ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Neuro-inflammation II: The Kynurenine Pathway in Fibromyalgia and ME/CFS

The Neuroinflammation Man: Jarred Younger on Inflammation, Fibromyalgia and Chronic Fatigue Syndrome

Dear Dr. Collins: I’m Disabled. Can the N.I.H. Spare a Few Dimes?

Finding Joy in Every Day

SURVEY RESULTS: What Triggered Your Illness?

7 Things I Have Learned From Having a Chronic Illness

Can Botanicals Beat Brain Fog & Fibrofog?

Rituximab – Promising Effects

Underlying Keys to Recovery and Overcoming Obstacles

CONFERENCE REPORT: Invest in ME 10th Annual Conference, 2015

 
Print Page
Email Article

Acylated ghrelin: A potential marker for fibromyalgia?

  [ 9 votes ]   [ Discuss This Article ]
By D. Homann, et al. • www.ProHealth.com • March 20, 2013


– Source: European Journal of Pain, March 8, 2013

Editor's note:  Acylated ghrelin is the active form of ghrelin, a gastrointestinal hormone which is a strong stimulant of growth hormone from the anterior pituitary. 

Abstract:

BACKGROUND: Fibromyalgia is characterized by chronic widespread pain and sleep disturbances. Overweight and obesity, which lead to metabolic changes, are additional comorbidities that are rarely explored, although they are highly prevalent in patients with fibromyalgia.

METHODS:
We compared the plasma levels of leptin and acylated ghrelin in 17 women with fibromyalgia (patients) and 16 healthy women (controls) with similar age, anthropometric measurements and levels of physical activity. We also investigated the relationships between these two neuropeptides and sleep and various pain characteristics in patients with fibromyalgia. Anthropometric measurements were recorded, and physical activity levels were assessed using a questionnaire. Pain intensity was measured using visual analogue scales (weekly general and mean pain scores). Sleep was assessed using an accelerometry technique.

RESULTS:

  • Compared to the control group, the patient group had increased leptin levels (patients: 22.4?±?10.6 vs. controls: 13.3?±?17.9?ng/mL; p?

  • The leptin level was not significantly correlated with any of the variables.

  • Acylated ghrelin level was inversely correlated with the weekly mean pain score (r?=?-0.67, p?

  • Multiple regression analysis revealed that the variations in acylated ghrelin levels accounted for 35% of the weekly general pain and 29% of the weekly mean pain variability.

CONCLUSIONS: These findings indicate that the decreased acylated ghrelin levels in women with fibromyalgia are related to pain intensity.


Source: European Journal of Pain, March 8, 2013. D. Homann, F.M. Louzada, S.M. Góes, S. Roizenblatt, A.L. Lopes, A.R. de Oliveira, N. Leite. Department of Physical Education, Universidade Federal do Paraná, Curitiba, Brazil.




Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Nutritional Supplement Orders

Featured Products

MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

The Fast-Acting Solution for Healthy Digestive Function The Fast-Acting Solution for Healthy Digestive Function
The Brain Boosting and Fatigue Fighting B-12 The Brain Boosting and Fatigue Fighting B-12
Block food Cravings At Their Molecular Root Block food Cravings At Their Molecular Root
Guarding Against the Dangers of Vitamin D Deficiency Guarding Against the Dangers of Vitamin D Deficiency
Green Coffee Extract: Unique Obesity Intervention Green Coffee Extract: Unique Obesity Intervention

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing