An Eye on "The Mitochondria Man": Robert Naviaux and Chronic Fatigue Syndrome (ME/CFS)

 
Print Page
Email Article

Quality of Life for Fibromyalgia Patients Worsens after Taking Antidepressants for a Year

  [ 5 votes ]   [ 1 Comment ]
www.ProHealth.com • September 9, 2013


Editor's comment: This was a very small observational study. Just 18 patients completed the study and only seven of those were in the group taking antidepressants (five took an SNRI and two took an SSRI). However, the finding that these patients' quality of life worsened when taking antidepressants for a year is concerning – especially since two of the three drugs approved by the FDA for treating fibromyalgia are SNRI antidepressants.  Additional larger studies are warranted.

Note: You may read the full text of this article free HERE.


The Use of Antidepressants in the Long-Term Treatment Should not Improve the Impact of Fibromyalgia on Quality of Life
Abstract:

Background: Antidepressant (AD) drugs are effective in the short term treatment of fibromyalgia (FM). It may be useful to study the long-term impact of AD on patients with FM.

Methods: One-year follow-up study on 23 females with FM divided into groups on AD (ADg-N=7), and not taking AD (NADg-N=11). Evaluation at t1 and at the end (t2) with the Fibromyalgia Impact Questionnaire (FIQ); at t2 with: SCID-IV; Mood Disorder Questionnaire (MDQ); Short Form-12; Hamilton Depression Rating Scale (HAM-D); Functioning Assessment Short Test (FAST)

Results:

  • After a year the AD group showed a worst impact of the disease by FIQ (p=0.017),

  • worsened quality of life by SF-12 (p<0.01),

  • and disability linked to bipolar symptoms by FAST (p=0.05).

  • About 40% of the sample was screened positive at MDQ without difference in the two groups.

  • The patients who recovered from a depressive episode did not differ between ADg and NADg (20% vs 33.3%), and were fewer than expected from the literature (40-60%).

  • The HAM-D score at the end of the trial was worse in the ADg (p<0.03).

Limitations: Observational research on few patients, not specifically designed to test the hypothesis. The results have a heuristic value only.

Discussion: The results should be read in the light of the high prevalence of patients screened positive for Bipolar Disorders and of the well-known poor response of the mood symptoms to antidepressants in Bipolar Depression. The deterioration in the long-term management of FM patients following AD treatments suggests the need for new and robust studies.

Source: Clinical Practice and Epidemiology in Mental Health, July 12, 2013. By M.G. Carta,, V. Ruggiero, F. Sancassiani, F. Cutrano, A.R. Manca, M. Peri, A. Fais, and E. Cacace. Dipartimento di Sanità Pubblica e Medicina Clinica e Sperimentale, Università di Cagliari e Center of Liaison Psychiatry and Psychosomatics, University Hospital of Cagliari, Italy.





Post a Comment

Featured Products From the ProHealth Store
MitoQ® Hydroxocobalamin Extreme™ B-12 Extreme™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments Post a Comment

Quality of Life after Antidepressents
Posted by: bfmanning
Sep 29, 2013
This is scary as heck! I certainly hope that more studies are done very soon about this.

I am just getting ready to try Cymbalta. I had a horrible reaction to Lyrica--though it helped pain tremendously.

This information in this study, even though about a very small study, makes me extremely reluctant to try Cymbalta or Savella.

Reply Reply
 
20 Helpful Tips for Cleaning and Organizing When You're Chronically Ill

Featured Products

MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 Your Brain Needs for Detox & Sharpness

Natural Remedies

Could a B-12 Deficiency Be Causing Your Symptoms? Could a B-12 Deficiency Be Causing Your Symptoms?
Sunshine Vitamin Has D-lightful Health Benefits Sunshine Vitamin Has D-lightful Health Benefits
Complete and Natural Menopause Relief Complete and Natural Menopause Relief
Safely Burn Away Body Fat Safely Burn Away Body Fat
Physically and Mentally Exhausted? How to Restore Energy at Its Source Physically and Mentally Exhausted? How to Restore Energy at Its Source

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler

· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map