ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

“Medical Game-Changer” To Shed New Light on Neuroimmune Diseases

The ME Association Illness Management Report: “No decisions about me, without me”

Phase II Cyclophosphamide trial for ME gets under way

5 Tips for When Motivation Runs Out

Tipping Point? The Stanford Chronic Fatigue Initiative’s Big Year Is Here

There's This Friend I Have...

VIDEO: Dr. Light Compares Fatigue in ME/CFS to Cancer, MS, and Fibromyalgia

Neuro-inflammation II: The Kynurenine Pathway in Fibromyalgia and ME/CFS

Powerful Anti-Herpes Drug Moves Forward: Hope for ME/CFS/FM Patients

Chronic fatigue syndrome and increased susceptibility to upper respiratory tract infections and illn...

 
Print Page
Email Article

Characteristics of Sensitization in Fibromyalgia, IBS and TMD

  [ 4 votes ]   [ Discuss This Article ]
www.ProHealth.com • May 17, 2013


Characteristics of Sensitization Associated With Chronic Pain Conditions.

By Charles J. Vierck, PhD, et al.

Abstract:

OBJECTIVES: To describe and understand varieties and characteristics of sensitization contributing to hyperalgesia in participants with chronic pain conditions.

METHODS: Thermal stimulation was delivered to the face, forearm, and calf of pain-free participants and individuals with irritable bowel syndrome, temporomandibular pain disorder (TMD), and fibromyalgia syndrome (FM). Three-second contacts by a preheated thermode occurred at 30-second intervals in ascending and then in descending series (0.7°C steps).

RESULTS:

  • Thermal pain ratings during ascending series were greater at each site in individuals diagnosed with chronic pain.

  • Intense pain at the time of testing further enhanced the ratings at all sites, but mild or moderate clinical pain did not have this effect.

  • Thermal pain in all participants was greater during descending series compared with the ascending series of arm and leg stimulation.

  • The hypersensitivity during the descending series was comparable in pain-free, FM and TMD participants but was increased in duration for arm or leg stimulation of FM participants.

DISCUSSION: The widespread sensitization for irritable bowel syndrome and TMD participants does not rely on mechanisms of spatial and temporal summation often invoked to explain widespread hyperalgesia associated with chronic pain. Increased sensitivity during descending series of stimulation of an arm or leg but not the face indicates a propensity for sensitization of nociceptive input to the spinal cord. Abnormally prolonged sensitization for FM participants reveals a unique influence of widespread chronic pain referred to deep somatic tissues.

Source: The Clinical Journal of Pain, April 25, 2013. By Charles J. Vierck, PhD, Fong Wong, DDS, Christopher D. King, PhD, Andre P. Mauderli, DMD, PhD, Siegfried Schmidt, MD, PhD and Joseph L. Riley III, PhD. Departments of Behavioral Science Prosthodontics, College of Dentistry Departments of Community Health and Family Medicine Neuroscience, College of Medicine, University of Florida, Gainesville, FL.




Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria

Natural Remedies

Curcumin - a Golden Gift of Nature with Benefits Still Untold Curcumin - a Golden Gift of Nature with Benefits Still Untold
Milk Thistle: Trusted Support for Health & Healing in a Toxic World Milk Thistle: Trusted Support for Health & Healing in a Toxic World
When a Good Night's Sleep Is Just a Daydream... When a Good Night's Sleep Is Just a Daydream...
Complete and Natural Menopause Relief Complete and Natural Menopause Relief
Anti-Inflammatory Properties of Tart Cherry Anti-Inflammatory Properties of Tart Cherry

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing