ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Response to vitamin B12 and folic acid in myalgic encephalomyelitis and fibromyalgia.

ADHD (Attention Deficit Hyperactivity Disorder) May Be Common in Fibromyalgia

Be Your Own Researcher: Treat Chronic Pain as a Daily Experiment

You Can Use Mindfulness to Choose How to Live

NEID Disease? Study Suggests Neuro, Endocrine and Immune Systems Work Together to Produce ME/CFS

The Depression Puzzle: Are Anti-inflammatories Better Than Antidepressants? An ME/CFS and FM Perspec...

Is Acceptance Just Resignation?


Improvement of severe myalgic encephalomyelitis/chronic fatigue syndrome symptoms following surgical...

Eukaryotes in the gut microbiota in myalgic encephalomyelitis/chronic fatigue syndrome

Print Page
Email Article

Selenium intake reduces serum C3, an early marker of metabolic syndrome manifestations, in healthy young adults – Source: European Journal of Clinical Nutrition, Nov 5, 2008

  [ 38 votes ]   [ Discuss This Article ]
By B Puchau, JA Martinez, et al. • • November 21, 2008

[Note: Metabolic syndrome – believed to affect up to 25% of the US population - is a combination of disorders that raise the risk of developing diabetes and cardiovascular disease (high blood pressure, central body obesity, low ‘good’ HDL cholesterol, high triglycerides, blood sugar regulation problems). Selenium is a micronutrient necessary for cellular function and antioxidant enzyme production, found in plant foods/meats/nuts, depending on selenium content of soil. The full text of this article is available free at the EJCN site.]

Objectives: To evaluate the associations between serum complement factor 3 (C3) and several anthropometrical, biochemical and lifestyle features in healthy young adults, emphasizing on the putative effect of selenium intake on C3 concentrations.

Methods: This study enrolled 100 healthy young adults aged 18 to 34 years. Anthropometric and blood pressure measurements and lifestyle features were analyzed. Fasting blood samples were collected for the measurement of glucose, total cholesterol, HDL-cholesterol, LDL-cholesterol, triacylglycerols and C3 concentrations. Nail samples were collected for the analysis of selenium concentrations.

Results: Values of BMI (P=0.034), sum of skinfold thicknesses (STs) (P=0.021), body fat mass (BFM) (P=0.023), percentage of overweight subjects (P=0.007), serum triacylglycerols (P=0.012) and nail selenium (P=0.001) were significantly different between subjects above and below the median of serum C3 concentrations. The following correlations with serum C3 were identified tricipital ST (P=0.033), sum of STs (P=0.012), BMI (P=0.008), BFM (P=0.018), waist-to-height ratio (P=0.016), serum glucose (P=0.045), serum triacylglycerols (P=0.001) and nail selenium (P=0.006). Circulating C3 showed a positive association with several adiposity markers such as BMI (P=0.001), waist circumference (P=0.006), waist-to-height ratio (P=0.002), BFM (P=0.025), as well as serum glucose (P=0.027) and triacylglycerols (P<0.001), whereas nail selenium was a statistically significant negative predictor of C3 concentrations (P=0.018).


• C3 seems to be related with selenium status and several anthropometrical and biochemical measurements linked to metabolic syndrome in apparently healthy young adults.

• These findings suggest a possible role for selenium intake in the modulation of C3, whose assessment may be an early marker of metabolic syndrome manifestations.

Source: European Journal of Clinical Nutrition, Nov 5, 2008 [E-pub ahead of print] PMID: 18985060, by Puchau B, Zulet MA, Gozalez de Echavarri A, Navarro-Blasco I, Martinez JA. Department of Nutrition and Food Sciences, Physiology and Toxicology and Department of Chemistry and Soil Science, University of Navarra, Pamplona, Spain. [E-mail: Dr. JA Martinez,]

Post a Comment

Featured Products From the ProHealth Store
Hydroxocobalamin Extreme™ Energy NADH™ 12.5mg Mitochondria Ignite™ with NT Factor®

Article Comments

Be the first to comment on this article!

Post a Comment

Optimized Curcumin Longvida with Omega-3

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 Your Brain Needs for Detox & Sharpness
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get Energized with Malic Acid & Magnesium

Natural Remedies

The Remarkable Benefits of Reishi Medicinal Mushrooms The Remarkable Benefits of Reishi Medicinal Mushrooms
"It's Not Easy Being Green" - But It Is Healthy
Breaking Through the Mental Fog Breaking Through the Mental Fog
When a Good Night's Sleep Is Just a Daydream... When a Good Night's Sleep Is Just a Daydream...
Block Acid Reflux to Prevent Esophageal Problems! Block Acid Reflux to Prevent Esophageal Problems!

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2018 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map