Activate Now
ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Chronic Fatigue Syndrome, Fibromyalgia and Mitchondrial Disorders: A Comparison Plus the MitoQ Trial...

Are All the "Feel-Good" Pathways Blocked in Fibromyalgia and Chronic Fatigue Syndrome?

5 Things I've Learned About Chronic Illness Through Mindfulness

Cellular Havoc: Zeroing In On The Sleep Problems in Fibromyalgia?

Misdiagnosis on a grand scale?

Diagnosing and Managing Mold Exposure

The Pressure We Put Ourselves Under To Find a Way Forward

Strategies for Fighting Depression

Gulf War veterans' health: medical evaluation of a U.S. cohort

The Chokehold Behavioral Treatments Have on Chronic Fatigue Syndrome

Print Page
Email Article

Immunostimulation in the treatment for chronic fatigue syndrome/myalgic encephalomyelitis

  [ 6 votes ]   [ 1 Comment ]
By A. D. Proal et al. • • April 18, 2013

By A.D. Proal  et al.


Chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME) has long been associated with the presence of infectious agents, but no single pathogen has been reliably identified in all patients with the disease. Recent studies using metagenomic techniques have demonstrated the presence of thousands of microbes in the human body that were previously undetected and unknown to science. More importantly, such species interact together by sharing genes and genetic function within communities. It follows that searching for a singular pathogen may greatly underestimate the microbial complexity potentially driving a complex disease like CFS/ME. Intracellular microbes alter the expression of human genes in order to facilitate their survival. We have put forth a model describing how multiple species - bacterial, viral, and fungal - can cumulatively dysregulate expression by the VDR nuclear receptor in order to survive and thus drive a disease process. Based on this model, we have developed an immunostimulatory therapy that is showing promise inducing both subjective and objective improvement in patients suffering from CFS/ME.

SourceImmunol Res. 2013 Apr 11. [Epub ahead of print]. Proal AD, Albert PJ, Marshall TG, Blaney GP, Lindseth IA. Autoimmunity Research Foundation, 3423 Hill Canyon Ave, Thousand Oaks, CA, 91360, USA.

Post a Comment

Featured Products From the ProHealth Store
B-12 Extreme™ Mitochondria Ignite™ with NT Factor® MitoQ®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments Post a Comment

summary of article
Posted by: Sandy10m
Apr 28, 2013
Here is a general summary of the article. First, these authors believe that CFS and other disease processes are caused by a combination of infections that interplay with each other and your body. This may be why CFS has such a broad range of symptom sets. However, the bottom line is that some CFS patients have VDR (Vitamin D3 receptor) dysregulation. VDR is a 1,25 dihydroxyvitamin D3-activated member of the nuclear receptor superfamily of transcription factors. The diseases manipulate the Vit D3 receptors on cells and interfere with the use of Vit D3. Your blood tests may show a low level of 25-D in your blood (the raw material to make 1,25-D) but a high level of 1,25-D (the immediately usable form). One treatment that they are using in this paper is stimulating the immune system to respond. They use Olmesartan to do this. The patients will usually feel much worse for a long time, but then they slowly start to feel better, and some are cured. If you fall into this category of CFS, you might want to talk to your doctor about this treatment.
Reply Reply
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Subscribe Now!
Receive up-to-date ME/CFS, Fibromyalgia & Lyme Disease treatment and research news
 Privacy Guaranteed  |  View Archives

Repair Damaged Mitochondria and Reduce Fatigue Up to 45%

Featured Products

B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Natural Support for Mood, Sleep and Mental Focus? L-theanine Natural Support for Mood, Sleep and Mental Focus? L-theanine
How Glutathione Can Save Your Life How Glutathione Can Save Your Life
Olea25 Olive Hydroxytyrosol Hits Astonishing 68,000+ ORAC Antioxidant Value Olea25 Olive Hydroxytyrosol Hits Astonishing 68,000+ ORAC Antioxidant Value
IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders
Milk Thistle: Trusted Support for Health & Healing in a Toxic World Milk Thistle: Trusted Support for Health & Healing in a Toxic World

What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Causes
Fibromyalgia Treatments
Fibromyalgia Diet
Fibromyalgia Medications
M.E. & CFS
What is M.E./CFS?
M.E./CFS Diagnosis
M.E./CFS Symptoms
M.E./CFS Causes
M.E./CFS Treatments
M.E./CFS Diet
M.E./CFS Medications
What is Lyme Disease?
Lyme Disease Diagnosis
Lyme Disease Symptoms
Lyme Disease Causes
Lyme Disease Treatments
Lyme Disease Diet
Lyme Disease Medications
M.E. & CFS
Lyme Disease
General Health
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing