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Pycnogenol® Supplementation Improves Health Risk Factors in Subjects with Metabolic Syndrome.

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By G. Belcaro et al • • February 19, 2013

~Source: Phytother Res. January 28, 2013.

By G. Belcaro G et al. 


This open, controlled study evaluated the effects of 6?month supplementation with Pycnogenol® maritime pine bark extract on health risk factors in subjects with metabolic syndrome. Pycnogenol® was used with the aim of improving risk factors associated with metabolic syndrome, central obesity, elevated triglycerides (TG), low HDL cholesterol, high blood pressure and fasting blood glucose.

Sixty-four subjects (range 45-55?years) presenting with all five risk factors of metabolic syndrome were included, and Pycnogenol® was administered for 6?months. A group of 66 equivalent subjects were followed up as controls. In the 6-month study Pycnogenol® supplementation 150?mg/day decreased waist circumference, TG levels, blood pressure and increased the HDL cholesterol levels in subjects.

Pycnogenol lowered fasting glucose from baseline 123?±?8.6?mg/dl to 106.4?±?5.3 after 3?months and to 105.3?±?2.5 at the end of the study (p?

Source:  Phytother Res. 2013 Jan 28. doi: 10.1002/ptr.4883. [Epub ahead of print]. Belcaro G, Cornelli U, Luzzi R, Cesarone MR, Dugall M, Feragalli B, Errichi S, Ippolito E, Grossi MG, Hosoi M, Cornelli M, Gizzi G. Irvine3 Labs, Department Biomedical Sciences, CH-PE University.

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