Activate Now
 
ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Ten Tips to Simplify, Lower the Cost, and Optimize CFS and fibromyalgia Treatment

Ampligen Takes Big Step Forward - Becomes First Drug Approved Anywhere For Chronic Fatigue Syndrome

Patient Insights into the Design of Technology to Support a Strengths-Based Approach to Health Care.

Keep Learning – Even From Bed!

Iron Man: A Young Person's POTS ME/CFS Recovery Story Pt. I

Buying Drugs from Canada - A Good Choice for Fibromyalgia and Chronic Fatigue Syndrome (ME/CFS)?

VIDEO: Dear Healthy People: Fatigue

Researchers Identify Characteristic Chemical Signature for Chronic Fatigue Syndrome

SURVEY: Weight Management & Chronic Illness

Researchers find herpes strain in the nervous system

 
Print Page
Email Article

High-Dose Thiamine Improves Fibromyalgia Symptoms

  [ 36 votes ]   [ Discuss This Article ]
www.ProHealth.com • May 31, 2013


High-dose thiamine improves the symptoms of fibromyalgia.

By Antonio Costantini, et al.

Abstract:

Living with fibromyalgia means living with chronic pain, fatigue, sleep disorders and other associated key symptoms. To date, pharmacotherapy generally produces modest benefits.

Some observations indicate that the large majority of symptoms of fibromyalgia could be the clinical manifestation of a mild thiamine deficiency due to a dysfunction of the active transport of thiamine from the blood to the mitochondria or to enzymatic abnormalities.

Between June and July 2011, we recruited three female patients affected by fibromyalgia. We proceeded with the study of the patients' history, a physical examination, an evaluation of chronic widespread pain using the Visual Numeric Scale and an evaluation of the fatigue using the Fatigue Severity Scale were also performed. The levels of thiamine and thiamine pyrophosphate in the blood were determined.

After the therapy with high doses of thiamine, in the patients, there was an appreciable improvement of the symptoms.

Source: BMJ Case Reports, May 20, 2013. By Antonio Costantini, Maria Immacolata Pala, Silvia Tundo, and Pietro Matteucci. Department of Neurological Rehabilitation of the Clinic, Villa Immacolata, Viterbo, Italy.

Editor's comment:  Although this was a very small study and there was not a healthy control group for comparison, the results are nevertheless noteworthy. 

  • Patient 1:  71.3% reduction in fatigue; 80% reduction in pain.

  • Patient 2:  37% reduction in fatigue; 50% reduction in pain.

  • Patient 3:  60.7% reduction in fatigue; 60% reduction in pain.

The therapeutic doses of thiamine ranged from 600 mg to 1800 mg per day.  One patient reported improvement at 600 mg.  The doses for the other two patients were increased by 300 mg. every three days.  Neither reported any improvement until they reached a dosage of 1500 mg.  The final therapeutic dose for both was 1800 mg.  None of the patients in this study experienced any side effects.  The authors did note, however, that in some studies using high-dose thiamine for other illnesses, a few patients experienced side effects like tachycardia and insomnia.  Additional and larger studies are needed to confirm these results.





Post a Comment

Featured Products From the ProHealth Store
B-12 Extreme™ Mitochondria Ignite™ with NT Factor® Energy NADH™ 12.5mg

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Herbal Rescue for High Blood Sugar Herbal Rescue for High Blood Sugar
SAM-e: a Hard-Working Molecule that May Help Ease Pain & Brighten Mood SAM-e: a Hard-Working Molecule that May Help Ease Pain & Brighten Mood
Health Benefits Are Brewing in Green Tea Health Benefits Are Brewing in Green Tea
Energy Breakthrough - One Fibromyalgia Patient’s Fortuitous Discovery Energy Breakthrough - One Fibromyalgia Patient’s Fortuitous Discovery
How Glutathione Can Save Your Life How Glutathione Can Save Your Life

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map