Activate Now
 
ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

ACTION ALERT: Improve US Chronic Pain Care

Our Mind Wants What Our Body Can't Produce

The Power of Believing You Are Enough

Reversing Alzheimer’s: What Could it Mean for Chronic Fatigue Syndrome (ME/CFS) and Fibromyalgia?

Why Is Chronic Fatigue Syndrome Still a Mystery?

The Blood Volume Paradox in Chronic Fatigue Syndrome (ME/CFS) and POTS

4 Simple Ways to Shift into Positivity

VIDEO: Coping With Chronic Fatigue Syndrome and Fibromyalgia

Big step towards cure for HIV and other lifelong viral infections

Tribunal Orders Release of PACE Data

 
Print Page
Email Article

CFS Patients with POTS: Clinically Distinct Subgroup

  [ 448 votes ]   [ Discuss This Article ]
www.ProHealth.com • December 6, 2012


Article:
Clinical characteristics of a novel subgroup of chronic fatigue syndrome patients with postural orthostatic tachycardia syndrome
– Source: Journal of Internal Medicine, Dec 4, 2012

By I Lewis, J Newton, et al.

[Note: POTS is one of five types of orthostatic intolerance that collectively affect nearly all chronic fatigue syndrome (ME/CFS) patients, according to Dr. David Bell - see “Orthostatic Intolerance and Chronic Fatigue Syndrome.”]

Abstract:
Objectives: A significant proportion of patients with chronic fatigue syndrome (CFS) also have postural orthostatic tachycardia syndrome (POTS). We aimed to characterize these patients and differentiate them from CFS patients without POTS in terms of clinical and autonomic features.

Methods: A total of 179 patients with CFS (1994 Centers for Disease Control and Prevention criteria) attending one of the largest Department of Health-funded CFS clinical services were included in the study.

Outcome measures were:

1. Symptom assessment tools including the fatigue impact scale, Chalder fatigue scale, Epworth sleepiness scale (ESS), orthostatic grading scale (OGS) and hospital anxiety and depression scale (HADS-A and -D, respectively),

2. Autonomic function analysis including heart rate variability and

3. Hemodynamic responses including left ventricular ejection time and systolic blood pressure drop upon standing.

Results:

CFS patients with POTS (13%, n=24) were:

• Younger (29 +/- 12 vs. 42 +/- 13 years, P<0.0001) [probability the difference resulted by chance less than 1 in 10,000],

• Less fatigued (Chalder fatigue scale, 8 +/- 4 vs. 10 +/- 2, P=0.002),

• Less depressed (HADS-D, 6 +/- 4 vs. 9 +/- 4, P=0.01),

• And had reduced daytime hypersomnolence [hypersomnolence is excessive sleeping/sleepiness] (ESS, 7 +/- 6 vs. 10 +/- 5, P=0.02)…

…Compared with patients without POTS.

In addition, they exhibited greater orthostatic intolerance (OGS, 11 +/- 5; P<0.0001) and autonomic dysfunction.

A combined clinical assessment tool of Epworth sleepiness scale 9 or less and orthostatic grading scale 9 or more identifies accurately CFS patients with POTS with 100% positive and negative predictive values.

Conclusions:

The presence of POTS marks a distinct clinical group of CFS patents, with phenotypic features differentiating them from those without POTS.

A combination of validated clinical assessment tools can determine which CFS patients have POTS with a high degree of accuracy, and thus potentially identify those who require further investigation and consideration for therapy to control heart rate.

Source: Journal of Internal Medicine, Dec 4, 2012. PMID:23206180, by Lewis I, Pairman J, Spickett G, Newton JL. Institute for Ageing & Health, Newcastle University, Newcastle, UK. [Email: julia.newton@ncl.ac.uk]





Post a Comment

Featured Products From the ProHealth Store
Hydroxocobalamin Extreme™ Energy NADH™ 12.5mg Ultra ATP+, Double Strength

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 Your Brain Needs for Detox & Sharpness

Natural Remedies

How Glutathione Can Save Your Life How Glutathione Can Save Your Life
Carry a Massage Therapist in Your Pocket Carry a Massage Therapist in Your Pocket
More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History
Restore Youthful Cognition and Well-Being Restore Youthful Cognition and Well-Being
Curcumin - a Golden Gift of Nature with Benefits Still Untold Curcumin - a Golden Gift of Nature with Benefits Still Untold

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map