Activate Now
ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Abundant Energy Summit: Dr. Myhill speaks about the role of mitochondrial function in ME/CFS

Alcohol intolerance in CFS - gives us a clue as to the mechanisms of fatigue

The "Mind Diet" Reduces the Risk Of Alzheimer’s Dementia. Might It Also Help the Brain Fog Found Wit...

Need Help with Pain Management? There's an App for That

Ask the Doctor: Is CFS an onset to fibromyalgia? What is the difference?

Simplifying Nutritional Support in CFS & Fibromyalgia

How Multiple Chronic Illnesses Shaped One Woman Into a Patient Advocate

Fighting Fatigue with Ground-breaking French Oak Wood Extract

How Walking to Bathroom Can Be Harder Than Running a Marathon: A Doctor’s ME/CFS Case Study

Birds of a Feather: The Joys of Community

Print Page
Email Article

$612,000 Granted to OMI for Critical ME/CFS Research Pilots

  [ 6 votes ]   [ Discuss This Article ] • November 26, 2013

$612,000 Granted to OMI for Critical ME/CFS Research Pilots

Open Medicine Foundation (OMF) is thrilled to announce receipt of $612,000 that will be granted to Open Medicine Institute and its collaborators towards a series of investigative research projects in support of the ME/CFS OMI-MERIT Initiative (see below). These projects will take a deep dive into a small group of patients.

Areas to be studied in this project will include in depth testing on 20 patients:

  • Whole genome sequencing analysis of a cohort of ME/CFS patients – aligned with OMI’s EPE-funded whole genome study (add-on for MERIT #6)

  • A virome survey of oral viral flora (saliva study for MERIT #8).

  • A gene expression study to examine 30,000 human genes for changes in gene expression patterns correlated with improvement/response to treatment (pilots for MERIT #1 and #2).

  • Two proteomic/metabolomic pilot studies (pilot study for MERIT #3 and #7):

  • One looking at over 250,000 protein features per sample. Resulting in a protein profile to compare a baseline ME/CFS patient with responders and non-responders.

  • The second analysis will examine 30,000 smaller molecule profiles representing toxins and metabolites in the same set of samples. This will further our understanding of what a patient’s profile looks like on a molecular level pre and post-treatment.

  • Natural killer cells, B-cells, and T-cells will be looked at for functional performance, activation markers when compared between ill and recovered patients (pilot for MERIT #5 and #9).

  • Other Immunology studies will include single cell measurements, acetylation and other cellular parameters (partial of MERIT #9).

  • Breath testing for GI flora gas production with dietary changes to start looking at the effect of the gut microbiota on the disease, recovery and treatment (1/2 for MERIT #7).

  • Measurement of mitochondrial and related biochemical pathways that play a role in oxidative stress and energy production, adrenal and thyroid pathways that regulate metabolic function along with full panels of pituitary, gonadal, adrenal and other hormones.

  • Brain/Cognitive Data will be collected using unique on-line programs including reaction time, short-term memory, latency, and additional cognitive assessments. These data will be correlated with clinical and molecular endpoints (pilot for MERIT #2).  

  • Quantified-Self (self measurement) projects will rely on wearable devices logging data of activity, heart rate, sleep patterns, blood pressure, heart rate variability (a measure of stress) and others (pilot for MERIT #2).

Leading this research effort will be Andreas Kogelnik, MD, PhD of the OMI.  Kogelnik said, “These  small, in-depth studies involve the laboratories of Ron Davis, PhD (Stanford), Mauro Malnati, PhD (San Raffaele Institute), and a host of international laboratories, companies, clinicians and patients. They leverage our existing global collaborations and help drive the OMI-MERIT initiative forward, performing studies in key areas that will provide a basis for deeper analysis towards understanding ME/CFS.”  

OMF Executive Director, Linda Tannenbaum, announced that funding for these critical projects has come from two anonymous donors that have generously stepped forward to accelerate ME/CFS research to the next level.  In addition, over $12,000 has been received from generous on-line giving from individuals towards the OMI-MERIT Initiative.  She continued that the impact these donors are making provides immeasurable hope for the patient community.   

Please Discuss This Article:   Post a Comment 

[ Be the first to comment on this article ]

Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Subscribe Now!
Receive up-to-date ME/CFS, Fibromyalgia & Lyme Disease treatment and research news
 Privacy Guaranteed  |  View Archives

Vitamins and Supplements for ME/CFS Support

Featured Products

Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth

Natural Remedies

Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep? Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep?
More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History
Aches and Pains? A Simple Solution You'll Love Aches and Pains? A Simple Solution You'll Love
Aching Muscles? Top 10 Nutrients to Take Back Your Life Aching Muscles? Top 10 Nutrients to Take Back Your Life
Fight Inflammation and Promote Cognitive Health with High-OPC Grape Seed Fight Inflammation and Promote Cognitive Health with High-OPC Grape Seed

What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Causes
Fibromyalgia Treatments
Fibromyalgia Diet
Fibromyalgia Medications
M.E. & CFS
What is M.E./CFS?
M.E./CFS Diagnosis
M.E./CFS Symptoms
M.E./CFS Causes
M.E./CFS Treatments
M.E./CFS Diet
M.E./CFS Medications
What is Lyme Disease?
Lyme Disease Diagnosis
Lyme Disease Symptoms
Lyme Disease Causes
Lyme Disease Treatments
Lyme Disease Diet
Lyme Disease Medications
M.E. & CFS
Lyme Disease
General Health
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing