Activate Now
 
ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

15 tips for cooking and cleaning your kitchen when you’re chronically ill

When the Joy Just Isn’t Getting Through

The New Dual Activation Pain Relief Cream

20 Date Night Ideas for Chronic Illness

Microstructural Havoc: The Immune System, Fatigue and the Brain - An ME/CFS and FM Scenario

SURVEY RESULTS: Medical Marijuana

Ketamine: Wonder Drug?

May 12th is International ME/CFS, Lyme, and FM Awareness Day!

What You Need to Know About How Your Tasty “Bliss Point” Affects Your Chronic Illness

A Path Of Emotional Growth

 
Print Page
Email Article

Growth hormone treatment for sustained pain reduction and improvement in quality of life in severe fibromyalgia - Source: Pain, Mar 30, 2012

  [ 10 votes ]   [ 1 Comment ]
By Guillem Cuatrecasas, et al. • www.ProHealth.com • April 5, 2012


[Note: Insulin-like growth factor 1 (growth hormone) helps maintain muscle tissue. Most growth hormones are secreted during the deep sleep cycle, so it is important to reach this restorative sleep phase for healthy levels of IGF-1. Recent research indicating sodium oxybate (Xyrem) may help fibromyalgia symptoms could be owing to an ability to stimulate release of growth hormone. See for example “Sodium oxybate for the treatment of fibromyalgia,” Jun 16, 2011, by Roland Staud at the University of Florida.]

Functional defects in growth hormone (GH) secretion and its efficacy as a complementary treatment have been suggested for fibromyalgia.

This study investigated the efficacy and safety of low-dose GH as an add-on therapy in patients with both severe FM and low insulin-like growth factor 1 levels.

A total of 120 patients were enrolled in a multicenter, placebo-controlled study for 18 months.

• They were randomly assigned to receive either 0.006mg/kg/day of GH subcutaneously (group A, n=60) or placebo (group B, n=60) for 6 months (blind phase).

• The placebo arm was switched to GH treatment from month 6 to month 12 (open phase),

• And a follow-up period after GH discontinuation was performed until month 18.

Standard treatment for fibromyalgia (selective serotonin re-uptake inhibitors, opioids, and amitriptyline) was maintained throughout the study.

Number and intensity of tender points, Fibromyalgia Impact Questionnaire (FIQ) with its subscales, and EuroQol 5 dimensions test (EQ5D) with visual analog [pain] scale (VAS) were assessed at different time points. At the end of the study [6 months after therapy ended]:

• 53% of group A patients [who received GH for 12 months] obtained fewer than 11 positive tender points, vs 33% of group B patients [who received GH from months 7 -12] (P<.05).

• 39.1% vs 22.4% reached more than 50% improvement in VAS (P<.05). [The VAS pain scale measures pain by color, descriptions, and numbers 1-10, from 'none' (0) to 'agonizing' (10).]

• Group A patients showed significantly improved FIQ scores (P=.01) compared with group B.

Although GH discontinuation worsened all scores in both groups during follow-up, impairment in pain perception was less pronounced in the GH-treated group [who received it for 12 months](P=.05).

In this largest and longest placebo-controlled trial performed in FM (NCT00933686), addition of GH to the standard treatment is effective in reducing pain, showing sustained action over time.

Source: Pain, Mar 30, 2012. Cuatrecasas G, Alegre C, Fernandez-Solà J, Gonzalez MJ, Garcia-Fructuoso F, Poca-Dias V, Nadal A, Cuatrecasas G, Navarro F, Mera A, Lage M, Peinó R, Casanueva F, Liñan C, Sesmilo G, Coves MJ, Izquierdo JP, Alvarez I, Granados E, Puig-Domingo M. Endocrinology Department Centro Médico Teknon and Clinica Sagrada Familia, Barcelona, Spain.
 





Post a Comment

Featured Products From the ProHealth Store
B-12 Extreme™ MitoQ® Mitochondria Ignite™ with NT Factor®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments Post a Comment

Cost/Benefit
Posted by: KerryK
Apr 5, 2012
The benefits of GH in this study appear to be modest, as is true of the other option. However, I understand that GH is very expensive so it is hard to imagine that it could ever be a common treatment.
Reply Reply
 
20 Helpful Tips for Cleaning and Organizing When You're Chronically Ill

Featured Products

MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 Your Brain Needs for Detox & Sharpness
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Natural Support for Mood, Sleep and Mental Focus? L-theanine Natural Support for Mood, Sleep and Mental Focus? L-theanine
Looking for Energy? Turn to Plants. Looking for Energy? Turn to Plants.
Coenzyme Q10 - The Energy Maker Coenzyme Q10 - The Energy Maker
Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance
Red Yeast Rice - Natural Option for Supporting Healthy Cholesterol Red Yeast Rice - Natural Option for Supporting Healthy Cholesterol

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler

· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map