Activate Now
ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Alcohol intolerance in CFS - gives us a clue as to the mechanisms of fatigue

The "Mind Diet" Reduces the Risk Of Alzheimer’s Dementia. Might It Also Help the Brain Fog Found Wit...

Simplifying Nutritional Support in CFS & Fibromyalgia

Need Help with Pain Management? There's an App for That

How Walking to Bathroom Can Be Harder Than Running a Marathon: A Doctor’s ME/CFS Case Study

Ask the Doctor: Is CFS an onset to fibromyalgia? What is the difference?

How Multiple Chronic Illnesses Shaped One Woman Into a Patient Advocate

Fighting Fatigue with Ground-breaking French Oak Wood Extract

Is Your Body Your Friend and Healing Ally?

Birds of a Feather: The Joys of Community

Print Page
Email Article

Different ME/CFS symptoms linked to activity of HHV-6/HHV-7 vs parvovirus B19: Clue to subsets?

  [ 10 votes ]   [ Discuss This Article ] • August 30, 2012

Association of Active Human Herpesvirus-6, -7 and Parvovirus B19 Infection with Clinical Outcomes in Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
-  Source: Advances in Virology, Aug 13, 2012

By Svetlana Chapenko, et al.

[Note: The full text of this article can be found at]

Frequency of active human herpesvirus-6, -7 (HHV-6, HHV-7) and parvovirus B19 (B19) infection/coinfection and its association with clinical course of ME/CFS was evaluated.

108 ME/CFS patients and 90 practically healthy persons were enrolled in the study.

Viral genomic sequences were detected by PCR, virus-specific antibodies and cytokine levels - by ELISA, HHV-6 variants - by restriction analysis.

Active viral infection including concurrent infection was found in 64.8% (70/108) of patients and in 13.3% (12/90) of practically healthy persons.

Increase in peripheral blood leukocyte DNA HHV-6 load as well as in proinflammatory cytokines' levels was detected in patients during active viral infection.

• Definite relationship was observed between:

- Active beta-herpesvirus [HHV-6 and HHV-7] infection and subfebrility [temp slightly above normal], lymphadenopathy [lymph node swelling] and malaise after exertion,

- And between active B19 infection and multi-joint pain.

• Neuropsychological disturbances were detected in all patients.

• The manifestation of symptoms was of more frequent occurrence in patients with concurrent infection.

The high rate of active HHV-6, HHV-7 and B19 infection / coinfection with the simultaneous increase in plasma proinflammatory cytokines' level as well as the association between active viral infection and distinctive types of clinical symptoms shows necessity of simultaneous study of these viral infections for identification of possible subsets of ME/CFS.

Source: Advances in Virology, Aug 13, 2012. doi:10.1155/2012/205085, by Chapenko S, Krumina A, Logina I, Rasa S, Chirstjakovs M, Sultanova A, Viksna L, Murovska M. August Kirchenstein Institute of Microbiology and Virology & Departments of Infectology and Dermatology and Neurology and Neurosurgery, Riga Stradins University, Riga, Latvia.

Please Discuss This Article:   Post a Comment 

[ Be the first to comment on this article ]

Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Subscribe Now!
Receive up-to-date ME/CFS, Fibromyalgia & Lyme Disease treatment and research news
 Privacy Guaranteed  |  View Archives

Vitamins and Supplements for ME/CFS Support

Featured Products

Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Coenzyme Q10 - The Energy Maker Coenzyme Q10 - The Energy Maker
Prepare Yourself for Cold & Flu Season
Sleep Like a Baby in Nature's Cradle Sleep Like a Baby in Nature's Cradle
Herbal Inflammation Management for Whole Body Health Herbal Inflammation Management for Whole Body Health
Are You Obtaining the Proper Enzymes? Are You Obtaining the Proper Enzymes?

What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Causes
Fibromyalgia Treatments
Fibromyalgia Diet
Fibromyalgia Medications
M.E. & CFS
What is M.E./CFS?
M.E./CFS Diagnosis
M.E./CFS Symptoms
M.E./CFS Causes
M.E./CFS Treatments
M.E./CFS Diet
M.E./CFS Medications
What is Lyme Disease?
Lyme Disease Diagnosis
Lyme Disease Symptoms
Lyme Disease Causes
Lyme Disease Treatments
Lyme Disease Diet
Lyme Disease Medications
M.E. & CFS
Lyme Disease
General Health
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing