ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|

Trending News

Happiness, Gratitude and Appreciation

New clinical research program to combat chronic pain and chronic fatigue syndrome

It’s Still a Wonderful Life

Lack of Knowledgeable Healthcare Access for Patients with Neuro-endocrine-immune Diseases

Survey Data on Name Change for ME/CFS Analyzed for Publication

Assessment of activity limitations and participation restrictions with persons with chronic fatigue ...

Help the National ME/FM Action Network win $5000!

US Disabled Hold Protests at Bethesda

Shake That *^#&! ing Stigma – The “Shake the CFS Stigma Challenge” Begins

Now Is the Time for a National PR Campaign for ME/CFS!

 
Print Page
Email Article

Important opioid-induced deficiency linked to hot flashes, fatigue, weight gain, depression, more

  [ 72 votes ]   [ 1 Comment ]
www.ProHealth.com • July 29, 2012


Article:
Opioid-Induced Androgen Deficiency (OPIAD)
– Source: Pain Physician, Jul 2012

By Howard S Smith, MD, Jennifer A Elliott, MD

[Note: The free full text of this article is available HERE.]

Abstract:
Opioid therapy is one of the most effective forms of analgesia currently in use. In the past few decades, the use of opioids as a long-term treatment for chronic pain has increased dramatically.

Accompanying this upsurge in the use of long-term opioid therapy has been an increase in the occurrence of opioid associated endocrinopathy, most commonly manifested as an androgen deficiency and therefore referred to as opioid associated androgen deficiency (OPIAD).

This syndrome is characterized by the presence of inappropriately low levels of gonadotropins (follicle stimulating hormone and luteinizing hormone) leading to inadequate production of sex hormones, particularly testosterone.

Symptoms that may manifest in patients with OPIAD include reduced libido, erectile dysfunction, fatigue, hot flashes, and depression.

Physical findings may include:

• Reduced facial and body hair,

• Anemia,

• Decreased muscle mass,

• Weight gain

• And osteopenia or osteoporosis.

Additionally, both men and women with OPIAD may suffer from infertility.

While the literature regarding OPIAD remains limited, it is apparent that OPIAD is becoming increasingly prevalent among chronic opioid consumers but often goes unrecognized.

OPIAD can have a significant negative impact on the quality of life of opioid users, and clinicians should anticipate the potential for its occurrence whenever long-term opioid prescribing is undertaken.

Once diagnosed, treatment for OPIAD may be offered utilizing a number of androgen replacement therapy options including:

• A variety of testosterone preparations,

• And, for female patients with OPIAD, dehydroepiandrosterone (DHEA) supplementation.

Follow-up evaluation of patients receiving androgen replacement therapy should include a review of any unresolved symptoms of hypogonadism, laboratory evaluation, and surveillance for potential adverse effects of androgen replacement therapy including prostate disease in males.

Source: Pain Physician, Jul 2012;15(3 suppl):ES145-56. PMID:22786453, by Smith HS, Elliott JA. Albany Medical College, Albany, NY; University of Missouri-Kansas City School of Medicine, Kansas City, MO. USA. [Email: jelliott@saint-lukes.org]




Please Discuss This Article:   Post a Comment 

Usually higher chances of occurances
Posted by: DanielAndersonABS
Aug 6, 2012
Usually higher chances of occurances in men. We should refrain from consuming painkillers.
Reply Reply
 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Nutritional Supplement Orders

Featured Products

Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History
Protecting Our Eyes Against Time-Induced Damage Protecting Our Eyes Against Time-Induced Damage
The Curcumin Revolution: The Curcumin Revolution: "Golden" Ticket to Better Health
Live Longer: Groundbreaking Research on Omega-3s Live Longer: Groundbreaking Research on Omega-3s
A Breakthrough for Mitochondrial Dysfunction A Breakthrough for Mitochondrial Dysfunction

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing