ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Beginning Again: Living with the Ups and Downs of Life with Chronic Illness

Chronic Christmas: Surviving the Holidays with a Chronic Illness

SURVEY RESULTS: Cognitive Impairment II

Productivity Values That Get in the Way of Our Health

Happiness, Gratitude and Appreciation

10 Questions to Ask Yourself Before Saying Yes

The “Starvation” Disease? Metabolomics Meets Chronic Fatigue Syndrome Down Under

Vital Molecule Increases Cellular Energy and Improves Cognitive Function

The IACFS/ME 2016 Conference Overviews #1: Energy and Exercise To the Fore

Is Chronic Fatigue Syndrome An Inflammatory Disease? The 2016 IACFS/ME Conference Overviews Pt II

 
Print Page
Email Article

Is Chronic Fatigue Syndrome in Older Patients a different disease? – a clinical cohort study

  [ 9 votes ]   [ 2 Comments ]
www.ProHealth.com • February 13, 2013


Is Chronic Fatigue Syndrome in Older Patients a different disease? – a clinical cohort study

  –Source: Eur J Clin Invest, 2012

Abstract

Background: Chronic fatigue syndrome (CFS) is a disabling disorder characterised by persistent fatigue with a typical age of diagnosis of 35–50 years. CFS does present in those aged over 50 but whether this is a different disease in older age groups has not been considered. Therefore, we performed a clinical cohort study to examine and differentiate the clinical and autonomic features in CFS patients aged over 50.

Design: A total of 179 Fukuda diagnosed CFS patients were recruited, and 25 older CFS patients (50 + years) were matched case by case for gender and length of history to 25 younger CFS patients (16–29 years). A range of symptomatic-based questionnaires were used in addition to heart rate variability and baroreceptor sensitivity to assess autonomic function.

Results: Chronic fatigue syndrome can present for the first time in an older population. Older CFS patients demonstrate increased fatigue (Fatigue impact scale; 85 ± 33 vs. 107 ± 27, P = 0·02) (Chalder fatigue scale; 9 ± 3 vs. 11 ± 1, P = 0·002) and caseness for depression (Hospital Anxiety and Depression scale; 7 ± 3 vs. 10 ± 4; P = 0·005). There is a greater autonomic dysfunction in older CFS patients, with reduced parasympathetic function (HFnu; 49·1 ± 18 vs. 36·2 ± 18, P = 0·01, RR30 : 15; ± , P = 0·02) and increased sympathetic function (LFnu; 51·5 ± 17 vs. 63·8 ± 18, P = 0·01). Baroreflex sensitivity was substantially reduced (BRS; 19·7 ± 12 vs. 9·9 ± 5, P = 0·0004), and left ventricular ejection time prolonged (LVET; 274·6 ± 16 vs. 285·8 ± 9, P = 0·004).

Conclusions: Older CFS patients demonstrate a disease phenotype very different from younger patients. The combination of differing underlying pathogenic mechanisms and the physiological aspects of ageing result in a greater disease impact in older CFS patients.

Source: Eur J Clin Invest, 2012. Article first published online: 9 Feb 2013 [doi: 10.1111/eci.12046]. Ieuan Lewis, Institute for Ageing & Health, Newcastle University, Newcastle upon Tyne, UK; Jessie Pairman, Newcastle Hospitals NHS Foundation Trust, Northern CFS Clinical Network, Newcastle upon Tyne, UK; Gavin Spickett, Newcastle Hospitals NHS Foundation Trust, Northern CFS Clinical Network, Newcastle upon Tyne, UK; Julia L. Newton, Institute for Ageing & Health, Newcastle University, Newcastle upon Tyne, UK, Newcastle Hospitals NHS Foundation Trust, Northern CFS Clinical Network, Newcastle upon Tyne, UK NIHR Biomedical Research Centre in Ageing, Newcastle University, Newcastle upon Tyne, UK.





Post a Comment

Featured Products From the ProHealth Store
Hydroxocobalamin Extreme™ Ultra ATP+, Double Strength Mitochondria Ignite™ with NT Factor®


Article Comments Post a Comment

Is this about CFS another name for ME or about psychiatry messing around
Posted by: simmons1
Feb 14, 2013
not to long ago back in the dark ages of my ME childhood children were claimed not to get ME instead school phobia was given as a reason for why children were believing themselves sick or Munchhausen by proxy were the mother was accused of creating ME in the minds of their children by psychiatrists . Now that i am getting older my ME is going to be put down to psychological problems due to old age a totally separate ME from my younger ME version of myself can i trust this research ,is it about old age or ME or is it just another psychological fix up job another spin to make ME the non disease lumped in with some sort of old age psychological theory to damage ME.
Reply Reply

I may have got this wrong
Posted by: simmons1
Feb 15, 2013
I may have jumped to conclusion here as I may have mistaken physiological aspects of aging as psychological aspects of aging I have also discovered that Gavin Spickett works in Immunology in Newcastle and this is an area that has an important part to play in researching ME .I apologize for being Hasty and harsh in my comment here it is very hard to determine what is going on in ME and should have checked my facts it is important that science looks into this illness .
Reply Reply
 
Natural Pain Relief Supplements

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 Your Brain Needs for Detox & Sharpness
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria

Natural Remedies

Probiotic Mint Promotes Healthy Gums & Teeth, Freshens Breath and Whitens Teeth Probiotic Mint Promotes Healthy Gums & Teeth, Freshens Breath and Whitens Teeth
Fight Inflammation and Promote Cognitive Health with High-OPC Grape Seed Fight Inflammation and Promote Cognitive Health with High-OPC Grape Seed
Physically and Mentally Exhausted? How to Restore Energy at Its Source Physically and Mentally Exhausted? How to Restore Energy at Its Source
The Brain Boosting and Fatigue Fighting B-12 The Brain Boosting and Fatigue Fighting B-12
When a Negative is Positive - Goodnighties Recovery Sleepwear When a Negative is Positive - Goodnighties Recovery Sleepwear

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map