ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

The New Me

When Retreat Means Advance: A Recovered Chronic Fatigue Syndrome/Fibromyalgia Patient Looks Back

Creating Intimacy Through Mindful Touch When You Live with Chronic Illness

VIDEO: How does your brain respond to pain?

4 Ways to Give Back When You’re Chronically Ill

Millions Missing Day of Protest Draws Attention to Plight of ME/CFS Patients All Over the Globe

10 Fibro-Friendly Foods with a Bonus: Beautiful Skin

An Illness Denied for Decades Is Exposed - Lighting Up a Hidden World: CFS and ME

Fight Back! Win the War Being Waged Against Your Immune System

Studies Show that Magnesium L-threonate Improves Brain Plasticity, Leading to Direct and Significant...

Print Page
Email Article

Sleep in chronic fatigue syndrome

  [ 6 votes ]   [ 1 Comment ]
By An N. Marimana et al. • • April 30, 2013

Editor's Comment: Numerous studies have found abnormalities in brain wave patterns in CFS/ME patients during sleep, including alpha spikes (micro-awakenings), excess theta wave production (light sleep), lower ratio of stage 4 sleep (deep sleep), increased IL-10 (an anti-inflammatory cytokine that promotes wakefulness), as well as phase-shifting (falling asleep at dawn), sleep apnea (cessation of breathing), and myoclonus (jerks). Most CFS/ME specialists rank treatment of the CFS/ME sleep disorder among their priorities.

By An N. Marimana et al.


Chronic fatigue syndrome (CFS) is a disabling condition characterized by severe fatigue lasting for more than six months and the presence of at least four out of eight minor criteria. Sleep disturbance presenting as unrefreshing or nonrestorative sleep is one of these criteria and is very common in CFS patients.

Biologically disturbed sleep is a known cause of fatigue and could play a role in the pathogenesis of CFS. However, the nature of presumed sleep impairment in CFS remains unclear. Whilst complaints of NRS persist over time, there is no demonstrable neurophysiological correlate to substantiate a basic deficit in sleep function in CFS.

Polysomnographic findings have not shown to be significantly different between subjects with CFS and normal controls. Discrepancies between subjectively poor and objectively normal sleep suggest a role for psychosocial factors negatively affecting perception of sleep quality.

Primary sleep disorders are often detected in patients who otherwise qualify for a CFS diagnosis. These disorders could contribute to the presence of daytime dysfunctioning.

There is currently insufficient evidence to indicate that treatment of primary sleep disorders sufficiently improves the fatigue associated with CFS. Therefore, primary sleep disorders may be a comorbid rather than an exclusionary condition with respect to CFS.

Source: Sleep Medicine Reviews, Volume 17, Issue 3 , Pages 193-199, June 2013. An N. Marimana, Dirk P. Vogelaersa, Els Tobbacka, Liesbeth M. Delesiea, Ignace P. Hanoullea, Dirk A. Pevernagieb.

Post a Comment

Featured Products From the ProHealth Store
B-12 Extreme™ Mitochondria Ignite™ with NT Factor® MitoQ®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments Post a Comment

False premises
Posted by: polycarpuk
Oct 13, 2013
I object to several things about this article.

Firstly starting with the definition of CFS/ME as fatigue plus 4 out of 8 minor symptoms. We have come a long way since this was a reasonable definition and describing everything other than fatigue as minor symptoms is insulting. To many of us the fatigue is a minor symptom and other symptoms are more disabling day by day. 24/7 muscular and joint pain for instance is NOT minor.

Secondly is a logical fallacy. The presumption that disturbed sleep, if not a cause of CFS/ME, must therefore be an unrelated comorbid condition. Why cannot disturbed sleep be another symptom, not a cause of CFS/ME but a result of CFS/ME. Personally I have the comorbid condition congestive sleep apnea, but treatment of this condition using a CPAP machine made no difference to my disturbed sleep pattern whatsoever, or my fatigue!

The author needs to go back, read the Canadian Criteria, take time to understand that CFS/ME is an extremely complex condition, and then try research that would actually add to the sum of human knowledge, which this article and the 'research' behind it, most definitely do not.
Reply Reply
Natural Pain Relief Supplements

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Studies Show that Magnesium L-threonate Improves Brain Plasticity, Leading to Direct and Significant Improvements in Memory, Learning, and Cognition.3 Studies Show that Magnesium L-threonate Improves Brain Plasticity, Leading to Direct and Significant Improvements in Memory, Learning, and Cognition.3
Improve Cardiovascular and Metabolic Health with Omega-7 Improve Cardiovascular and Metabolic Health with Omega-7
Guarding Against the Dangers of Vitamin D Deficiency Guarding Against the Dangers of Vitamin D Deficiency
Research Links Green Tea to Weight Loss Research Links Green Tea to Weight Loss
How Glutathione Can Save Your Life How Glutathione Can Save Your Life

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map