Two sinus surgeries caused no improvement, much pain, great expense. Most Rx's and Rx spays, nothing. Do learn to recognize and avoid all chemicals that trigger MCS: perfumes, cleaning chemicals, smoke, gasoline and hydrocarbon fumes etc. Do study migraine and allergy diets. First, avoid all ferments: alcohol, vinegar, yeast foods, even soy sauce. If you are very allergic or immune compromised, you may have to give up common allergens, wheat, dairy, eggs. See details of the Swank Diet for MS. These measures have definitely worked in my case. Try Nasonex over other Rx sprays, it is water based. Why avoid gas fumes, and then spray alcohol and formaldehyde up your nose? Use sinus irrigations, you'll get used to it, and welcome it when it begins to offer relief. Try Imitrex, it works. After 40 years of migraine, I was hard to convince that anything would. Essential oil combination of thyme, cinnamon, and clove is a very strong decongestant. I paid double the price of the oils for this secret formula online, yours free. Last but not least, the best natural decongestant spray AND headache relief I have found in 50 years, Sinus Buster hot pepper spray! The Pharmaceutical industry announced this as the greatest coming thing since shredded wheat, 10 years ago, then dropped it because they couldn't get an exclusive patent to monopolize a natural molecule and its profits. Everyone is different, but these are some of the only things that have helped me at all in 50 years, and I spent a great deal of time, money, brainpower, effort, and suffering to find them. Good luck with these and your own research.