ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Chronic Pain, Loneliness, Depression and Suicide

Things to Do When You're Mostly Housebound

Is a Good Night's Sleep at the Top of Your Wishlist?

When Everybody has a Plan in Life Except You

The Restorative Power of Nature

A Holiday Gift Guide for People with ME/CFS and Fibromyalgia

VIDEO: Dear Healthy People: Identity Crisis

Norwegian Rituximab Chronic Fatigue Syndrome (ME/CFS) Trial Fails

Cardiovascular Characteristics Of Chronic Fatigue Syndrome

Neuroendocrine disorder in chronic fatigue syndrome

 
Print Page
Email Article

Study Identifies 3 Fibromyalgia Subgroups

  [ 11 votes ]   [ Discuss This Article ]
www.ProHealth.com • October 15, 2013


Note: You may read the full text of this article free HERE.

Cluster Analysis of Clinical Data Identifies Fibromyalgia Subgroups.

By Elisa Docampo, et al.

Abstract:

INTRODUCTION: Fibromyalgia (FM) is mainly characterized by widespread pain and multiple accompanying symptoms, which hinder FM assessment and management. In order to reduce FM heterogeneity we classified clinical data into simplified dimensions that were used to define FM subgroups.

MATERIAL AND METHODS: 48 variables were evaluated in 1,446 Spanish FM cases fulfilling 1990 ACR FM criteria. A partitioning analysis was performed to find groups of variables similar to each other. Similarities between variables were identified and the variables were grouped into dimensions. This was performed in a subset of 559 patients, and cross-validated in the remaining 887 patients. For each sample and dimension, a composite index was obtained based on the weights of the variables included in the dimension. Finally, a clustering procedure was applied to the indexes, resulting in FM subgroups.

RESULTS: VARIABLES CLUSTERED INTO THREE INDEPENDENT DIMENSIONS: "symptomatology", "comorbidities" and "clinical scales". Only the two first dimensions were considered for the construction of FM subgroups. Resulting scores classified FM samples into three subgroups:

  • low symptomatology and comorbidities (Cluster 1),

  • high symptomatology and comorbidities (Cluster 2), and

  • high symptomatology but low comorbidities (Cluster 3), showing differences in measures of disease severity.

CONCLUSIONS: We have identified three subgroups of FM samples in a large cohort of FM by clustering clinical data. Our analysis stresses the importance of family and personal history of FM comorbidities. Also, the resulting patient clusters could indicate different forms of the disease, relevant to future research, and might have an impact on clinical assessment.

Source: PloS One, September 30, 2013. By Elisa Docampo, Antonio Colladol, Geòrgia Escaramís, Jordi Carbonell, Javier Rivera, Javier Vidal, José Alegre, Raquel Rabionet and Xavier Estivill. Genomics and Disease Group, Centre for Genomic Regulation (CRG), Barcelona, Spain ; Universitat Pompeu Fabra (UPF), Barcelona, Spain ; Centro de Investigación Biomédica en Red en Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain.





Post a Comment

Featured Products From the ProHealth Store
Mitochondria Ignite™ with NT Factor® Energy NADH™ 12.5mg Hydroxocobalamin Extreme™


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 Your Brain Needs for Detox & Sharpness
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Reversing Neurodegeneration with a New Magnesium Compound Reversing Neurodegeneration with a New Magnesium Compound
Aches and Pains? A Simple Solution You'll Love Aches and Pains? A Simple Solution You'll Love
Stop Bacteria With Nature's Antibiotics Stop Bacteria With Nature's Antibiotics
Herbal Rescue for High Blood Sugar Herbal Rescue for High Blood Sugar
Strengthen Cell Function with Energy-Boosting Niagen Strengthen Cell Function with Energy-Boosting Niagen

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map