ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|

Trending News

A Commercially Available Probiotic Reduces Chronic Fatigue Syndrome’s Inflammation—Should we offer t...

SURVEY RESULTS: What Name Would YOU Choose for CFS?

Simmaron’s Spinal Fluid Study Finds Dramatic Differences in Chronic Fatigue Syndrome

Cell-Charging Compound Gives Steady Energy to Fibromyalgia & Chronic Fatigue Patients

The Countess of Mar, Medical Politics, and ME/CFS

What were your first symptoms of ME/CFS?

Life for a Young Person with M.E.

ProHealth's 2014 Advocate of the Year – Ryan Prior

Cultivating Self-Compassion

Autoimmune Organization Makes Urgent Call For Fatigue Research

 
Print Page
Email Article

Magnesium intake and risk of colorectal cancer: A meta-analysis of prospective studies – Source: European Journal of Clinical Nutrition, Oct 3, 2012

  [ 4 votes ]   [ Discuss This Article ]
By GC Chen, et al. • www.ProHealth.com • October 16, 2012


[Note: This analysis of 338,979 adults whose relative dietary magnesium intake & health was tracked (8 well-designed prospective studies) found an average 19% reduction in risk of colon cancer among those in the highest-magnesium intake group vs. those with lowest intake, and 6% lower risk for rectal cancer. See the NIH Office of Dietary Supplements Magnesium site for info on dietary sources, RDAs, deficiency risk factors and related health problems.]

Abstract:
Epidemiologic studies have suggested that magnesium intake may be associated with a decreased risk of colorectal cancer (CRC), but the findings have been inconsistent. We aimed to assess this association by conducting a meta-analysis of prospective studies.

We performed a literature search on PubMed database through July 2012 to identify prospective studies of magnesium intake in relation to CRC risk. Reference lists of the retrieved articles were also reviewed. A random-effects model was used to compute the summary risk estimates. Eight prospective studies containing 338,979 participants and 8,000 CRC cases met the inclusion criteria.

The summary relative risk (RR) for the highest vs lowest category of magnesium intake for CRC was 0.89 (95% CI, 0.79-1.00), with little evidence of heterogeneity. Restricting the analysis to six studies that have adjusted for calcium intake yielded a similar result.

For colon and rectal cancer, the pooled RR was 0.81 (95% CI, 0.70-0.93) and 0.94 (95% CI, 0.72-1.24), respectively. [Note: a risk ratio of 1.0 would indicate no difference in average risk; accordingly, the RR of 0.81 indicates a 19% reduction of risk in the highest Mg group.]

In the dose-response analyses, the summary RRs for an increment of magnesium intake of 50mg/day for colorectal, colon and rectal cancer were, respectively, 0.95 (95% CI, 0.89-1.00), 0.93 (95% CI, 0.88-0.99) and 0.93 (95% CI, 0.83-1.04), and there was some evidence of heterogeneity; omitting one study that substantially contributed to the heterogeneity yielded generally similar results, but with low heterogeneity. We detected no indication of publication bias.

On the basis of the findings of this meta-analysis, a higher magnesium intake seems to be associated with a modest reduction in the risk of CRC, in particular, colon cancer.

Source: European Journal of Clinical Nutrition, Oct 3, 2012. PMID:23031849, by Chen GC, Pang Z, Liu QF. Department of Epidemiology, School of Public Health, Soochow University, Suzhou, China.




Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth

Natural Remedies

Quercetin: Natural Support for Allergy & Inflammation Relief and More Quercetin: Natural Support for Allergy & Inflammation Relief and More
Eating Fat is Good… Maybe… Could Be… Sometimes Eating Fat is Good… Maybe… Could Be… Sometimes
Milk Thistle: Trusted Support for Health & Healing in a Toxic World Milk Thistle: Trusted Support for Health & Healing in a Toxic World
Help for Soreness and Swelling: What Do Silkworms Have to Do With It? Help for Soreness and Swelling: What Do Silkworms Have to Do With It?
Coping When Colds or Flu Catch Up with You

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing