Activate Now
 
ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

15 tips for cooking and cleaning your kitchen when you’re chronically ill

Chronic Illness: You Don’t Get It Until You Get It

When the Joy Just Isn’t Getting Through

20 Date Night Ideas for Chronic Illness

The New Dual Activation Pain Relief Cream

Microstructural Havoc: The Immune System, Fatigue and the Brain - An ME/CFS and FM Scenario

Next Gen Opioid Drugs Promise Pain Relief Without Side Effects

VIDEO: Tired But Wired

Ketamine: Wonder Drug?

What You Need to Know About How Your Tasty “Bliss Point” Affects Your Chronic Illness

 
Print Page
Email Article

Study: Probiotics reduce stress-induced intestinal flare-ups

  [ 3 votes ]   [ Discuss This Article ]
www.ProHealth.com • September 20, 2013


Press Release: University of Michigan Health System, March 13, 2013

ANN ARBOR, Mich. – For those with irritable bowel syndrome who wonder if stress aggravates their intestinal disorder, a new University of Michigan Health System study shows it’s not all in their head.

While stress does not cause IBS, the study revealed it does alter brain-gut interactions and induces the intestinal inflammation that often leads to severe or chronic belly pain, loss of appetite and diarrhea.

Stress has a way of suppressing an important component called an inflammasome which is needed to maintain normal gut microbiota, but probiotics reversed the effect in animal models, according to findings published online ahead of print in Gastroenterology.  

“The effect of stress could be protected with probiotics which reversed the inhibition of the inflammasome,” says senior study author and gastroenterologistJohn Y. Kao, M.D., associate professor of internal medicine at the University of Michigan. “This study reveals an important mechanism for explaining why treating IBS patients with probiotics makes sense.”

Probiotics are live bacteria that help grow the gut-dwelling “good” bacteria that keep pathogens in check, aid digestion and nutrient absorption and contribute to immune function.

U-M researchers including Chung Owyang, M.D., chief of the U-M Division of Gastroenterology, Gary Huffnagle, Ph.D., professor of pulmonary and critical care, and infectious disease expert Vincent Young, M.D., Ph.D., were able to identify the way stress significantly altered the composition of gut bacteria and the role of probiotics.

Maintaining healthy microbiota requires action by nucleotide-binding oligomerization domain protein-like receptors, pyrin-domain containing (NLRP)-6 inflammasomes.  But when stressed, mice produced corticotropin-releasing hormone (CRH) that prevented inflammasomes from doing their job.

Inhibiting inflammosomes alters the composition of the gut, leading to intestinal inflammation. In the study, pretreatment with probiotic therapy reduced inflammation in mice with stress-induced small bowel inflammation.

“Additional clinical study is required to determine the optimal probiotic therapy,” says Kao. “Patients can start living healthier lifestyles to improve their gut microbiota such as adding more fruits and vegetables to their diet, and looking for ways to keep stress in check.”

Reference: “Stress-induced corticotropin-releasing hormone-mediated NLRPG inflammasome inhibition and transmissible enteritis in mice" Gastroenterology, doi: 10.1053




Post a Comment

Featured Products From the ProHealth Store
B-12 Extreme™ Hydroxocobalamin Extreme™ Mitochondria Ignite™ with NT Factor®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Aching for Pain Relief?

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 Your Brain Needs for Detox & Sharpness

Natural Remedies

Live Without Anxiety or Stress
The Guaifenesin Story: A centuries-old bark extract used for clearing the airways – now key to a popular FM symptom-reversal protocol The Guaifenesin Story: A centuries-old bark extract used for clearing the airways – now key to a popular FM symptom-reversal protocol
Block Acid Reflux to Prevent Esophageal Problems! Block Acid Reflux to Prevent Esophageal Problems!
Breaking Through the Mental Fog Breaking Through the Mental Fog
Vitamin K-2 – A Key Player in Cardiovascular and Bone Health Vitamin K-2 – A Key Player in Cardiovascular and Bone Health

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler

· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map