ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|

Trending News

Powerful Evidence That Chronic Fatigue Syndrome (CFS) And Fibromyalgia (FM) Are Real And Mainly Phys...

Study shows why exercise magnifies exhaustion for chronic fatigue syndrome patients

The Importance of Forgiveness When Living with Chronic Illness

5 Tips for Successfully Changing Your Diet

Fatigue & Fibro Fog: Could You Have a B-12 Deficiency?

A Commercially Available Probiotic Reduces Chronic Fatigue Syndrome’s Inflammation—Should we offer t...

Evidence in chronic fatigue syndrome for severity-dependent upregulation of prefrontal myelination t...

The experience of sleep in chronic fatigue syndrome: A qualitative interview study with patients

Call to Action: Congressional Hearing on Ampligen

Cytokines in the Cerebrospinal Fluids of Patients with Chronic Fatigue Syndrome/Myalgic Encephalomye...

 
Print Page
Email Article

Altered Distribution of Lymphocyte Populations in Chronic Fatigue Syndrome Patients

  [ 9 votes ]   [ Discuss This Article ]
By Isabel Barao et al. • www.ProHealth.com • June 30, 2014


By Isabel Barao, Ph.D., Daniel Peterson, M.D., Dorothy Hudig, Ph.D

Abstract

Objective: The goal of our research is to define immunologic deficiencies of patients with chronic fatigue syndrome (CFS) and ultimately to improve the health of these patients by increasing their immunity.

Setting: CFS is a debilitating disease of unknown cause(s) defined by the Centers for Disease Control and Prevention (CDC) in Atlanta, GA. Our patient population is the well-known Reno-Lake Tahoe CFS cohort.

Methods: Peripheral blood is the site of traffic of lymphocytes with varying roles in immunity. Lymphocytes are circulating so as to be available to fight infections anywhere in the body or trafficking into secondary lymphoid organs where the lymphocytes will proliferate and differentiate. There are different types of lymphocytes in the blood [including helper T cells, cytotoxic T cells, T cells, B cells, natural killer (NK), and NK-T cells]. Alterations in these populations from healthy individuals are a hallmark of immune stress. To profile these populations, we used flow cytometry with fluorescent antibodies to identify the different populations of lymphocytes in the peripheral blood of CFS patients.

Results: We found unusual increases in a 'hybrid' population of lymphocytes in CFS patients. This population has features of both T cells and NK cells and is normally 1-5% of all lymphocytes but can be as high as 30% in the CFS patients.

Interpretation: The results are consistent with altered immunity in CFS patients, particularly altered immune responses to chronic viral infections. Further characterization, including repeated tests of the same patients, is needed to determine if this unusual population is persistent and to determine if it can mediate cytotoxicity towards virally infected cells.

Source: Mountain West Clinical Translational Research. 2014.Presentation.



Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Itching to Find Dry Skin Relief? Itching to Find Dry Skin Relief?
Optimize Your Immune System Naturally: Thymic Protein A Optimize Your Immune System Naturally: Thymic Protein A
Quercetin: Natural Support for Allergy & Inflammation Relief and More Quercetin: Natural Support for Allergy & Inflammation Relief and More
Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance
The 10 Supplements Dr. Teitelbaum Recommends Most Often for Those with Top Health Issues The 10 Supplements Dr. Teitelbaum Recommends Most Often for Those with Top Health Issues

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing