ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|

Trending News

Gut Infection Could Underlie Symptoms in Chronic Fatigue Syndrome

NIH Pathways to Prevention: Advancing the Research on ME/CFS: Day 1, Afternoon Sessions

The Biggest Chronic Fatigue Syndrome Treatment Trial Begins: Fluge/Mella On Rituximab

Chronic Fatigue Syndrome Researcher Turns Pilot Study into Major Grant

NIH Pathways to Prevention: Advancing the Research on ME/CFS: Day 1, Morning Session

Fatigue & Fibro Fog: Could You Have a B-12 Deficiency?

Plasma cytokine expression in adolescent chronic fatigue syndrome

Ask the Doctor: How do I know that I really have chronic fatigue syndrome?

Paradoxical response to intravenous immunoglobulin in a case of Parvovirus B19-associated chronic fa...

Effect of high dose vitamin C on Epstein-Barr viral infection

 
Print Page
Email Article

Anti-inflammatory Compound Helps Woman With CFS Return to Work

  [ 3 votes ]   [ 2 Comments ]
www.ProHealth.com • March 16, 2013


Editor's Note:  Alpha-1 antitrypsin (AAT) protects tissues from enzymes of inflammatory cells, especially neutrophil elastase. It is excreted by neutrophils and macrophages during inflammation, and destroys both bacteria and host tissue.

Alpha-1 antitrypsin and chronic fatigue syndrome: a case study from pathophysiology to clinical practice

~Source: Pain Management, March 2013

By José Alegre at el.

SUMMARY 

Background: Several lines of evidence support the involvement of inflammatory and immunologic abnormalities in chronic fatigue syndrome (CFS). Since recent studies have shown that alpha-1 antitrypsin (AAT) possesses anti-inflammatory properties, the potential therapeutic effect of AAT treatment on CFS has been investigated. 

Case presentation: A 49-year-old woman diagnosed with CFS was treated with intravenous infusions of a human plasma-derived AAT concentrate (60 mg/kg body weight weekly for 8 consecutive weeks). The patient’s monocyte elastase, a regulator of inflammatory processes, was 1170 U/mg. At completion of treatment, improvement in maximal workload was observed (54.0–71.7% of predicted). Additionally, amelioration in working memory (scores: 83–94) and perceptual organization (scores: 75–83) were detected on the Wechsler Adult Intelligence Scale-III test. Monocyte elastase decreased to a normal range (<150 U/mg). Improvement in functional capacity allowed the patient to work in part-time employment. 

Conclusion: These findings suggest a possible role for AAT in the treatment of CFS.

Source: Pain Management, March 2013, Vol. 3, No. 2, Pages 119-122 , DOI 10.2217/pmt.12.84. José Alegre, Chronic Fatigue Syndrome Unit, Hospital Vall d'Hebron, Passeig Vall Hebron 119-129, 08035 Barcelona, Spain; Sandra Camprubí, Clinical Trials & Pharmacovigilance Department, Instituto Grifols S.A. Can Guasch 2, 08150 Parets del Vallès, Barcelona, Spain; and Ana García-Quintana, Chronic Fatigue Syndrome Unit, Centro Médico Delfos, Avinguda de Vallcarca 151, 08023 Barcelona, Spain.




Please Discuss This Article:   Post a Comment 

One woman
Posted by: roge
Mar 16, 2013
is this some kind of joke - one woman - cmon

Dont even bother telling me if something works unless you have at least 100 patients and double blinded - please
Reply Reply

 
cfs
Posted by: roge
Mar 16, 2013
ok i may have been a bit harsh above as at least conclusion says may play a possible role - but still

 

 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Repair Damaged Mitochondria and Reduce Fatigue Up to 45% Repair Damaged Mitochondria and Reduce Fatigue Up to 45%
Protect Against Sun-Induced Skin Aging From The Inside Out Protect Against Sun-Induced Skin Aging From The Inside Out
The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol
Could a B-12 Deficiency Be Causing Your Symptoms? Could a B-12 Deficiency Be Causing Your Symptoms?
IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing