ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Cultivating Trust to Make your NOW Better

Living Gratitudes: A New Approach to the Gratitude Journal

Help Bring Unrest to a Theater Near You!

Major Stanford Study Indicates Chronic Fatigue Syndrome (ME/CFS) is Inflammatory Disorder

When Our Chronically Ill Bodies Say “Rest,” Why Don't We?

Special issue on the PACE Trial

The Big Fishing Expedition: Report From the NIH Intramural Study on ME/CFS

VIDEO: Dear Healthy People: Are You Feeling Better?

Epigenetics Study Highlights Metabolic Problems in Chronic Fatigue Syndrome (ME/CFS)

OMF Symposium to Provide First Look at Metabolomic / Immune Results in ME/CFS

 
Print Page
Email Article

Acylated ghrelin: A potential marker for fibromyalgia?

  [ 9 votes ]   [ Discuss This Article ]
By D. Homann, et al. • www.ProHealth.com • March 20, 2013


– Source: European Journal of Pain, March 8, 2013

Editor's note:  Acylated ghrelin is the active form of ghrelin, a gastrointestinal hormone which is a strong stimulant of growth hormone from the anterior pituitary. 

Abstract:

BACKGROUND: Fibromyalgia is characterized by chronic widespread pain and sleep disturbances. Overweight and obesity, which lead to metabolic changes, are additional comorbidities that are rarely explored, although they are highly prevalent in patients with fibromyalgia.

METHODS:
We compared the plasma levels of leptin and acylated ghrelin in 17 women with fibromyalgia (patients) and 16 healthy women (controls) with similar age, anthropometric measurements and levels of physical activity. We also investigated the relationships between these two neuropeptides and sleep and various pain characteristics in patients with fibromyalgia. Anthropometric measurements were recorded, and physical activity levels were assessed using a questionnaire. Pain intensity was measured using visual analogue scales (weekly general and mean pain scores). Sleep was assessed using an accelerometry technique.

RESULTS:

  • Compared to the control group, the patient group had increased leptin levels (patients: 22.4?±?10.6 vs. controls: 13.3?±?17.9?ng/mL; p?

  • The leptin level was not significantly correlated with any of the variables.

  • Acylated ghrelin level was inversely correlated with the weekly mean pain score (r?=?-0.67, p?

  • Multiple regression analysis revealed that the variations in acylated ghrelin levels accounted for 35% of the weekly general pain and 29% of the weekly mean pain variability.

CONCLUSIONS: These findings indicate that the decreased acylated ghrelin levels in women with fibromyalgia are related to pain intensity.


Source: European Journal of Pain, March 8, 2013. D. Homann, F.M. Louzada, S.M. Góes, S. Roizenblatt, A.L. Lopes, A.R. de Oliveira, N. Leite. Department of Physical Education, Universidade Federal do Paraná, Curitiba, Brazil.





Post a Comment

Featured Products From the ProHealth Store
MitoQ® Ultra ATP+, Double Strength Mitochondria Ignite™ with NT Factor®


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 Your Brain Needs for Detox & Sharpness

Natural Remedies

SAD? Coping with Seasonal Affective Disorder SAD? Coping with Seasonal Affective Disorder
"It's Not Easy Being Green" - But It Is Healthy
Coping When Colds or Flu Catch Up with You Coping When Colds or Flu Catch Up with You
How Glutathione Can Save Your Life How Glutathione Can Save Your Life
Priming Your Immune System for Cold & Flu Season Priming Your Immune System for Cold & Flu Season

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map