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By Samantha C. Johnston et al.
: Several diagnostic definitions are available for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) that varies significantly in their symptom criteria. This pilot study was conducted to determine whether simple biological and clinical measures differed between CFS/ME patients meeting the 1994 Centres for Disease Control and Prevention (CDC) criteria, the International Consensus Criteria (ICC), as well as healthy controls.
: A total of 45 CFS/ME patients and 30 healthy controls from the South East Queensland region of Australia provided a blood sample, reported on their current symptoms, as well as aspects of their physical and social health using the Short-Form Health Survey (SF-36), and the World Health Organisation Disability Adjustment Schedule 2.0 (WHO DAS 2.0). Differences were examined using independent sample t-testing.
: Patients fulfilling the ICC definition reported significantly lower scores (p?0.05) for physical functioning, physical role, bodily pain, and social functioning than those that only fulfilled the 1994 CDC definition. ICC patients reported significantly greater (p?0.05) disability across all domains of the WHO DAS 2.0.
: These preliminary findings suggest that the ICC identifies a distinct subgroup found within patients complying with the 1994 CDC definition, with more severe impairment to their physical and social functioning.
: Samantha C Johnston, Ekua W Brenu, Sharni L Hardcastle, Teilah K Huth, Donald R Staines and Sonya M Marshall-Gradisnik. Health and Quality of Life Outcomes
2014, 12:64 doi:10.1186/1477-7525-12-64. Published: 30 April 2014