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Men with Fibromyalgia Have More Sleep Respiratory Disorders than Women

  [ 2 votes ]   [ 1 Comment ] • February 23, 2014

Editor's comment: After pain and fatigue, poor sleep is one of the most common symptoms of fibromyalgia. Because FM affects a much higher percentage of women than men, most studies focus predominately on women. Researchers in Spain, however, set up a study to compare the sleep difficulties between men and women with fibromyalgia. They found that men with FM had more sleep-related respiratory problems and poorer quality of sleep than women.

Fibromyalgia: gender differences and sleep-disordered breathing.

By G. Prados, et al.


OBJECTIVES: The prevalence of fibromyalgia (FM) is much lower in men than in women. Therefore, current knowledge about this chronic pain syndrome emerged mainly from research on women. The aim of the present study was to compare clinical symptoms and sleep parameters between male and female FM patients.

METHODS: Forty FM patients (18 men and 22 women) aged 48.00±8.45 years were evaluated with questionnaires on pain, sleep, fatigue, depression, anxiety and functional impact, and polysomnography (PSG).

  • 61% of male FM patients had an apnea-hypopnea index (AHI) greater than 15, compared to 31.8% of women,

  • and a desaturation index (DI) above five, which was twice more prevalent in men than in women.

  • In addition, males had poorer sleep quality (16.05±2.92% vs. 13.08±3.88%; p=0.01) and slow wave sleep (SWS) (stage 3 duration: 9.02±7.84% vs. 14.44±7.32%; p=0.03) than women.

  • No differences were found between the two groups in the level of pain, emotional distress, or daily functioning.

  • However, pain in men, fatigue in women, and functional impact in both sexes seemed to be related to worse sleep quality.

  • Also in women, alterations in total sleep time (TST) and rapid eye movement (REM) sleep features appeared to be related to emotional status.

CONCLUSIONS: Alterations in sleep respiratory patterns were more highly prevalent in male than in female FM patients. More so in male FM patients, the alterations in sleep patterns, non-refreshing sleep, and other FM-related symptoms observed in this population might be part of a primary sleep-disordered breathing.

Source: Clinical and Experimental Rheumatology, December 16, 2013. By G. Prados, E. Miró, M. Martínez, A. Sánchez, S. López and G. Sáez. Department of Personality, Assessment and Psychological Treatment, School of Psychology, University of Granada, Granada, Spain/ Internal Medicine Service, Virgen de las Nieves University Hospital, Granada, Spain.

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Article Comments Post a Comment

Posted by: roge
Feb 25, 2014
Interesting study results. I am a male with severe FM and I got 0% in stage 3 and 4 sleep (slow wave sleep). FDA Needs to approve Xyrem (GHB) NOW for FM as this natural molecule ( yes was sold in healthfood stores in the 1990s) is PROVEN TO INCREASE SLOW WAVE SLEEP yet FDA is is withholding this drug from people who desperately need it
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