Activate Now
 
ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

How to Cope When Others Don't Understand Your Illness

There and Back Again – a CFS/Fibromyalgia Physician’s Recovery

Call to Action: Funding for ME/CFS Stricken From 2016 Federal Budget!

OMF's Severely Ill Patient Study Gets Large Donation

5 Health Strategies You Can Learn from Your Dog

Re-evaluating Your Habits

Increased Risk of Chronic Fatigue Syndrome Following Atopy: A Population-Based Study

Weeding Out Your Negative Thoughts!

Clinically Studied Joint Relief Product for FM & ME/CFS

Restoring Cellular Energy Metabolism

 
Print Page
Email Article

Anti-inflammatory Compound Helps Woman With CFS Return to Work

  [ 3 votes ]   [ 2 Comments ]
www.ProHealth.com • March 16, 2013


Editor's Note:  Alpha-1 antitrypsin (AAT) protects tissues from enzymes of inflammatory cells, especially neutrophil elastase. It is excreted by neutrophils and macrophages during inflammation, and destroys both bacteria and host tissue.

Alpha-1 antitrypsin and chronic fatigue syndrome: a case study from pathophysiology to clinical practice

~Source: Pain Management, March 2013

By José Alegre at el.

SUMMARY 

Background: Several lines of evidence support the involvement of inflammatory and immunologic abnormalities in chronic fatigue syndrome (CFS). Since recent studies have shown that alpha-1 antitrypsin (AAT) possesses anti-inflammatory properties, the potential therapeutic effect of AAT treatment on CFS has been investigated. 

Case presentation: A 49-year-old woman diagnosed with CFS was treated with intravenous infusions of a human plasma-derived AAT concentrate (60 mg/kg body weight weekly for 8 consecutive weeks). The patient’s monocyte elastase, a regulator of inflammatory processes, was 1170 U/mg. At completion of treatment, improvement in maximal workload was observed (54.0–71.7% of predicted). Additionally, amelioration in working memory (scores: 83–94) and perceptual organization (scores: 75–83) were detected on the Wechsler Adult Intelligence Scale-III test. Monocyte elastase decreased to a normal range (<150 U/mg). Improvement in functional capacity allowed the patient to work in part-time employment. 

Conclusion: These findings suggest a possible role for AAT in the treatment of CFS.

Source: Pain Management, March 2013, Vol. 3, No. 2, Pages 119-122 , DOI 10.2217/pmt.12.84. José Alegre, Chronic Fatigue Syndrome Unit, Hospital Vall d'Hebron, Passeig Vall Hebron 119-129, 08035 Barcelona, Spain; Sandra Camprubí, Clinical Trials & Pharmacovigilance Department, Instituto Grifols S.A. Can Guasch 2, 08150 Parets del Vallès, Barcelona, Spain; and Ana García-Quintana, Chronic Fatigue Syndrome Unit, Centro Médico Delfos, Avinguda de Vallcarca 151, 08023 Barcelona, Spain.




Please Discuss This Article:   Post a Comment 

One woman
Posted by: roge
Mar 16, 2013
is this some kind of joke - one woman - cmon

Dont even bother telling me if something works unless you have at least 100 patients and double blinded - please
Reply Reply

 
cfs
Posted by: roge
Mar 16, 2013
ok i may have been a bit harsh above as at least conclusion says may play a possible role - but still

 

 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Nutritional Supplement Orders

Featured Products

Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders
Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue
Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask
Red Yeast Rice - Natural Option for Supporting Healthy Cholesterol Red Yeast Rice - Natural Option for Supporting Healthy Cholesterol
Quercetin: Natural Support for Allergy & Inflammation Relief and More Quercetin: Natural Support for Allergy & Inflammation Relief and More

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing