{"title":"Build Your NMN Stack","description":"","products":[{"product_id":"prohealth-nadh-coq10-60-vegetarian-capsules-ph513","title":"NADH + CoQ10 - 60 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003ch2\u003eCrucial coenzymes for energy, stamina, cellular health and cognitive function.\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eHelps support ATP production for increased energy levels\u003c\/li\u003e\n\u003cli\u003eSupports greater mental focus and memory\u003c\/li\u003e\n\u003cli\u003eCoQ10 acts as an antioxidant to fight oxidative stress in cells\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH513_-_Beacon_Point_COA_LOT_2509136_2025-10-20.pdf?v=1761156343\" rel=\"noopener noreferrer\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eResearch-Supported Benefits:\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Energy Levels.\u003c\/strong\u003e Each molecule of NADH produces three molecules of energy in the form of ATP, giving your body a boost in a non-stimulating way. Both NADH and CoQ10 are essential coenzymes for making energy from food. Research shows that people who took 20 mg of NADH with 200 mg of coenzyme Q10 for eight weeks had significantly reduced fatigue and increased ATP production.\u003csup\u003e1\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Cellular Health.\u003c\/strong\u003e Oxidative damage is a cause of accelerated aging and the development of age-related disorders CoQ10 is an important antioxidant that fights oxidative stress that damages our cells.\u003csup\u003e2\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Cognitive Function.\u003c\/strong\u003e NADH has been studied for its role in supporting brain health and mental clarity. A 6-month clinical study showed that people who took 10 mg of NADH per day exhibited significantly higher scores of memory performance, including verbal fluency and reasoning.\u003csup\u003e3\u003c\/sup\u003e In animals, CoQ10 supplementation improves learning and memory deficits.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Castro-Marrero J, Cordero MD, Segundo MJ, et al. Does oral coenzyme Q10 plus NADH supplementation improve fatigue and biochemical parameters in chronic fatigue? Antioxid Redox Signal. 2015;22(8):679-685.\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4346380\/\" style=\"color: #0000ff;\" target=\"_blank\"\u003edoi:10.1089\/ars.2014.6181 \u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e2. Saini R. Coenzyme Q10: The essential nutrient. J Pharm Bioallied Sci. 2011;3(3):466-467. doi:10.4103\/0975-7406.84471 \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3178961\/\" style=\"color: #0000ff;\" target=\"_blank\"\u003edoi:10.4103\/0975-7406.84471 \u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e3. Demarin V, Podobnik SS, Storga-Tomic D, Kay G. Treatment of [AD] with stabilized oral nicotinamide adenine dinucleotide: a randomized, double-blind study. Drugs Exp Clin Res. 2004;30(1):27-33. PMID: \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15134388\/\" style=\"color: #0000ff;\" target=\"_blank\"\u003e15134388 \u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e4. Monsef A, Shahidi S, Komaki A. Influence of Chronic Coenzyme Q10 Supplementation on Cognitive Function, Learning, and Memory in Middle-Aged Rats. Neuropsychobiology. 2019;77(2):92-100. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30580330\/\" style=\"color: #0000ff;\" target=\"_blank\"\u003edoi:10.1159\/000495520 \u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-how-it-work-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003eEvery cell in the body requires ATP (energy) to function properly and a continual supply of this crucial element is essential to the proper function of the heart, brain, nerves and muscles. NADH and CoQ10 are crucial coenzymes for producing cellular energy. Adding daily supplementation of NADH and CoQ10 can help to support ATP production, providing increased energy levels, improved mood and greater mental focus.\u003c\/li\u003e\n\u003cli\u003eNADH helps with energy levels because each molecule of NADH produces three molecules of energy in the form of ATP.\u003c\/li\u003e\n\u003cli\u003eCoQ10 also helps with energy levels because it is an essential coenzyme needed to make energy from food.\u003c\/li\u003e\n\u003cli\u003eThe form of CoQ10 in this formula is Ubiquinone.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable style=\"height: 123.433px;\" width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 20.5333px;\"\u003e\n\u003cth colspan=\"3\" style=\"font-size: 11pt; font-weight: bold; height: 20.5333px;\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd style=\"height: 17.15px;\" colspan=\"3\" class=\"smalltext\"\u003eServing Size: 1 Capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd style=\"height: 17.15px;\" colspan=\"3\" class=\"smalltext\"\u003eServings Per Container: 60\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd colspan=\"2\" style=\"font-weight: bold; height: 17.15px;\" class=\"smalltext\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 17.15px;\" class=\"smalltext\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd style=\"height: 17.15px;\" class=\"smalltext\"\u003eCoQ10 (Coenzyme Q10 as Ubiquinone)\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 17.15px;\" class=\"smalltext\" align=\"right\"\u003e100 mg\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 17.15px;\" class=\"smalltext\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd style=\"height: 17.15px;\" class=\"smalltext\"\u003eNADH (Reduced β-Nicotinamide Adenine Dinucleotide Disodium Salt)\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 17.15px;\" class=\"smalltext\" align=\"right\"\u003e25 mg\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 17.15px;\" class=\"smalltext\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd style=\"height: 17.15px;\" colspan=\"3\" class=\"smalltext\"\u003e† Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV.08.25\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS:\u003c\/strong\u003e\u003cspan\u003e R\u003c\/span\u003eice bran. hypromellose (capsule), microcrystalline cellulose.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e Take one (1) capsule per day, without food, preferably in the morning.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN.\u003c\/strong\u003e Store in a cool and dry place aer opening.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"summary-copy\"\u003e\n\u003cp\u003e\u003cstrong\u003ePatented.\u003c\/strong\u003e Compared to other products, ProHealth's NADH + CoQ10 uses a patented delayed-release capsule (DRcaps) to protect the delicate co-enzymes from stomach acid and release their content in the small intestines for better absorption.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTaste and Odor-Masking Properies. \u003c\/strong\u003e Additionally, it has taste and odor-masking properties to decrease stomach discomfort.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQuality-Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"ProHealth Longevity","offers":[{"title":"Default Title","offer_id":24226587672676,"sku":"PH513","price":39.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH513_175ML_FRNT-600x600-REV0825.png?v=1778162862"},{"product_id":"prohealth-hydroxytyrosol-extreme-90-capsules-ph398","title":"Hydroxytyrosol Extreme™ - 25 mg, 90 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003ch2\u003eProtects cardiovascular tissue from free radical damage and supports a healthy inflammatory response.\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports heart and heart function \u003c\/li\u003e\n\u003cli\u003eStrengthens the body's immune system \u003c\/li\u003e\n\u003cli\u003eSlows down the aging process \u003c\/li\u003e\n\u003cli\u003eSupports various organ health \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca style=\"color: #0000ff;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH398-_COA_Qalitex_LOT_2508125_2025-10-09.pdf?v=1761145708\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eResearch-Supported Benefits:\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eProtects Cardiac and Endothelial Tissue.\u003c\/strong\u003e Human studies have shown that hydroxytyrosol supplementation decreases inflammatory markers. It also increases production of superoxide dismutase (SOD), the body’s own antioxidant, to reduce tissue damage.\u003csup\u003e1\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePromotes Healthy Blood Markers:\u003c\/strong\u003e Hydroxytyrosol metabolites attach to excess lipids in the blood and remove them, leading to a decrease in blood lipids. This reduction can reduce the immune response which is a key factor in aging-related damage to blood vessels.\u003csup\u003e1\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDecreases Free-Radical Burden:\u003c\/strong\u003e Hydroxytyrosol reduces excess free-radicals and nitric oxide, which are signaling molecules that can lead to DNA and protein damage. Additionally, it can activate certain anti-inflammatory proteins which can help improve tissue health in the blood vessels, digestive system,and liver.\u003csup\u003e1\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports DNA Health:\u003c\/strong\u003e Activates expression of the sirtuins through the same mechanisms as caloric restriction. In addition, hydroxytyrosol encourages the destruction of abnormal cells without inhibiting the function of healthy cells.\u003csup\u003e2\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Boss A, Bishop KS, Marlow G, Barnett MPG, Ferguson LR. Evidence to support the anti-cancer effect of olive leaf extract and future directions. Nutrients. 2016;8(8):513. doi:10.3390\/nu8080513 \u003cbr\u003e\u003cbr\u003e2. Sharifi-Rad J, Rodrigues CF, Sharopov F, et al. Diet, lifestyle and cardiovascular diseases: linking pathophysiology to cardioprotective effects of natural bioactive compounds. International Journal of Environmental Research and Public Health. 2020;17(7):2326. doi:10.3390\/ijerph17072326 doi:10.3390\/ijerph17072326\u003cbr\u003e\u003cbr\u003e3. Lockyer S, Yaqoob P, Spencer JPE, Rowland I. Olive leaf phenolics and cardiovascular risk reduction: Physiological effects and mechanisms of action. Nutrition and Aging. 2012;1(2):125-140. doi:10.3233\/NUA-2012-0011\u003cbr\u003e\u003cbr\u003e4. Vijakumaran U, Shanmugam J, Heng JW, et al. Effects of hydroxytyrosol in endothelial functioning: a comprehensive review. Molecules. 2023;28(4):1861. doi:10.3390\/molecules28041861\u003cbr\u003e\u003cbr\u003e5. Robles-Almazan M, Pulido-Moran M, Moreno-Fernandez J, et al. Hydroxytyrosol: Bioavailability, toxicity, and clinical applications. Food Research International. 2018;105:654-667. doi:10.1016\/j.foodres.2017.11.053 \u003cbr\u003e\u003cbr\u003e6. Robles-Almazan M, Pulido-Moran M, Moreno-Fernandez J, et al. Hydroxytyrosol: Bioavailability, toxicity, and clinical applications. Food Research International. 2018;105:654-667. doi:10.1016\/j.foodres.2017.11.053\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-how-it-work-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003eHydroxytyrosol is present in small amounts in olive oil and is thought to be one of the reasons those who eat a Mediterranean style diet experience slower aging and better health into older age.\u003csup\u003e2\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eHydroxytyrosol, a primary bioactive agent found in olive leaves and olive oil, has the greatest measured antioxidant capacity of all tested polyphenols with an ORAC score of 68,576. This small molecule is able to cross the blood-brain barrier and diffuse through tissues to capture free radicals and nitric oxygen species.\u003csup\u003e1\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eHydroxytyrosol reduces inflammation in tissues and decreases the response of the immune system.\u003csup\u003e4\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eHydroxytyrosol Extreme™ is rapidly absorbed through the intestines and into circulation to deliver antioxidant and anti-inflammatory effects throughout tissues in the cardiovascular system, digestive tissue, and the liver. It facilitates more effective absorption of vitamins A, D, and K. \u003c\/li\u003e\n\u003cli\u003eHydroxytyrosol slows the aging of tissues by reducing free radical damage and enhancing transcription of sirtuins.\u003csup\u003e1\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable border=\"0\" cellpadding=\"0\" cellspacing=\"2\" style=\"width: 100%;\" data-mce-style=\"width: 100%;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth align=\"left\" style=\"font-size: 11pt; font-weight: bold;\" colspan=\"3\" data-mce-style=\"font-size: 11pt; font-weight: bold;\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003eServing Size: 1 Capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003eServings Per Container: 90\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" style=\"font-weight: bold;\" colspan=\"2\" data-mce-style=\"font-weight: bold;\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap;\" data-mce-style=\"white-space: nowrap;\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eOlive Leaf Extract 25% Hydroxytyrosol (\u003cem\u003eOlea25™\u003c\/em\u003e) Yielding 25 mg Hydroxytyrosol\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap;\" data-mce-style=\"white-space: nowrap;\"\u003e100 mg\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap;\" data-mce-style=\"white-space: nowrap;\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003e†Daily Value not established.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nRev. 10.23 \n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eRice flour, vegetable capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDOES NOT CONTAIN:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eDairy, egg, soy, wheat, gluten, corn, fish, shellfish, tree nuts, peanuts.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e Take 1 capsule daily, or as recommended by your healthcare professional.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNOTE:\u003c\/strong\u003e Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e People sensitive or allergic to olives or olive leaf should not take this product. Not intended for use by pregnant or nursing women. Not formulated for use in children. If you have a medical condition or are taking medications,\u003cbr data-mce-fragment=\"1\"\u003econsult with your healthcare professional before using this product.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"summary-copy\"\u003e\n\u003cp\u003e\u003cstrong\u003eBetter Absorption.\u003c\/strong\u003e Olea25™ proprietary extraction process yields a hydroxytyrosol concentration standardized to an unprecedented 25%, compared to other products that commonly standardize their hydroxytyrosol supplements to 6% or less. This combination helps to slow the absorption allowing it to work longer in the body.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResearch-Supported.\u003c\/strong\u003e Hydroxytyrosol has been extensively studied for its cardiovascular and anti-inflammatory benefits. Hydroxytyrosol Extreme™ is formulated to have the highest potency available standardized to 25%, compared to others which are standardized to 6% or less, to promote longevity and decrease age-related loss of function through improved heart function, normal immune response, and healthy levels of inflammation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"ProHealth Longevity","offers":[{"title":"Default Title","offer_id":24332743278692,"sku":"PH398","price":36.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH398_175ML_FRNT_600x600_6a316130-34c5-4e3e-9ed8-57761d5a4e5c.png?v=1737588816"},{"product_id":"prohealth-trans-resveratrol-1000-mg-60-capsules-ph528","title":"Trans-Resveratrol Plus - 1000 mg per serving, 60 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eRevitalize Aging Cells with the World's Most Researched Trans-Resveratrol*\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eClear out \"zombie\" senescent cells*\u003csup\u003e1\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eActivate the SIRT1 \"longevity gene\"*\u003csup\u003e2,3,4\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eIncrease nutrient and oxygen delivery to cells*\u003csup\u003e5\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eWhat Makes Our Trans Resveratrol Better?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMost Researched:\u003c\/strong\u003e 13 published human clinical studies - more than any other Trans-Resveratrol. No guesswork - just results.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuperior Source:\u003c\/strong\u003e Most resveratrol comes from Japanese Knotweed, which is banned in countries like Japan because of impurities and toxins. We use a better source for unmatched purity, safety and reliability.  \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSwiss Precision Processing:\u003c\/strong\u003e Our Trans-Resveratrol is created by a Swiss biotech company using their patented fermentation process for a pure, potent, and pharmaceutical-quality product. \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDoctor-Formulated Potency:\u003c\/strong\u003e Featuring a 1,000mg \"longevity dose\" of Trans-Resveratrol, plus full-spectrum polyphenols and bio-enhancers to maximize absorption and bioavailability.* \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHighest Purity:\u003c\/strong\u003e Industry-leading 98% purity. \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTriple Lab Tested:\u003c\/strong\u003e Tested three times by independent 3rd-party labs to ensure they meet the highest standards.  \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eComplete Transparency:\u003c\/strong\u003e In an industry flooded with fake supplements, we stand apart by publishing our 3rd-party lab test results. We're committed to showing you exactly what's in every bottle, so you can feel confident in what you're putting into your body.  \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUSA Manufacturing Excellence:\u003c\/strong\u003e Made in FDA-regulated, GMP-certified facilities in the USA for the highest quality and safety.  \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e100-Day Risk-Free Guarantee:\u003c\/strong\u003e We stand behind our products. Not satisfied? Reach out to our Santa Barbara, CA office for a full refund within 100 days – no hassle, no questions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eThe Ingredient That Started The Movement\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eResveratrol was the revolutionary ingredient that ignited the entire longevity movement. After a landmark 2003 study revealed it as a powerful activator of sirtuins, and subsequent studies showed its ability to extend lifespan (by 10% in roundworms and fruit flies, and 25% in mice), it quickly captured global attention and sparked an explosion of research into its potential for human health and longevity.*\u003csup\u003e‡6,7,8\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eBuilding on this groundbreaking discovery, ProHealth's Trans-Resveratrol emerged as the world's most clinically studied form of resveratrol, validated by 13 human trials that demonstrate its powerful effects on critical aspects of aging, including brain and heart health, skin vitality, and other age-related changes. ProHealth’s Trans-Resveratrol stands as the pinnacle of resveratrol innovation, delivering unparalleled potency and scientifically backed results to help you age with vitality and strength.*\u003csup\u003e9\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eRevitalize Your Aging Cells*\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eClear Out \"Zombie\" Senescent Cells*\u003c\/strong\u003e \u003cbr\u003eMake room for healthier, more vibrant cells to thrive. By combining Trans-Resveratrol and Quercetin, our formula acts as a powerful \u003cstrong\u003esenolytic\u003c\/strong\u003e, disrupting the Senescent Cell Anti-Apoptotic Pathways (SCAPs) that allow damaged senescent cells to linger inside the body.*\u003csup\u003e1\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eActivate the SIRT1 \"Longevity Gene\"*\u003c\/strong\u003e\u003cbr\u003eTrans-Resveratrol switches on the \u003cstrong\u003eSIRT1 \"longevity gene\"\u003c\/strong\u003e - boosting your cells' ability to repair, function, and thrive like they did when you were younger.*\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eThe Secret Behind the French Paradox: SIRT1*\u003c\/strong\u003e\u003cbr\u003eDespite a diet rich in fats, the French have robust cardiovascular health - thanks in part to resveratrol-rich red wine. Each dose of Trans-Resveratrol Plus 1000 delivers the concentrated resveratrol content and SIRT1-boosting power equivalent to 550 bottles of red wine.*\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e Mimics the Benefits of Fasting: SIRT1*\u003c\/strong\u003e\u003cbr\u003eFasting and calorie restriction are known to activate SIRT1. Trans-Resveratrol acts as a powerful \"fasting mimetic,\" boosting SIRT1 activity without the need for caloric reduction.*\u003csup\u003e2,3,4\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eIncrease Nutrient and Oxygen Delivery*  \u003cbr\u003e\u003c\/strong\u003eTrans-Resveratrol widens blood vessels by 23%, promoting healthy blood flow to ensure your cells receive vital nutrients and oxygen while efficiently removing waste for optimal cellular function.*\u003csup\u003e10\u003c\/sup\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBoost Nitric Oxide Production*\u003c\/strong\u003e\u003cbr\u003eTrans-Resveratrol Plus 1000 activates \u003cstrong\u003eendothelial nitric oxide synthase\u003c\/strong\u003e (eNOS), helping to maintain healthy nitric oxide levels. Nitric oxide works to relax and widen blood vessels, promoting blood flow throughout your body.*\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupport Multiple Tissues at Once*\u003c\/strong\u003e\u003cbr\u003eNearly every tissue in your body thrives with increased access to nutrients and oxygen. This is how Trans-Resveratrol supports everything from skin, bone, and eye health, to cardiovascular and cognitive function.*\u003csup\u003e11\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eFeel the Difference with ProHealth Trans-Resveratrol Plus 1000\u003c\/strong\u003e\u003cbr\u003eExperience the purest, most researched, and most effective Trans-Resveratrol supplement available. Don't just slow the signs of aging—revitalize your health at the cellular level with ProHealth Trans-Resveratrol Plus 1000.*\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOrder now and join the 200,000+ people who trust ProHealth 1000mg Trans Resveratrol Plus for their cellular health!  \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eIngredient Info\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eResveratrol:\u003c\/strong\u003e A polyphenol antioxidant commonly found in red grapes. We utilize the biologically active \"trans\" form of resveratrol, produced through an innovative yeast fermentation process that delivers a high-purity finished product (\u0026gt;98% trans-resveratrol).\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRed Wine Extract:\u003c\/strong\u003e A concentrated powder packed with grape-derived nutrients—such as resveratrol, quercetin, tannins, catechins, and polyphenols—delivering the benefits of red wine without the alcohol content.*\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuercetin:\u003c\/strong\u003e A naturally occurring yellow plant pigment and one of the most abundant bioflavonoids in foods, commonly supplemented as quercetin dihydrate to enhance stability.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGreen Tea Extract:\u003c\/strong\u003e A powerful tea leaf extract standardized for EGCG, the key active compound known for its antioxidant and health-promoting properties.*\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBioPerine\u003csup\u003e®\u003c\/sup\u003e: \u003c\/strong\u003eA concentrated black pepper extract standardized to 95% piperine, clinically studied to boost absorption and bioavailability.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e\u003csup\u003e‡\u003c\/sup\u003e\u003c\/b\u003eThese results have not been replicated in humans.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003csup\u003e1\u003c\/sup\u003eKohandel Z et al. Curr Mol Med. 2024;24(7),867-875.\u003cbr\u003e\u003csup\u003e2\u003c\/sup\u003eKuršvietienė L et al. Medicina. 2016;52(3),148-155.\u003cbr\u003e\u003csup\u003e3\u003c\/sup\u003eLakshminarasimhan M et al. Aging (Albany NY). 2013;5(3),151. \u003cbr\u003e\u003csup\u003e4\u003c\/sup\u003eBorra MT et al. J Biol Chem. 2005;280(17),17187-17195.\u003cbr\u003e\u003csup\u003e5\u003c\/sup\u003eXia N et al. Molecules. 2014;19(10),16102-16121.\u003cbr\u003e\u003csup\u003e6\u003c\/sup\u003eHowitz KT et al. Nature. 2003;425(6954),191-196.\u003cbr\u003e\u003csup\u003e7\u003c\/sup\u003eWood JG et al. Nature. 2004;430(7000),686-689. \u003cbr\u003e\u003csup\u003e8\u003c\/sup\u003eBaur JA et al. Nature. 2006;444(7117),337-342. \u003cbr\u003e\u003csup\u003e9\u003c\/sup\u003eZaw JJ et al. Menopause. 2021;28(1),40-49. \u003cbr\u003e\u003csup\u003e10\u003c\/sup\u003eWong RHX et a. J Hypertens. 2013;31,1819–1827. \u003cbr\u003e\u003csup\u003e11\u003c\/sup\u003eXia N et al. Molecules. 2014;19(1),16102-16121.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable border=\"0\" cellpadding=\"0\" cellspacing=\"2\" width=\"100%\" style=\"height: 174.883px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 20.5333px;\"\u003e\n\u003cth align=\"left\" colspan=\"3\" style=\"font-size: 11pt; font-weight: bold; height: 20.5333px;\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 17.15px;\"\u003eServing Size: 2 Capsules\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 17.15px;\"\u003eServings Per Container: 30\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd colspan=\"2\" class=\"smalltext\" style=\"font-weight: bold; height: 17.15px;\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap; height: 17.15px;\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 17.15px;\"\u003ePure  Veri-te® Trans-Resveratrol\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap; height: 17.15px;\"\u003e1000 mg\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap; height: 17.15px;\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 68.6px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 68.6px;\"\u003eProprietary Blend\u003cbr\u003eQuercetin Dihydrate (from \u003cem\u003eSophora japonica\u003c\/em\u003e Flower Extract), Red Wine (\u003cem\u003eVitis vinifera\u003c\/em\u003e) Fruit Extract, Green Tea Leaf Extract, BioPerine® Black Pepper Fruit Extract (95% Piperine)®\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap; height: 68.6px;\"\u003e420 mg\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap; height: 68.6px;\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 17.15px;\"\u003e† Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV.08.25\u003cbr\u003eVeri-te® is a registered trademark of the Lallemand group. BioPerine® is a registered trademark of Sabinsa, Co.\u003cbr\u003e\u003cbr\u003e** Herbal products such as this are likely to have minor color variation from batch to batch because of the geographical and seasonal variations of the raw material.\u003cbr\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eHypromellose (capsule), rice flour.\u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE: \u003c\/strong\u003eTake two (2) capsules per day, with food, preferably in the morning.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION: \u003c\/strong\u003eFor use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. KEEP OUT OF REACH OF CHILDREN. Store in a cool and dry place after opening.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNOTE:\u003c\/strong\u003e Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN.\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Longevity","offers":[{"title":"Default Title","offer_id":31385226477668,"sku":"PH528","price":31.08,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH528_175CC_FRNT_600x600-REV0825.png?v=1770653127"},{"product_id":"prohealth-bulk-trans-resveratrol-pure-powder-100-grams-ph571","title":"Trans-Resveratrol Pure Powder - 100 grams","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003ch2\u003eSupports brain, cardiovascular, cellular and joint health\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports brain health and cognitive function\u003c\/li\u003e\n\u003cli\u003eSupports cellular and DNA health\u003c\/li\u003e\n\u003cli\u003eSupports healthy aging\u003c\/li\u003e\n\u003cli\u003eSupports heart and metabolic health\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH571_-_COA_Brighton_LOT_25579_2025.09.30_2.pdf?v=1759935232\" rel=\"noopener noreferrer\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eResearch-Supported Benefits:\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Brain Health\u003c\/strong\u003e. Research shows that resveratrol, a molecule found in red grapes and wine, may protect the brain from symptoms of brain aging, including improving memory and delaying cognitive decline. The neuroprotective effects of resveratrol come from its sirtuin-activating, inflammation-regulating, mitochondrial-supporting and antioxidant activity. (1-3)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Cellular and DNA Health\u003c\/strong\u003e. Resveratrol acts as a potent antioxidant, which reduces harmful oxidative stress. It also activates genes called sirtuins. Healthy sirtuin activity helps to fight cellular senescence, support DNA repair, boost mitochondrial function and generate cellular energy through ATP production. (3,4)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Healthy Aging\u003c\/strong\u003e. Resveratrol activates SIRT1, often referred to as the \"longevity gene.\" Healthy older adults tend to have higher levels of SIRT1 activity, and SIRT1 overexpression can increase lifespan in worms and animals. In humans, SIRT1 supports healthy aging and longevity. (5,6)\u003c\/p\u003e\n\u003cp\u003eSupports Joint Health. Due to its role in supporting healthier inflammatory responses and modulating oxidative stress, resveratrol has exhibited joint-protective effects. (7)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Heart Health\u003c\/strong\u003e. Resveratrol is well-known for its link to supporting cardiovascular health. Research has found that resveratrol benefits endothelial function, blood vessel health and blood pressure by boosting SIRT1 activity, reducing oxidative stress and increasing nitric oxide production. (8,9)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Metabolic Health\u003c\/strong\u003e. Resveratrol activates SIRT1, which has been studied for its role in supporting healthier glucose metabolism. People with reduced SIRT1 expression tend to have higher blood sugar, poor glucose control and metabolic disorders. (10)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Salehi B, Mishra AP, Nigam M, et al. Resveratrol: A Double-Edged Sword in Health Benefits. Biomedicines. 2018;6(3):91. Published 2018 Sep 9. \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6164842\/\" target=\"_blank\"\u003edoi:10.3390\/biomedicines6030091\u003c\/a\u003e \u003cbr\u003e\u003cbr\u003e2. Bastianetto S, Ménard C, Quirion R. Neuroprotective action of resveratrol. Biochim Biophys Acta. 2015;1852(6):1195-1201. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25281824\/\"\u003edoi:10.1016\/j.bbadis.2014.09.011\u003c\/a\u003e \u003cbr\u003e\u003cbr\u003e3. Moraes DS, Moreira DC, Andrade JMO, Santos SHS. Sirtuins, brain and cognition: A review of resveratrol effects. IBRO Rep. 2020;9:46-51. Published 2020 Jun 26. \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7733131\/?report=reader\"\u003edoi:10.1016\/j.ibror.2020.06.004\u003c\/a\u003e\u003cspan class=\"TextRun SCXW41998961 BCX2\" style=\"font-size: 11pt; line-height: 21.85px; font-family: Calibri, 'Calibri_EmbeddedFont', 'Calibri_MSFontService', sans-serif;\" data-contrast=\"auto\" lang=\"EN\"\u003e\u003cspan class=\"NormalTextRun SCXW41998961 BCX2\"\u003e\u003c\/span\u003e\u003c\/span\u003e \u003cbr\u003e\u003cbr\u003e4. Borra MT, Smith BC, Denu JM. Mechanism of human SIRT1 activation by resveratrol. J Biol Chem. 2005;280(17):17187-17195. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15749705\/\"\u003edoi:10.1074\/jbc.M501250200 \u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e5. Kilic U, Gok O, Erenberk U, et al. A remarkable age-related increase in SIRT1 protein expression against oxidative stress in elderly: SIRT1 gene variants and longevity in human. PLoS One. 2015;10(3):e0117954. Published 2015 Mar 18. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15749705\/\"\u003edoi:10.1371\/journal.pone.0117954\u003c\/a\u003e \u003cbr\u003e\u003cbr\u003e6. Salminen A, Kaarniranta K. SIRT1: regulation of longevity via autophagy. Cell Signal. 2009;21(9):1356-1360. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19249351\/\"\u003edoi:10.1016\/j.cellsig.2009.02.014 \u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e7. Nguyen C, Savouret JF, Widerak M, Corvol MT, Rannou F. Resveratrol, Potential Therapeutic Interest in Joint Disorders: A Critical Narrative Review. Nutrients. 2017;9(1):45. Published 2017 Jan 6. \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5295089\/?report=classic\"\u003edoi:10.3390\/nu9010045\u003c\/a\u003e \u003cbr\u003e\u003cbr\u003e8. Marques BCAA, Trindade M, Aquino JCF, et al. Beneficial effects of acute trans-resveratrol supplementation in treated hypertensive patients with endothelial dysfunction. Clin Exp Hypertens. 2018;40(3):218-223. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29431520\/\"\u003edoi:10.1080\/10641963.2017.128874\u003c\/a\u003e1 \u003cbr\u003e\u003cbr\u003e9. Bonnefont-Rousselot D. Resveratrol and Cardiovascular Diseases. Nutrients. 2016;8(5):250. Published 2016 May 2. \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4882663\/\"\u003edoi:10.3390\/nu8050250\u003c\/a\u003e \u003cbr\u003e\u003cbr\u003e10. Hou CY, Tain YL, Yu HR, Huang LT. The Effects of Resveratrol in the Treatment of Metabolic Syndrome. Int J Mol Sci. 2019;20(3):535. Published 2019 Jan 28. \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6387422\/\"\u003edoi:10.3390\/ijms20030535 \u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"summary-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBest Form of Resveratrol.\u003c\/strong\u003e Other resveratrol supplements are typically composed of 50% trans-resveratrol and 50% cis-resveratrol. ProHealth uses trans-resveratrol because it has a higher biological availability.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuperior Absorption.\u003c\/strong\u003e The particles provide superior absorption and the 100 gram container is perfect for people wanting to buy in bulk.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNatural Source.\u003c\/strong\u003e ProHealth’s trans-resveratrol is pure and natural for the highest quality.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigher Dose.\u003c\/strong\u003e Each serving contains 1000 mg pure and natural trans-resveratrol.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdditional Certifications.\u003c\/strong\u003e Non-GMO, Vegan and Gluten-Free\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth colspan=\"3\" style=\"font-size: 11pt; font-weight: bold;\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003eServing Size: 1 Scoop\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003eServings Per Container: 100\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"2\" class=\"smalltext\" style=\"font-weight: bold;\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eVeri-te® Trans-Resveratrol\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e1000 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003e† Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV. 09.25\u003cbr\u003eVeri-te® is a registered trademark of the Lallemand group.\u003cbr\u003e\u003cbr\u003e** Herbal products such as this are likely to have minor color variation from batch to batch because of the geographical and seasonal variations of the raw material.\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS:\u003c\/strong\u003e None.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e Add one (1) scoop to 8-12 oz of liquid per day, mix thoroughly and drink.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN.\u003c\/strong\u003e Store in a cool and dry place after opening.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is sold by weight, not volume. Contents may settle during shipping and handling. Each leveled scoop contains approximately 1,000 mg. A milligram scale is recommended for an exact dose.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-how-it-work-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003eResveratrol is a naturally occurring polyphenol that works by activating longevity genes called sirtuins, acting as an antioxidant, regulating inflammatory responses and supporting mitochondrial health.\u003c\/li\u003e\n\u003cli\u003eTrans-resveratrol is the most bioavailable form of resveratrol.\u003c\/li\u003e\n\u003cli\u003eProHealth's Pure Trans-Resveratrol powder delivers 1000 mg of pharmaceutical grade, 98% pure, natural trans-resveratrol per serving.\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Longevity","offers":[{"title":"Default Title","offer_id":33039826485348,"sku":"PH571","price":84.75,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH571_FRNT_6.5x10.5_Bag-600x600_REV0925.png?v=1780607073"},{"product_id":"prohealth-tmg-pro-tablets-1000-mg-120-tablets-ph568","title":"TMG Pro Tablets - 1000 mg, 120 tablets","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003ch2\u003eA methyl donor that complements NMN and supports heart health and liver detoxification.\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports liver detoxification \u003c\/li\u003e\n\u003cli\u003eSupports cardiovascular health \u003c\/li\u003e\n\u003cli\u003ePromotes healthy homocysteine levels \u003c\/li\u003e\n\u003cli\u003eSupports cellular health \u003c\/li\u003e\n\u003c\/ul\u003e\n  \u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH568-_TAL_LOT_2409101_2025-01-15.pdf?v=1741987566\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"color: #0000ff;\"\u003eView Certificate of Analysis  \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eResearch-Supported Benefits:\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Cellular Health.\u003c\/strong\u003e TMG is an amino acid that supports the body's methylation processes. Methylation is essential for numerous important cellular functions, including cell division, energy production and producing antioxidants to fight oxidative stress.\u003csup\u003e1\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Detoxification.\u003c\/strong\u003e The donation of methyl groups by TMG is critical for healthy liver function and detoxification.\u003csup\u003e1\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Cardiovascular Health.\u003c\/strong\u003e TMG may decrease blood levels of homocysteine, an amino acid that is linked to poor heart health and blood vessel damage when elevated.\u003csup\u003e2\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Arumugam MK, Paal MC, Donohue TM Jr, Ganesan M, Osna NA, Kharbanda KK. Beneficial Effects of Betaine: A Comprehensive Review. Biology (Basel). 2021;10(6):456. Published 2021 May 22. doi:10.3390\/biology10060456 \u003cbr\u003e\u003cbr\u003e2. McRae MP. Betaine supplementation decreases plasma homocysteine in healthy adult participants: a meta-analysis. J Chiropr Med. 2013;12(1):20-25. doi:10.1016\/j.jcm.2012.11.001 doi:10.1016\/j.jcm.2012.11.001 \u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-how-it-work-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003eTrimethylglycine (TMG), also known as betaine anhydrous, is an amino acid that supports the body's methylation processes. \u003c\/li\u003e\n\u003cli\u003eMethylation is a fundamental biochemical process in which one carbon atom and three hydrogen atoms (CH3) are transferred from one molecule to another. \u003c\/li\u003e\n\u003cli\u003eMethylation is responsible for numerous important bodily functions, such as cell division, cellular energy production, clearing histamine, metabolism, DNA expression (epigenetics), forming neurotransmitters and producing free radical-scavenging antioxidants. \u003c\/li\u003e\n\u003cli\u003eOur bodies contain a “methyl pool” of CH3 that is available whenever needed. As long as we have enough methyl groups stored in the pool, methylation typically is not a problem. However, there are a couple of things that may contribute to the depletion of the body's methyl pool. \u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMTHFR Variants\u003c\/strong\u003e - Methylenetetrahydrofolate reductase (MTHFR) is a gene with common mutations that can interfere with the methylation process, causing high levels of homocysteine (a known risk factor in heart health conditions) in the blood and low folate levels. Up to 40% of the population may have one or both genetic mutations. \u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAging and Epigenetics\u003c\/strong\u003e - Methylation of DNA plays a crucial role in epigenetics, switching different sequences of your genetic material on and off as needed. The body's methylation ability and subsequent DNA expression are known to decline with age. Anti-aging researchers think these changes in DNA expression may be a contributing factor to many age-related diseases. \u003c\/li\u003e\n\u003cli\u003eNMN Supplementation and Methylation Support. When taken as a supplement, NMN may require the use of methyl groups to help facilitate the conversion of NAD+ in your cells, thereby activating sirtuin genes and promoting longevity. Although there is currently no evidence suggesting NMN’s natural methylation process depletes the methyl pool, many top anti-aging experts suggest that safeguarding against methyl depletion may be a wise proactive step to augment your NMN intake. \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth style=\"font-size: 11pt; font-weight: bold;\" colspan=\"3\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003eServing Size: 1 Tablet\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003eServings Per Container: 120\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold;\" class=\"smalltext\" colspan=\"2\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eTrimethylglycine (TMG) (Betaine Anhydrous)\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e1 g (1000 mg)\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003e† Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV.10.23\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eCellulose, stearic acid (vegetable source), croscarmellose sodium, magnesium stearate (vegetable source).\u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDOES NOT CONTAIN: \u003c\/strong\u003eDairy, egg, soy, wheat, gluten, corn, fish, shellfish, tree nuts, peanuts.\u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE: \u003c\/strong\u003eTake 1-6 tablets daily, divided into 2 doses, or as recommended by your healthcare professional.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e Not intended for use by pregnant or nursing women. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your healthcare professional before using this product.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNOTE:\u003c\/strong\u003e Keep the bottle tightly closed at all times in between usage. Keep the freshness packet in bottle. This product is very sensitive to moisture\/humidity which may affect product stability. Store in a cool dry place after opening. KEEP OUT OF REACH OF CHILDREN\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\u003cdiv class=\"summary-copy\"\u003e\n\u003cp\u003e\u003cstrong\u003eTablet Form.\u003c\/strong\u003e The tablet form of TMG Pro makes it easy to take.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHigher Dose.\u003c\/strong\u003e ProHealth’s TMG Pro contains 1,000 mg of TMG as Betaine Anhydrous, whereas other TMG supplements may contain just 750 mg.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFree of Unwanted Ingredients.\u003c\/strong\u003e TMG Pro doesn’t contain yeast, wheat, gluten, sugar, salt, dairy, eggs, peanuts, tree nuts, fish, shellfish, soy, corn, dye or preservatives.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in USA laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"ProHealth Longevity","offers":[{"title":"Default Title","offer_id":39264685424740,"sku":"PH568","price":16.57,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH568_400ML_FRNT_600x600_13bdc64c-2a7d-420e-83a1-11837d2afbe6.png?v=1737676750"},{"product_id":"prohealth-longevity-fisetin-pro-longevity-60-capsules-ph590","title":"Fisetin Pro Longevity Plus - 60 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003ch2\u003eSupport and Maintain Healthy Brain Function\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports longevity\u003c\/li\u003e\n\u003cli\u003ePromotes brain health\u003c\/li\u003e\n\u003cli\u003eEnhances cellular health\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca style=\"color: #0000ff;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH590_-_COA_Brighton_LOT_26038_2025-12-01-1_2.pdf?v=1765471220\" target=\"_blank\"\u003eView Certificate of Analysis »\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eResearch-Supported Benefits:\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Longevity\u003c\/strong\u003e. Fisetin supports longevity by aiding in the removal of senescent cells from the body. (1) Senescent cells, also known as zombie cells, accumulate as we age and contribute to oxidative stress, inflammation and accelerated cellular aging. Research shows that removing senescent cells extends lifespan in animals. (1)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePromotes Brain Health\u003c\/strong\u003e. Research shows that fisetin supplementation may reduce symptoms of age-related brain health decline. (2) Functioning as an antioxidant to reduce neuroinflammation, fisetin has been shown to enhance learning and memory. (2) Additionally, fisetin may prevent brain cell death associated with brain aging. (2)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEnhances Cellular Health\u003c\/strong\u003e. Oxidative stress contributes to cellular damage and accelerated cellular aging. While inflammation and oxidative stress are natural, high levels of oxidative stress and inflammation dramatically reduce longevity. Research shows that fisetin supplementation may reduce oxidative stress and inflammation due to its antioxidant effects, thus promoting longevity. (3)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Yousefzadeh MJ, Zhu Y, McGowan SJ, et al. Fisetin is a senotherapeutic that extends health and lifespan. EBioMedicine. 2018;36:18-28. doi:10.1016\/j.ebiom.2018.09.015 \u003cbr\u003e\u003cbr\u003e 2. Nabavi SF, Braidy N, Habtemariam S, Sureda A, Manayi A, Nabavi SM. Neuroprotective Effects of Fisetin in Alzheimer's and Parkinson's Diseases: From Chemistry to Medicine. Curr Top Med Chem. 2016;16(17):1910-1915. doi:10.2174\/1568026616666160204121725 \u003cbr\u003e\u003cbr\u003e 3. Jiang K, Yang J, Xue G, Dai A, Wu H. Fisetin Ameliorates the Inflammation and Oxidative Stress in Lipopolysaccharide-Induced Endometritis. J Inflamm Res. 2021;14:2963-2978. Published 2021 Jul 5. doi:10.2147\/JIR.S314130\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth colspan=\"3\" style=\"font-size: 11pt; font-weight: bold;\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003eServing Size: 1 Capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003eServings Per Container: 60\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"2\" class=\"smalltext\" style=\"font-weight: bold;\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003e\n\u003cstrong\u003eProprietary Lifespan Absorption Blend™\u003c\/strong\u003e \u003cbr\u003eGlucomannan, Marshmallow (root), Green Tea extract (leaf) standardized to 95% EGCG, Long Pepper extract 4:1 (fruit), Quercetin, Turmeric extract (root) standardized to 95% curcuminoids \u003cbr\u003e\n\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e350 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eFisetin\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e125 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eMCT Oil Powder\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e25 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003e† Daily Value not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nRev. 12.23\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS:\u003c\/strong\u003e Vegetable capsule, brown rice flour. \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDOES NOT CONTAIN:\u003c\/strong\u003e Dairy, egg, soy, wheat, gluten, corn, fish, shellfish, tree nuts, peanuts. \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e Take 1 or 2 capsules daily, or as recommended by your healthcare professional. \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSTORAGE:\u003c\/strong\u003e Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN.\u003c\/strong\u003e \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e Not intended for use if you are pregnant or nursing. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your healthcare professional before using this product. Do not take turmeric if you have a biliary tract obstruction or are taking a steroidal anti-inflammatory such as prednisone.\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-how-it-work-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003eFisetin is one of the most potent senolytic compounds in existence. Senolytics are defined as nutrients that aid in the removal of senescent cells from the body. As senescent cells accumulate, oxidative stress and longevity decrease.\u003c\/li\u003e\n\u003cli\u003eDNA damage accelerates cellular aging. Fisetin may protect against DNA damage and promote DNA repair.\u003c\/li\u003e\n\u003cli\u003eFisetin exhibits powerful antioxidant effects, reducing oxidative stress and inflammation.\u003c\/li\u003e\n\u003cli\u003eAs we age, our brain cells degrade due to oxidative stress—the buildup of inflammatory compounds called reactive oxygen species. As an antioxidant, fisetin fights off oxidative stress that damages our cells, including neurons. Fisetin also has exhibited beneficial effects on age-related changes in the brain by triggering signaling pathways that promote brain cell growth and neuronal integrity.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"summary-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnique Formulation.\u003c\/strong\u003e The majority of fisetin products have poor absorption. To help, we added a Proprietary Lifespan Absorption Blend™ to dramatically enhance bioavailability and efficacy and support various aspects of health.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIncreased Absorption.\u003c\/strong\u003e To further enhance absorption, we included MCT Oil Powder. Adding a fat to the product helps increases the body’s ability to utilize fisetin.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupported for Daily Use.\u003c\/strong\u003e Compared to other fisetin products that are intended to be used 1-2 times per week, our formula is safe enough to be used daily.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Longevity","offers":[{"title":"Default Title","offer_id":39380391559268,"sku":"PH590","price":37.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH590_FRNT_250ML_600x600_4426467d-1bd4-4678-89c0-bda2810f5af5.png?v=1738081048"},{"product_id":"prohealth-longevity-berberine-pro-600-mg-60-capsules-ph613","title":"Berberine Pro - 600 mg, 60 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eDiscover the Power of Berberine—Advanced Metabolic Support for Healthy Aging.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHelps maintain healthy blood sugar levels*\u003csup\u003e1-6\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eSupports cardiovascular health and lipid metabolism*\u003csup\u003e1-6\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eSupports a balanced gut microbiome*\u003csup\u003e3,5,7\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eActivates AMPK, the \"longevity switch\" of cellular energy and metabolism* \u003csup\u003e1-2\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH613_-_Qalitex_COA_LOT_2510149_2025-11-14.pdf?v=1764198055\" rel=\"noopener noreferrer\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eBerberine is a powerful metabolic optimizer that enhances the body’s ability to process carbohydrates and fats. It promotes the conversion of food into energy, supports nutrient storage and distribution, and aids systems that manage energy balance. By optimizing these key metabolic processes, berberine helps the body utilize nutrients more effectively.*\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eWhat Makes Ours Better?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eUltra-Pure Extract:\u003c\/strong\u003e Sourced from the bark of Indian barberry (Berberis aristata), ensuring both exceptional purity and potency, backed by centuries of traditional use.* \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinical Strength:\u003c\/strong\u003e Each capsule delivers a precise 600mg dose, optimized for maximum efficacy.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTargeted Support:\u003c\/strong\u003e Formulated with alpha-lipoic acid (ALA) to enhance antioxidant protection and support cellular energy.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnhanced Absorption:\u003c\/strong\u003e Features BioPerine® black pepper extract to boost nutrient absorption and bioavailability.*\u003csup\u003e8\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eWhy Choose ProHealth?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDoctor-Formulated:\u003c\/strong\u003e Developed by our in-house science team in collaboration with leading wellness experts to address the root causes of aging.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTriple Lab Tested:\u003c\/strong\u003e Rigorously tested three times by independent third-party labs to guarantee unmatched potency and purity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFull Transparency:\u003c\/strong\u003e In an industry full of misleading claims, we publish our third-party lab results—so you always know exactly what’s in every bottle.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eManufactured in the USA:\u003c\/strong\u003e Since 1988, we’ve proudly produced our supplements in FDA-regulated, GMP-certified facilities, ensuring the highest quality and safety standards.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e100-Day Risk-Free Guarantee:\u003c\/strong\u003e We stand behind our products. If you’re not completely satisfied, contact our Santa Barbara, CA office for a full refund—no hassle, no questions asked.*\u003csup\u003e8\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eAdvanced Metabolic Support for Healthy Aging\u003cbr\u003e\u003c\/strong\u003eBerberine is a bioactive plant extract with a rich history of use in Ayurvedic and Chinese medicine. As a “pleiotropic” compound, it delivers a wide range of benefits and influences multiple systems in the body. While berberine is best known for supporting healthy blood sugar levels, it also plays a key role in various biochemical pathways associated with healthy aging and longevity.*\u003csup\u003e1-7,9-10\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eHelps maintain healthy blood sugar levels*\u003cbr\u003e\u003c\/strong\u003eBerberine is widely recognized for its role in glucose support, working through multiple pathways at once. It influences glucose absorption in the intestines, supports glucose uptake in the liver and muscles, interacts with gut microbiota, influences glucose production, and helps the body use energy efficiently. The net effect is that berberine helps maintain blood sugar levels already within the normal range.*\u003csup\u003e1-6\u003c\/sup\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eSupports cardiovascular health and lipid metabolism*\u003cbr\u003e\u003c\/strong\u003eBerberine helps maintain healthy cholesterol levels and supports blood vessels by protecting the cardiovascular system from age-related oxidative stress and inflammation. Research suggests it supports healthy blood pressure levels already within the normal range, partly by influencing nitric oxide production and helping defend against free radical damage that contributes to cardiovascular aging.*\u003csup\u003e1-6\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eSupports a balanced gut microbiome*\u003cbr\u003e\u003c\/strong\u003eAlthough berberine has low bioavailability when taken orally, research has begun to explore its benefits inside the gut. Berberine appears to act as a prebiotic-like compound, supporting beneficial gut bacteria and promoting microbial diversity. Studies suggest it influences Akkermansia muciniphila, a bacterium associated with gut barrier integrity, immune function, and metabolic health. Additionally, berberine has been shown to boost gut mucin secretion, which helps maintain a balanced microbiome and supports overall digestive and metabolic health.*\u003csup\u003e3,5,7\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eActivates AMPK, the \"longevity switch\"*\u003cbr\u003e\u003c\/strong\u003eBerberine is known to boost AMP-activated protein kinase (AMPK), which is an energy sensor that regulates metabolic changes. AMPK, which is vital for mitochondrial production, metabolic function, and cellular cleanup (autophagy). By influencing this key pathway, berberine helps optimize energy production, enhance metabolic health, and promote cellular repair, supporting the maintenance of healthy cells, DNA, and mitochondria. These effects make berberine a powerful natural compound for promoting longevity, health span, and vitality.*\u003csup\u003e1,2\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eBeyond activating the AMPK pathway, berberine has been shown to rejuvenate aging senescent cells in recent research by influencing other key longevity pathways, including PCG1-α, SIRT-1, and mTOR.*\u003csup\u003e3\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDiscover the power of Berberine—ProHealth’s trusted formula for advanced metabolic support and healthy aging, featuring TikTok’s trending botanical.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eIngredients:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eChromium:\u003c\/strong\u003e A trace mineral involved in carbohydrate metabolism and glucose utilization.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBerberine:\u003c\/strong\u003e A yellow plant alkaloid that supports healthy blood sugar levels, metabolic function, and longevity by activating AMPK.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBioPerine® Black Pepper:\u003c\/strong\u003e A patented extract that boosts the absorption and bioavailability of key ingredients.*\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eStancu AL. AMPK activation can delay aging. Discoveries (Craiova). 2015;3(4):e53. Published 2015 Dec 31. doi:10.15190\/d.2015.45\u003c\/li\u003e\n\u003cli\u003eKoppen LM, Whitaker A, Rosene A, Beckett RD. Efficacy of Berberine Alone and in Combination for the Treatment of Hyperlipidemia: A Systematic Review. J Evid Based Complementary Altern Med. 2017;22(4):956-968. doi:10.1177\/2156587216687695\u003c\/li\u003e\n\u003cli\u003eYin J, Xing H, Ye J. Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism. 2008;57(5):712-717. doi:10.1016\/j.metabol.2008.01.013\u003c\/li\u003e\n\u003cli\u003eBaziar N, Nasli-Esfahani E, Djafarian K, et al. The Beneficial Effects of Alpha Lipoic Acid Supplementation on Lp-PLA2 Mass and Its Distribution between HDL and apoB-Containing Lipoproteins in Type 2 Diabetic Patients: A Randomized, Double-Blind, Placebo-Controlled Trial. Oxid Med Cell Longev. 2020;2020:5850865. Published 2020 Mar 9. doi:10.1155\/2020\/5850865\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth style=\"font-size: 11pt; font-weight: bold;\" colspan=\"3\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003eServing Size: 1 Capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003eServings Per Container: 60\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold;\" class=\"smalltext\" colspan=\"2\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eChromium\u003cbr\u003e (as Chromium Picolinate)\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e200 mcg\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e571%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eBerberine HCl (from \u003cem\u003eBerberis\u003c\/em\u003e \u003cbr\u003e  \u003cem\u003earistata\u003c\/em\u003e Bark Extract)\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e600 mg\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eBioPerine® Black Pepper Fruit\u003cbr\u003e  Extract (95% Piperine)\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e3.4 mg\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003e† Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eRev. 09.25\u003c\/p\u003e\nBioPerine® is a registered trademark of Sabinsa, Co.\u003cbr\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eHypromellose (capsule), rice flour.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE: \u003c\/strong\u003eTake one (1) capsule 2-3 times per day with food.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION: \u003c\/strong\u003eFor use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e. Store in a cool and dry place after opening.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNOTE:\u003c\/strong\u003e Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Longevity","offers":[{"title":"Default Title","offer_id":40663981195364,"sku":"PH613","price":29.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH613_175CC_FRNT_600x600-REV0925.png?v=1764688199"},{"product_id":"prohealth-l-ergothioneine-25-mg-30-capsules-ph646","title":"L-Ergothioneine - 25 mg, 30 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003ch2\u003eErgothioneine is a powerful amino acid that helps fight the signs of aging and supports numerous aspects of health.\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports longevity by aiding in telomere length maintenence \u003csup\u003e1 \u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eCombats oxidative stress in the brain to support cognition \u003csup\u003e2\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eProtects the heart and is associated with reduced cardiovascular mortality \u003csup\u003e3\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH646_-_COA_Brighton__LOT_26052_2025-11-11_2.pdf?v=1763395761\" rel=\"noopener noreferrer\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eResearch-Supported Benefits:\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Longevity. \u003c\/strong\u003eResearch shows that ergothioneine supports longevity by protecting against accelerated telomere shortening. (1) Longer telomeres are a powerful predictor of increased lifespan and healthspan. (4)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMaintains Cellular Health.\u003c\/strong\u003e Ergothioneine has been shown to reduce levels of oxidative stress. High levels of oxidative stress may contribute to DNA damage, a decline in ATP (cellular energy) production and elevated inflammatory markers. (5)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePromotes Heart Health. \u003c\/strong\u003eBy reducing oxidative stress, ergothioneine exhibits powerful cardioprotective properties. Oxidative stress is associated with accelerated aging of heart cells, studies show ergothioneine reduces cardiac-related mortality risk. (6)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEnhances Brain Health. \u003c\/strong\u003eLow levels of ergothioneine are correlated with neurodegeneration and cognitive impairment. (7) Animal studies have found that administration of ergothioneine improves markers of memory and mood. (8)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImproves Performance. \u003c\/strong\u003eResearch suggests ergothioneine may improve markers associated with fitness and muscle health. One study found that administration ergothioneine to mice increased time to exhaustion during aerobic activity and enhanced protein synthesis post-exercise. (9)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Samuel P, Tsapekos M, de Pedro N, Liu AG, Casey Lippmeier J, Chen S. Ergothioneine Mitigates Telomere Shortening under Oxidative Stress Conditions. J Diet Suppl. 2022;19(2):212-225. doi:10.1080\/19390211.2020.1854919 \u003cbr\u003e\u003cbr\u003e2. Wijesinghe P, Whitmore CA, Campbell M, et al. Ergothioneine, a dietary antioxidant improves amyloid beta clearance in the neuroretina of a mouse model of Alzheimer's disease. Front Neurosci. 2023;17:1107436. Published 2023 Mar 14. doi:10.3389\/fnins.2023.1107436 \u003cbr\u003e\u003cbr\u003e3. Dare A, Elrashedy AA, Channa ML, Nadar A. Cardioprotective Effects and in-silico Antioxidant Mechanism of L-Ergothioneine in Experimental Type-2 Diabetic Rats. Cardiovasc Hematol Agents Med Chem. 2022;20(2):133-147. doi:10.2174\/1871525719666210809122541 \u003cbr\u003e\u003cbr\u003e4. Heidinger BJ, Blount JD, Boner W, Griffiths K, Metcalfe NB, Monaghan P. Telomere length in early life predicts lifespan. Proc Natl Acad Sci U S A. 2012;109(5):1743-1748. doi:10.1073\/pnas.1113306109 \u003cbr\u003e\u003cbr\u003e5. Fu TT, Shen L. Ergothioneine as a Natural Antioxidant Against Oxidative Stress-Related Diseases. Front Pharmacol. 2022;13:850813. Published 2022 Mar 18. doi:10.3389\/fphar.2022.850813 \u003cbr\u003e\u003cbr\u003e6. Smith E, Ottosson F, Hellstrand S, et al. Ergothioneine is associated with reduced mortality and decreased risk of cardiovascular disease. Heart. 2020;106(9):691-697. doi:10.1136\/heartjnl-2019-315485 \u003cbr\u003e\u003cbr\u003e7. Wu LY, Kan CN, Cheah IK, et al. Low Plasma Ergothioneine Predicts Cognitive and Functional Decline in an Elderly Cohort Attending Memory Clinics. Antioxidants (Basel). 2022;11(9):1717. Published 2022 Aug 30. doi:10.3390\/antiox11091717 \u003cbr\u003e\u003cbr\u003e8. Ishimoto T, Kato Y. Ergothioneine in the brain. FEBS Lett. 2022;596(10):1290-1298. doi:10.1002\/1873-3468.14271 \u003cbr\u003e\u003cbr\u003e9. Fovet T, Guilhot C, Delobel P, Chopard A, Py G, Brioche T. Ergothioneine Improves Aerobic Performance Without Any Negative Effect on Early Muscle Recovery Signaling in Response to Acute Exercise. Front Physiol. 2022;13:834597. Published 2022 Feb 9. doi:10.3389\/fphys.2022.834597 \u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-how-it-work-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003eErgothioneine is an amino acid that your body is unable to make on its own but can be obtained from eating foods such as certain types of mushrooms and organ meat.\u003c\/li\u003e\n\u003cli\u003eAs you age, levels of ergothioneine decline in the body, potentially contributing to a decline in cellular, brain, heart, and muscle health.\u003c\/li\u003e\n\u003cli\u003eErgothioneine is absorbed in the small intestine and transported throughout the body via a specific transporter known as the Organic Cation Transporter 1 (OCTN1). This transporter is highly selective for ergothioneine, allowing it to enter cells efficiently.\u003c\/li\u003e\n\u003cli\u003eOnce inside the cells, ergothioneine primarily exerts its effects as a potent antioxidant. It works by donating electrons to neutralize harmful free radicals and reactive oxygen species (ROS) that are generated during normal cellular metabolism and in response to environmental stressors.\u003c\/li\u003e\n\u003cli\u003eAdministration of ergothioneine in animal studies has been shown to reduce oxidative stress, mediate inflammatory markers, and promote cellular, brain, and heart health.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth colspan=\"3\" style=\"font-size: 11pt; font-weight: bold;\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003eServing Size: 1 Capsule\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003eServings Per Container: 30\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"2\" class=\"smalltext\" style=\"font-weight: bold;\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eL-Ergothioneine\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e25 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e†\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003e† Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV.08.25\u003cbr\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eHypromellose (capsule), rice flour.\u003cstrong\u003e \u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e Take (1) capsule per day, with or without food.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e. Store in a cool and dry place after opening.\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"summary-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnique Formulation. \u003c\/strong\u003eCompared to the majority of products on the market with lower doses, ProHealth's Ergothioneine contains a clinically effective dose of 25 mg of ergothioneine per serving.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Longevity","offers":[{"title":"Default Title","offer_id":42498338291812,"sku":"PH646","price":39.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH646_175ML_FRNT_600x600_0825.png?v=1780596479"},{"product_id":"prohealth-alpha-lipoic-acid-500-mg-60-capsules-ph644","title":"Alpha-Lipoic Acid - 500 mg per serving, 60 capsules","description":"\u003cdetails open=\"\"\u003e\n\u003ch2\u003eAlpha Lipoic Acid\u003c\/h2\u003e\n\u003cp\u003eAlpha lipoic acid (ALA) is a powerful antioxidant that safeguards each of the cells in our body, supporting longevity by reducing oxidative stress and protecting against cellular damage. Research shows alpha lipoic acid protects against age-related health decline of the heart, brain and skin.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSupports cellular health by reducing oxidative stress\u003c\/li\u003e\n\u003cli\u003ePromotes energy production by supporting mitochondrial health\u003c\/li\u003e\n\u003cli\u003eNormalizes blood sugar levels by improving insulin sensitivity\u003c\/li\u003e\n\u003cli\u003eProtects the heart from free radical damage\u003c\/li\u003e\n\u003cli\u003eEnhances cognitive health by protecting neurons from oxidative damage\u003c\/li\u003e\n\u003cli\u003eImproves skin health by aiding in collagen synthesis\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca style=\"color: #0000ff;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH644_-_COA_Brighton__LOT_2510147_2025-12-01.pdf?v=1765467299\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eResearch-Supported Benefits:\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Cellular Health. \u003c\/strong\u003eAlpha lipoic acid (ALA) functions as a powerful antioxidant, protecting each of the cells in our body from oxidative damage. (1) Studies show that oxidative damage is a key contributor to age-related health decline and decreased longevity. (2) ALA further supports cellular health by aiding in mitochondrial biogenesis (the creation of new mitochondria), which is critical for ATP (cellular energy) production. (3)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRegulates Blood Sugar.\u003c\/strong\u003e Research shows alpha lipoic acid exhibits blood-sugar regulating effects by increasing the uptake of glucose into cells and increasing insulin sensitivity. (4) A 2022 meta-analysis of 16 randomized controlled trials concluded alpha lipoic acid supplementation significantly reduces fasting blood glucose and Hemoglobin A1C. (5)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEnhances Heart Health. \u003c\/strong\u003eBy reducing oxidative stress, alpha lipoic acid offers protection against age-related decline of heart health. A 2022 randomized controlled trial involving 46 participants found that 12 weeks of alpha lipoic acid supplementation offers additional cardio-protection by significantly reducing triglycerides and total cholesterol. (6)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePromotes Cognitive Health. \u003c\/strong\u003eResearch shows that oxidative stress contributes to many of the symptoms of brain aging, including cognitive dysfunction and reduced memory. (7) Animal studies indicate alpha lipoic acid has neuroprotective effects by reducing markers of oxidative stress in the brain. (8)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImproves Skin Health. \u003c\/strong\u003eA key contributor to skin aging is the decline in collagen production that occurs after age 40. Alpha lipoic acid supports healthy collagen synthesis by aiding in the recycling of vitamin C, which is a critical nutrient that promotes collagen production within the body. The antioxidant effects of alpha lipoic acid offer further support for skin health by protecting against oxidative damage of skin cells from environmental factors.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Gianturco V, Bellomo A, D'Ottavio E, et al. Impact of therapy with alpha-lipoic acid (ALA) on the oxidative stress in the controlled NIDDM: a possible preventive way against the organ dysfunction?. Arch Gerontol Geriatr. 2009;49 Suppl 1:129-133. doi:10.1016\/j.archger.2009.09.022 \u003cbr\u003e\u003cbr\u003e2. Warraich UE, Hussain F, Kayani HUR. Aging - Oxidative stress, antioxidants and computational modeling. Heliyon. 2020;6(5):e04107. Published 2020 May 31. doi:10.1016\/j.heliyon.2020.e04107 \u003cbr\u003e\u003cbr\u003e3. Dos Santos SM, Romeiro CFR, Rodrigues CA, Cerqueira ARL, Monteiro MC. Mitochondrial Dysfunction and Alpha-Lipoic Acid: Beneficial or Harmful in Alzheimer's Disease?. Oxid Med Cell Longev. 2019;2019:8409329. Published 2019 Nov 30. doi:10.1155\/2019\/8409329 \u003cbr\u003e\u003cbr\u003e4. Capece U, Moffa S, Improta I, et al. Alpha-Lipoic Acid and Glucose Metabolism: A Comprehensive Update on Biochemical and Therapeutic Features. Nutrients. 2022;15(1):18. Published 2022 Dec 21. doi:10.3390\/nu15010018 \u003cbr\u003e\u003cbr\u003e5. Jibril AT, Jayedi A, Shab-Bidar S. Efficacy and safety of oral alpha-lipoic acid supplementation for type 2 diabetes management: a systematic review and dose-response meta-analysis of randomized trials. Endocr Connect. 2022;11(10):e220322. Published 2022 Sep 26. doi:10.1530\/EC-22-0322 \u003cbr\u003e\u003cbr\u003e6. Ahmadi M, Keshavarz SA, Abbasi B. Effects of alpha lipoic acid supplementation on serum lipid profile in patients with metabolic syndrome: A randomized, double-blind, placebo-controlled clinical trial. ARYA Atheroscler. 2022;18(4):1-8. doi:10.22122\/arya.2022.26181 \u003cbr\u003e\u003cbr\u003e7. Singh P, Barman B, Thakur MK. Oxidative stress-mediated memory impairment during aging and its therapeutic intervention by natural bioactive compounds. Front Aging Neurosci. 2022;14:944697. Published 2022 Jul 25. doi:10.3389\/fnagi.2022.944697 \u003cbr\u003e\u003cbr\u003e8. Maciejczyk M, Żebrowska E, Nesterowicz M, Żendzian-Piotrowska M, Zalewska A. α-Lipoic Acid Strengthens the Antioxidant Barrier and Reduces Oxidative, Nitrosative, and Glycative Damage, as well as Inhibits Inflammation and Apoptosis in the Hypothalamus but Not in the Cerebral Cortex of Insulin-Resistant Rats. Oxid Med Cell Longev. 2022;2022:7450514. Published 2022 Mar 29. doi:10.1155\/2022\/7450514 \u003cbr\u003e\u003cbr\u003e9. Salehi B, Berkay Yılmaz Y, Antika G, et al. Insights on the Use of α-Lipoic Acid for Therapeutic Purposes. Biomolecules. 2019;9(8):356. Published 2019 Aug 9. doi:10.3390\/biom9080356\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cfooter\u003e\n\u003cul\u003e\n\u003cli\u003eAlpha lipoic acid (ALA) is a naturally occurring compound that functions as a powerful antioxidant in the body.\u003c\/li\u003e\n\u003cli\u003eIt is both water-soluble and fat-soluble, allowing it to work in various cellular environments.\u003c\/li\u003e\n\u003cli\u003eALA is produced in small amounts within the human body and can also be obtained from food sources such as spinach, broccoli, brussels sprouts and organ and red meats.\u003c\/li\u003e\n\u003cli\u003eDue to its antioxidant effects, alpha lipoic acid decreases levels of oxidative stress and reduces symptoms of age-related health decline of the heart, brain, and skin.\u003c\/li\u003e\n\u003cli\u003eStudies show alpha lipoic aids in blood sugar regulation, which is critical for longevity and cellular health.\u003c\/li\u003e\n\u003cli\u003eALA further improves cellular health by supporting ATP production and mitochondrial biogenesis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/footer\u003e\u003cmain\u003e\n\u003ctable style=\"height: 105.283px;\" width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 20.5333px;\"\u003e\n\u003cth colspan=\"3\" style=\"font-size: 11pt; font-weight: bold; width: 99.3437%; height: 20.5333px;\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd style=\"width: 99.3437%; height: 17.15px;\" colspan=\"3\" class=\"smalltext\"\u003eServing Size: 1 Capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd style=\"width: 99.3437%; height: 17.15px;\" colspan=\"3\" class=\"smalltext\"\u003eServings Per Container: 60\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16.15px;\"\u003e\n\u003ctd colspan=\"2\" class=\"smalltext\" style=\"font-weight: bold; width: 82.5179%; height: 16.15px;\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; width: 16.8258%; height: 16.15px;\" class=\"smalltext\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd style=\"width: 54.4153%; height: 17.15px;\" class=\"smalltext\"\u003eAlpha-Lipoic Acid\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; width: 28.1026%; height: 17.15px;\" align=\"right\"\u003e500 mg\u003cbr\u003e\n\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; width: 16.8258%; height: 17.15px;\" align=\"right\"\u003e†\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd style=\"width: 99.3437%; height: 17.15px;\" colspan=\"3\" class=\"smalltext\"\u003e† Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eREV.08.25\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eHypromellose (capsule), microcrystalline cellulose, rice flour.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e Take one (1) capsule 1-2 times per day, preferably with food.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e. Store in a cool and dry place.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/main\u003e\n\u003cdiv class=\"summary\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnique Formulation. \u003c\/strong\u003eProHealth’s alpha lipoic acid was specifically formulated to reduce symptoms of age-related health decline.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEffective dosing: \u003c\/strong\u003eCompared to other brands of alpha lipoic acid on the market containing between 100 – 300 mg of ALA, ProHealth's alpha lipoic acid contains a clinically effective dose of 1,000 mg of alpha lipoic acid per serving, a dose that is supported by the latest scientific studies.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Longevity","offers":[{"title":"Default Title","offer_id":42631827751012,"sku":"PH644","price":19.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH644_175ML_FRNT_600x600_REV0825.png?v=1770129288"},{"product_id":"prohealth-pure-spermidine-1-mg-180-softgels-ph680","title":"Pure Spermidine - 1 mg, 180 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eSpermidine - A Vital Compound for Cellular Repair and Longevity* \u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eReplenish spermidine*\u003csup\u003e1\u003c\/sup\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eBoost autophagy*\u003csup\u003e1-3\u003c\/sup\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eMimic the positive effects of fasting*\u003csup\u003e2\u003c\/sup\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eOptimize healthy aging*\u003csup\u003e1-5\u003c\/sup\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca style=\"color: #0000ff;\" rel=\"noopener noreferrer\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH680-_COA_Brighton_LOT_A25H004_2025-10-06.pdf?v=1759937527\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurely Sourced:\u003c\/strong\u003e Made from purified wheat germ extract, precisely standardized for maximum spermidine content.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNever Synthetic:\u003c\/strong\u003e Formulated exclusively from natural sources to provide food-grade spermidine—free from synthetic spermidine trihydrochloride.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdeal Dosage:\u003c\/strong\u003e Each capsule delivers \"the just right dose\" of spermidine to support healthy autophagy activation.*\u003csup\u003e1-3\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTrusted Quality Since 1988:\u003c\/strong\u003e USA manufactured, 3rd-party lab tested, GMP certified for your peace of mind.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eWhat Makes Ours Better?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eLongevity Focused:\u003c\/strong\u003e We leverage cutting-edge advancements in aging research to formulate products that address the fundamental causes of aging.*\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTriple Lab Tested:\u003c\/strong\u003e Every product is tested three times by independent 3rd-party labs to ensure we meet the highest standards.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eComplete Transparency:\u003c\/strong\u003e In an industry flooded with fake supplements, we stand apart by publishing our 3rd-party lab test results. We’re committed to showing you exactly what’s in every bottle, so you can feel confident in what you’re putting into your body.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUSA Manufacturing Excellence:\u003c\/strong\u003e Made in FDA-regulated, GMP-certified facilities in the USA for the highest quality and safety standards.*\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e100-Day Risk-Free Guarantee:\u003c\/strong\u003e We stand behind our products. Not satisfied? Reach out to our Santa Barbara, CA office for a full refund within 100 days – no hassle, no questions\u003cstrong\u003e.\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSpermidine is a naturally occurring polyamine compound present in all living organisms, derived from the amino acid ornithine. It plays a crucial role in youthful cellular processes and uniquely activates autophagy, the body’s cellular cleanup mechanism. Autophagy facilitates the breakdown and recycling of old and damaged cellular components, helping to rejuvenate cell structure and function.*\u003csup\u003e1-3\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eWhile fasting and caloric restriction are the most well-known methods for activating autophagy, supplementing with spermidine provides a groundbreaking alternative that mimics the benefits of fasting, effectively “turning on” autophagy without the need for caloric restriction.*\u003csup\u003e1-3\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eProHealth Pure Spermidine offers a pure, vegan, and non-GMO source of this powerful compound, supporting the body’s natural cellular renewal processes. For best results, we recommend taking 1 to 3 capsules with your evening meal to jump-start an overnight fast or with breakfast to extend the benefits of your overnight fasting period.*\u003csup\u003e2\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eSpermidine - A Vital Compound for Cellular Repair and Longevity*\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBoost autophagy (cellular clean-up)*\u003csup\u003e1-3\u003c\/sup\u003e\u003c\/strong\u003e\u003cbr\u003eSpermidine acts directly on our cells to restore them to a healthy state. It works by inducing autophagy - a process that keeps our cells working more efficiently by removing damaged parts of the cell and repairing cellular function.*\u003csup\u003e1-3\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMimic the positive effects of fasting*\u003csup\u003e2\u003c\/sup\u003e\u003c\/strong\u003e\u003cbr\u003eWhen we fast - extend the time between meals - spermidine levels increase, activating cellular repair and restoration processes that promote healthy aging. Supplementing with spermidine can mimic key aspects of the fasting state, allowing your body to experience its healthy aging benefits.*\u003csup\u003e2\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOptimize healthy aging*\u003c\/strong\u003e\u003cbr\u003eSpermidine intake is associated with a healthy life span and may support up to nine hallmarks of aging. A research study showed that people who consume more spermidine are likely to live longer, compared to those who consume lower levels.  And research shows that supplementing with spermidine can help preserve the length of telomeres - the regions of DNA that shorten as you age.*\u003csup\u003e1,4\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOrder now and join the 200,000+ people who trust ProHealth\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eIngredients:\u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eWheat germ extract:\u003c\/strong\u003e \u003cem\u003e(Triticum aestivum)\u003c\/em\u003e: A concentrated food source of spermidine.\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003csup\u003e1\u003c\/sup\u003e Hofer et al. Nat Aging. 2022 Dec 22;2(12):1112-1129. \u003cbr\u003e\u003csup\u003e2\u003c\/sup\u003e Hofer et al. Nat Cell Biol. 2024 Sep;26(9):1571-1584. \u003cbr\u003e\u003csup\u003e3\u003c\/sup\u003e Madeo et al. Autophagy. 2019 Jan;15(1):165–168. \u003cbr\u003e\u003csup\u003e4\u003c\/sup\u003e Kiechl et al. Am J Clin Nutr. 2018 Aug 1;108(2):371-380.  \u003cbr\u003e\u003csup\u003e5\u003c\/sup\u003e Wirth et al. Geroscience. 2021 Apr;43(2):673-690.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\" style=\"height: 216.533px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 20.5333px;\"\u003e\n\u003cth colspan=\"3\" style=\"font-size: 11pt; font-weight: bold;\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 19.6px;\"\u003eServing Size: 1 Capsule\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 19.6px;\"\u003eServings Per Container: 180\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd colspan=\"2\" class=\"smalltext\" style=\"font-weight: bold;\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19.6px;\"\u003eSpermidine (From Wheat Germ Extract)\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e1 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e†\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 19.6px;\"\u003e† Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eREV.09.24\u003c\/p\u003e\n\u003cp\u003eNu-FLOW® is a registered trademark of Ribus Inc.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eVegetable cellulose (capsule), microcrystalline cellulose, Nu-Flow® (rice hulls).\u003cstrong\u003e \u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCONTAINS: \u003c\/strong\u003eWheat.\u003cstrong\u003e \u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e Take one (1) to three (3) capsules with your last meal to start an overnight fast, or with breakfast to extend its benefits, or as directed by your healthcare professional.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNOTE:\u003c\/strong\u003e Store in a cool, dry place, away from direct sunlight. Do not use if tamper evident seal is broken or missing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN.\u003c\/strong\u003e Store in a cool and dry place after opening.\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Longevity","offers":[{"title":"Default Title","offer_id":51677671522670,"sku":"PH680","price":29.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH680_FRNT_250ML_600x600_fcd35bcc-1f88-42fe-b210-757eb3aff74d.png?v=1738180371"},{"product_id":"prohealth-full-spectrum-ashwagandha-60-capsules-ph634","title":"Full Spectrum Ashwagandha -  60 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eThe Serenity Strengthener – For Stress Resilience* \u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHelps the body adapt to everyday stress*\u003csup\u003e1,2\u003c\/sup\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eEases occasional anxiety and nervousness*\u003csup\u003e1,2\u003c\/sup\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eEnhances sleep quality*\u003csup\u003e5\u003c\/sup\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003ePromotes a balanced mood*\u003csup\u003e1,2\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eBoosts cognitive performance*\u003csup\u003e3,4\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH634_-_Qalitex_COA_LOT_PH1034_2024-11-15_1.pdf?v=1734477445\" rel=\"noopener noreferrer\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnergetic Properties:\u003c\/strong\u003e In Ayurvedic tradition, Ashwagandha is described as warming, calming, grounding, and oily, which makes this unique botanical particularly beneficial for restoring Vata imbalances (e.g., coldness, nervous energy, and dry skin), reducing stress, and promoting mental stability.* \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFull Spectrum Blend:\u003c\/strong\u003e This formula contains the full spectrum of root-only bioactive constituents, which aligns with Ashwagandha’s traditional use and where its most powerful adaptogenic effects are found.* \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExpertly Developed:\u003c\/strong\u003e Designed by a team of doctors and scientists with deep expertise in adaptogens and full-spectrum botanicals to ensure maximum potency and efficacy.*\u003csup\u003e1,2\u003c\/sup\u003e \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinically Researched:\u003c\/strong\u003e KSM-66 Ashwagandha is the most clinically studied Ashwagandha on the market, consistently showing its safety and efficacy.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTrusted Quality Since 1988:\u003c\/strong\u003e USA manufactured, 3\u003csup\u003erd\u003c\/sup\u003e-party lab tested, GMP certified for your peace of mind.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eWhat Makes Ours Better?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eLongevity Focused:\u003c\/strong\u003e We leverage cutting-edge advancements in aging research to formulate products that address the fundamental causes of aging.*\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTriple Lab Tested:\u003c\/strong\u003e Every product is tested three times by independent 3\u003csup\u003erd\u003c\/sup\u003e-party labs to ensure we meet the highest standards.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eComplete Transparency:\u003c\/strong\u003e In an industry flooded with fake supplements, we stand apart by publishing our 3rd-party lab test results. We’re committed to showing you exactly what’s in every bottle, so you can feel confident in what you’re putting into your body.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUSA Manufacturing Excellence:\u003c\/strong\u003e Made in FDA-regulated, GMP-certified facilities in the USA for the highest quality and safety standards.*\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e100-Day Risk-Free Guarantee:\u003c\/strong\u003e We stand behind our products. Not satisfied? Reach out to our Santa Barbara, CA office for a full refund within 100 days – no hassle, no questions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAshwagandha (\u003cem\u003eWithania somnifera\u003c\/em\u003e) is the ultimate adaptogen—an extraordinary botanical that helps the body adapt to physical, emotional, and environmental stress, while promoting balance and enhancing overall performance. Adaptogens work by regulating the body’s stress response, whether overactive or underactive, to restore stability and build resilience.* \u003csup\u003e1-3\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eWhat’s incredibly unique about Ashwagandha is its dual-action benefits—it has both calming and energetic effects, while most other adaptogens have one or the other. Whether you're seeking a calm relaxing energy, or deep invigorating energy, Ashwagandha adapts to support your needs.*\u003c\/p\u003e\n\u003cp\u003eBeyond its powerful stress-reducing effects, Ashwagandha is also known for supporting a healthy immune system, optimizing adrenal function, promoting restful sleep, improving cognitive function, enhancing sexual function and more. It works by supporting GABA—a neurotransmitter that inhibits excessive neuronal stimulation—to help balance brain activity and regulate the hypothalamic-pituitary-adrenal (HPA) axis, a key neuroendocrine system that manages the body’s response to stress.*\u003csup\u003e1-7\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eThe Serenity Strengthener – For Stress Resilience*\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHelps the body adapt to everyday stress*\u003csup\u003e1\u003c\/sup\u003e\u003c\/strong\u003e\u003cbr\u003eDaily stressors can accumulate in the body and lead to hormone and brain dysregulation. Ashwagandha modulates stress hormones and brain activity to bring the body back into balance. A clinical study showed that KSM-66 Ashwagandha—taken 250 mg\/day or 600 mg\/day for 8 weeks—significantly decreased cortisol levels and feelings of stress.*\u003csup\u003e1\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEases occasional anxiety and nervousness*\u003csup\u003e1,2\u003c\/sup\u003e\u003c\/strong\u003e\u003cbr\u003eAs Ashwagandha helps the body adapt to stress, it also calms anxious feelings that come with it. Clinical studies show that KSM-66 Ashwagandha supports the management of anxiety and improves quality of life, by lowering levels of cortisol and altering how stress is perceived.*\u003csup\u003e1-2\u003c\/sup\u003e\u003csup\u003e\u003cbr\u003e\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEnhances sleep quality*\u003csup\u003e5\u003c\/sup\u003e\u003c\/strong\u003e\u003cbr\u003eQuality of sleep improves when the body is in a more relaxed state—KSM-66 Ashwagandha supports both. A clinical study showed that after 10 weeks of taking 600 mg of KSM-66 Ashwagandha per day (two doses of 300 mg) both sleep quality and onset latency improved, along with a decrease in anxiety that likely contributed to its effects.*\u003csup\u003e5\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOrder now and join the 200,000+ people who trust ProHealth Full Spectrum Ashwagandha for their cellular health!  \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eIngredients:\u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAshwagandha:\u003c\/strong\u003e (\u003cem\u003eWithania somnifera\u003c\/em\u003e): A dual-action adaptogen—both deeply energizing and calming—that’s traditionally used for vitality and rejuvenation.*\u003csup\u003e8\u003c\/sup\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003csup\u003e1\u003c\/sup\u003e Salve et al. \u003cem\u003eCureus\u003c\/em\u003e. 2019 Dec 25;11(12):e6466. \u003cbr\u003e\u003csup\u003e2\u003c\/sup\u003e Chandrasekhar et al. \u003cem\u003eIndian J Psychol Med.\u003c\/em\u003e 2012 Jul;34(3):255-62.    \u003cbr\u003e\u003csup\u003e3\u003c\/sup\u003e Kelgane et al. \u003cem\u003eCureus\u003c\/em\u003e. 2020 Feb 23;12(2):e7083.\u003cbr\u003e\u003csup\u003e4\u003c\/sup\u003e Choudhary et al. \u003cem\u003eJ Diet Suppl.\u003c\/em\u003e 2017 Nov 2;14(6):599-612.   \u003cbr\u003e\u003csup\u003e5\u003c\/sup\u003e Langade et al. \u003cem\u003eCureus.\u003c\/em\u003e 2019 Sep 28;11(9):e5797.   \u003cbr\u003e\u003csup\u003e6\u003c\/sup\u003e Ajgaonkar et al. \u003cem\u003eCureus.\u003c\/em\u003e 2022 Oct 28;14(10):e30787.  \u003cbr\u003e\u003csup\u003e7\u003c\/sup\u003e Chauhan et al. \u003cem\u003eHealth Sci Rep.\u003c\/em\u003e 2022 Jul 20;5(4):e741.   \u003cbr\u003e\u003csup\u003e8\u003c\/sup\u003e Singh et al. \u003cem\u003eAfr J Tradit Complement Altern Med.\u003c\/em\u003e 2011 Jul 3;8(5 Suppl):208–213.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\" style=\"height: 216.533px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 20.5333px;\"\u003e\n\u003cth colspan=\"3\" style=\"font-size: 11pt; font-weight: bold;\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 19.6px;\"\u003eServing Size: 2 Capsule\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 19.6px;\"\u003eServings Per Container: 30\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd colspan=\"2\" class=\"smalltext\" style=\"font-weight: bold;\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19.6px;\"\u003eKSM-66® Organic Ashwagandha (\u003cem\u003eWithania somnifera\u003c\/em\u003e) Root Extract (5% withanolides)\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e600 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e†\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19.6px;\"\u003eOrganic Ashwagandha (\u003cem\u003eWithania somnifera\u003c\/em\u003e) Root Powder\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e300 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e†\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19.6px;\"\u003eAshwagandha (\u003cem\u003eWithania somnifera\u003c\/em\u003e) Root Extract (2.5% withanolides)\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e200 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e†\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 19.6px;\"\u003e† Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eREV.10.24\u003c\/p\u003e\n\u003cp\u003eKSM-66® is a registered trademark of Ixoreal Biomed Inc.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eVegetable cellulose (capsule), rice flour.\u003cstrong\u003e \u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e Take two (2) capsules daily, or as recommended by your healthcare professional.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or undergoing treatment for a  medical condition. Do not exceed the suggested use. KEEP OUT OF REACH OF CHILDREN. Store in a cool and dry place after opening.\u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Longevity","offers":[{"title":"Default Title","offer_id":51724469764462,"sku":"PH634","price":17.97,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH634_FRNT_175CC_600x600_Rev1024_46dfb46e-0344-4b57-b9ff-066dc41832c4.png?v=1738176389"},{"product_id":"prohealth-full-spectrum-apigenin-plus-60-capsules-ph695","title":"Full Spectrum Apigenin Plus - 250 mg, 60 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eHarness the Power of Apigenin for Healthy Aging \u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHelps maintain healthy NAD+ levels*\u003csup\u003e1-3\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eProvides antioxidant support to combat oxidative stress*\u003csup\u003e4-7\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eSupports relaxation and sleep quality*\u003csup\u003e8-13\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eTargets key pathways of healthy aging at the cellular level*\u003csup\u003e14-29\u003c\/sup\u003e*\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eApigenin is a potent flavonoid commonly found in chamomile, parsley, and celery that plays a key role in cellular health, relaxation, and longevity. By targeting CD38, a major NAD+-consuming enzyme, apigenin helps sustain optimal NAD+ levels—essential for energy production and healthy aging.*\u003csup\u003e1-3\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH695_-_COA_Brighton_LOT_PH1040_2025.01.24.pdf?v=1740177130\" rel=\"noopener noreferrer\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eUltra-Pure Extract:\u003c\/strong\u003e Apigenin derived from celery (Apium graveolens) seed, delivering exceptional purity and potency, rooted in centuries of traditional use.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinically Backed Strength:\u003c\/strong\u003e Each capsule provides a potent 250mg dose of apigenin, among the highest available on the market.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFull Spectrum Ingredients:\u003c\/strong\u003e Unlike synthetic apigenin, this blend combines pure plant-derived apigenin with organic parsley powder to deliver a wide spectrum of phytonutrients and co-factors that support optimal activity.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnhanced Absorption:\u003c\/strong\u003e Features BioPerine® black pepper extract to boost absorption and bioavailability.*\u003csup\u003e30\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eWhat Makes Ours Better?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDoctor-Formulated:\u003c\/strong\u003e Developed by our in-house science team in collaboration with leading wellness experts to address the root causes of aging.* \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTriple Lab Tested:\u003c\/strong\u003e Subjected to three rounds of independent third-party lab testing to ensure unmatched potency and purity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFull Transparency:\u003c\/strong\u003e In an industry full of misleading claims, we publish our third-party lab results—so you always know exactly what’s in every bottle.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUSA Manufacturing Excellence:\u003c\/strong\u003e Made in FDA-regulated, GMP-certified facilities in the USA for the highest quality and safety standards.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e100-Day Risk-Free Guarantee:\u003c\/strong\u003e We're confident you’ll love our product. If you're not satisfied, contact our Santa Barbara, CA office for a full refund within 100 days—no hassle, no questions asked. \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eApigenin is a naturally occurring flavonoid found in a variety of fruits, vegetables, and herbs. Its therapeutic potential is highlighted by human clinical studies on chamomile extract, which contains apigenin as a key active ingredient. Recognized for its broad-spectrum benefits, apigenin has gained attention for its role in supporting relaxation and sleep quality. It interacts with GABA receptors in the brain, helping to foster a calm state of mind and support healthy sleep patterns—critical factors for long-term health and cognitive function.*\u003csup\u003e31\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eOne of apigenin's key mechanisms involves targeting CD38, an enzyme responsible for depleting NAD+, a vital molecule for energy production and cellular repair. By balancing CD38 activity, apigenin helps maintain healthy NAD+ levels, supporting mitochondrial function, DNA integrity, and overall cellular resilience as the body ages. Additionally, apigenin offers powerful antioxidant effects, neutralizing free radicals and reducing oxidative stress—both major contributors to aging and age-related decline.*\u003csup\u003e1-3\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eBy addressing several hallmarks of aging and supporting the core pillars of health, apigenin emerges as a powerful compound for those aiming to optimize their health and longevity.*\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eFeel the Difference with Full Spectrum Apigenin\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHelps maintain healthy NAD+ levels*\u003cbr\u003e\u003c\/strong\u003eApigenin indirectly boosts NAD+ levels by targeting CD38, a glycoprotein that consumes NAD+ during cellular processes. Research shows that mice either lacking CD38 or supplemented with apigenin have approximately 50% higher NAD+ levels, underscoring apigenin’s role in NAD+ metabolism. As CD38 activity naturally increases with age, accelerating NAD+ decline, apigenin offers a unique way to counteract this process. When paired with NAD+ precursors like NR or NMN, apigenin further optimizes NAD+ metabolism, providing additional support for cellular health and vitality.*\u003csup\u003e1-3\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProvides antioxidant support to combat oxidative stress*\u003c\/strong\u003e\u003cbr\u003eApigenin, like other powerful flavonoids such as quercetin, rutin, luteolin, and EGCG, offers robust antioxidant protection, helping plants combat UV radiation, environmental stress, and free radicals. In the human body, apigenin’s electron-rich flavonoid structure performs a similar protective function—neutralizing free radicals and boosting antioxidant pathways. This support helps promote cellular health, longevity, and overall resilience against oxidative damage.*\u003csup\u003e4-7\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports relaxation and sleep quality*\u003c\/strong\u003e\u003cbr\u003eApigenin is well-known for its ability to support relaxation and sleep quality. Research shows that higher dietary apigenin intake is linked to better sleep quality. It works by activating chloride ion channels and modulating GABAergic pathways in the brain, helping to calm neuronal activity and induce a deeper state of relaxation. Additionally, apigenin plays a role in supporting healthy cortisol levels, reducing the impact of stress and encouraging balanced, restorative sleep patterns.*\u003csup\u003e8-13\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTargets key pathways of healthy aging at the cellular level*\u003c\/strong\u003e\u003cbr\u003eBeyond its role in maintaining NAD+ levels—and its downstream activation of sirtuins and PARPs—apigenin plays a crucial part in cellular renewal. It helps activate autophagy, the body's natural cellular repair process that maintains healthy cell function. Additionally, apigenin has been shown to combat cellular senescence by acting as a senolytic agent, aiding in the clearance of senescent cells while buffering the effects of senescence-associated secretory phenotype (SASP) factors.*\u003csup\u003e14,15\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eBeyond these core actions, apigenin influences numerous other longevity pathways, including AMPK, PPARα\/γ, SIRT-1, mTOR, IGF-1, immune signaling, and NF-κB, helping to optimize cellular health across multiple systems.*\u003csup\u003e16-29\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNew and noteworthy\u003c\/strong\u003e\u003cbr\u003eApigenin is highly active in the body, with emerging research highlighting its potential to provide a range of benefits, including neuroprotection, cardiovascular support, and metabolic health. Scientists are actively exploring its full therapeutic profile.*\u003csup\u003e1,17,20,28,32-36\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eExperience nature's calming bioflavonoid—the perfect stack to elevate your wellness routine.* \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOrder now and join the thousands of people who trust ProHealth for their longevity journey!\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eIngredients:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eApigenin:\u003c\/strong\u003e A powerful bioflavonoid compound found in chamomile, known for its ability to support relaxation and boost NAD+.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrganic Parsley:\u003c\/strong\u003e A source of complementary phytonutrients that amplify the full-spectrum benefits of the formula.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBioPerine® Black Pepper:\u003c\/strong\u003e A patented extract that boosts the absorption and bioavailability of key ingredients.*\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003csup\u003e1 \u003c\/sup\u003eEscande C et al. \u003cem\u003eDiabetes\u003c\/em\u003e. 2013;62(4):1084-1093. \u003cbr\u003e\u003csup\u003e2 \u003c\/sup\u003eOgura Y et al. \u003cem\u003eAging\u003c\/em\u003e.12(12), 11325–11336.\u003cbr\u003e\u003csup\u003e3 \u003c\/sup\u003eKellenberger E et al. \u003cem\u003eBioorg Med Chem Lett\u003c\/em\u003e. 2011;21(13):3939-3942. \u003cbr\u003e\u003csup\u003e4 \u003c\/sup\u003eAhmad A et al. \u003cem\u003eFood Chem Toxicol\u003c\/em\u003e. 2019;127:218-227.\u003cbr\u003e\u003csup\u003e5 \u003c\/sup\u003eAbid R et al. \u003cem\u003eMolecules\u003c\/em\u003e. 2022;27(13):4304. \u003cbr\u003e\u003csup\u003e6 \u003c\/sup\u003eKashyap P et al. \u003cem\u003eJ Food Biochem\u003c\/em\u003e. 2022;46(4). \u003cbr\u003e\u003csup\u003e7 \u003c\/sup\u003eSingh A et al. \u003cem\u003eCrit Rev Food Sci Nutr\u003c\/em\u003e. 2024;8(17):1-37.\u003cbr\u003e\u003csup\u003e8 \u003c\/sup\u003eKim J et al. \u003cem\u003eArchives of Pharmacal Research\u003c\/em\u003e. 35(2), 367–373. \u003cbr\u003e\u003csup\u003e9 \u003c\/sup\u003eAmsterdam JD et al. \u003cem\u003eJ Clin Psychopharmacol\u003c\/em\u003e. 2009;29(4):378-382. \u003cbr\u003e\u003csup\u003e10 \u003c\/sup\u003eGodos J et al. \u003cem\u003eNutrients.\u003c\/em\u003e 2020;12(5):1226. \u003cbr\u003e\u003csup\u003e11 \u003c\/sup\u003eViola H et al. \u003cem\u003ePlanta Med\u003c\/em\u003e. 1995;61(3):213-216.\u003cbr\u003e\u003csup\u003e12 \u003c\/sup\u003eOhno S et al. \u003cem\u003eJ Steroid Biochem Mol Biol.\u003c\/em\u003e 2002;80(3):355-363. \u003cbr\u003e\u003csup\u003e13 \u003c\/sup\u003eCheng LC et al. \u003cem\u003eToxicol Appl Pharmacol.\u003c\/em\u003e 2012;258(3):343-350.\u003cbr\u003e\u003csup\u003e14 \u003c\/sup\u003eLu J et al. \u003cem\u003eFood Funct\u003c\/em\u003e. 2020;11(10):9208-9215.\u003cbr\u003e\u003csup\u003e15 \u003c\/sup\u003eFan X et al. \u003cem\u003eInt J Mol Sci\u003c\/em\u003e. 2022;23(4):2176.\u003cbr\u003e\u003csup\u003e16 \u003c\/sup\u003eChoi WH et al. \u003cem\u003eMol Nutr Food Res\u003c\/em\u003e. 2017;61.\u003cbr\u003e\u003csup\u003e17 \u003c\/sup\u003eWong TY et al. Biomed Pharmacother. 2017;96:1000–1007.\u003cbr\u003e\u003csup\u003e18 \u003c\/sup\u003eOno K et al. \u003cem\u003eJ Agric Food Chem\u003c\/em\u003e. 2011;59:13346–13352. \u003cbr\u003e\u003csup\u003e19 \u003c\/sup\u003eWei X et al. \u003cem\u003eClin Sci\u003c\/em\u003e. 2017;131:567–581. \u003cbr\u003e\u003csup\u003e20 \u003c\/sup\u003eMahajan UB et al. \u003cem\u003eInt J Mol Sci\u003c\/em\u003e. 2017;18.\u003cbr\u003e\u003csup\u003e21 \u003c\/sup\u003eWang F et al. \u003cem\u003eChem Biol Interact.\u003c\/em\u003e 2017;275:171–177. \u003cbr\u003e\u003csup\u003e22 \u003c\/sup\u003eYu W et al. \u003cem\u003eEvid Based Complement Alternat Med.\u003c\/em\u003e 2017;2017:2590676.\u003cbr\u003e\u003csup\u003e23 \u003c\/sup\u003eTong X et al. \u003cem\u003eMol Carcinog.\u003c\/em\u003e 2012;51:268–279. \u003cbr\u003e\u003csup\u003e24 \u003c\/sup\u003eBridgeman BB et al. \u003cem\u003eCell Signal\u003c\/em\u003e. 2016;28:460–468. \u003cbr\u003e\u003csup\u003e25 \u003c\/sup\u003eBabcook MA et al. \u003cem\u003eCurr. Drug Targets.\u003c\/em\u003e 2012.\u003cbr\u003e\u003csup\u003e26 \u003c\/sup\u003eShukla S et al. \u003cem\u003ePharm Res.\u003c\/em\u003e 2012;29:1506–1517.  \u003cbr\u003e\u003csup\u003e27 \u003c\/sup\u003eCardenas H et al. \u003cem\u003eInt J Mol Sci\u003c\/em\u003e. 2016;17:323. \u003cbr\u003e\u003csup\u003e28 \u003c\/sup\u003eRen B et al. \u003cem\u003eEur J Pharmacol\u003c\/em\u003e. 2016;773:13–23.\u003cbr\u003e\u003csup\u003e29 \u003c\/sup\u003eKim A et al. \u003cem\u003eArch Pharmacol\u003c\/em\u003e. 2018;391:271–283.\u003cbr\u003e\u003csup\u003e30 \u003c\/sup\u003eDudhatra GB et al. \u003cem\u003eScientific World Journal\u003c\/em\u003e. 2012;2012:637953. \u003cbr\u003e\u003csup\u003e31 \u003c\/sup\u003eKramer DJ et al. \u003cem\u003eFront Nutr\u003c\/em\u003e. 2024;11:1359176. \u003cbr\u003e\u003csup\u003e32 \u003c\/sup\u003eNabavi SF et al. \u003cem\u003ePharmacol Res\u003c\/em\u003e. 2018;128:359-365. \u003cbr\u003e\u003csup\u003e33 \u003c\/sup\u003eHan Y et al. J. \u003cem\u003eClin. Neurosci.\u003c\/em\u003e 2017;40:157–162.\u003cbr\u003e\u003csup\u003e34 \u003c\/sup\u003eZhang F et al. \u003cem\u003eNeurol Sci.\u003c\/em\u003e 2014;35:583–588. \u003cbr\u003e\u003csup\u003e35 \u003c\/sup\u003eZhao L et al. \u003cem\u003eMolecules.\u003c\/em\u003e 2013;18:9949–9965.  \u003cbr\u003e\u003csup\u003e36 \u003c\/sup\u003eJung UJ et al. \u003cem\u003eNutrients.\u003c\/em\u003e 2016;8(5):305. \u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\" style=\"height: 275.333px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 20.5333px;\"\u003e\n\u003cth style=\"font-size: 11pt; font-weight: bold; height: 20.5333px;\" colspan=\"3\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\" style=\"height: 19.6px;\"\u003eServing Size: 1 Capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\" style=\"height: 19.6px;\"\u003eServings Per Container: 60\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd style=\"font-weight: bold; height: 19.6px;\" class=\"smalltext\" colspan=\"2\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 19.6px;\" class=\"smalltext\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19.6px;\"\u003eOrganic Parsley Powder (\u003cem\u003ePetroselinum crispum\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 19.6px;\" class=\"smalltext\" align=\"right\"\u003e350 mg\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 19.6px;\" class=\"smalltext\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19.6px;\"\u003eNatural Apigenin (\u003cem\u003eApium graveolens\u003c\/em\u003e extract 98%)\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 19.6px;\" class=\"smalltext\" align=\"right\"\u003e250 mg\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 19.6px;\" class=\"smalltext\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19.6px;\"\u003eBlack Pepper (piperine) (\u003cem\u003ePiper nigrum\u003c\/em\u003e extract 95%)\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 19.6px;\" class=\"smalltext\" align=\"right\"\u003e3.5 mg\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 19.6px;\" class=\"smalltext\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\" style=\"height: 19.6px;\"\u003e†Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV.10.24\u003cbr\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE: \u003c\/strong\u003eTake one (1) capsule daily with food, or as recommended by your healthcare professional.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS\u003c\/strong\u003e:\u003cstrong\u003e \u003c\/strong\u003eVegetable cellulose (capsule). \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDOES NOT CONTAIN\u003c\/strong\u003e:\u003cstrong\u003e \u003c\/strong\u003eDairy, egg, soy, wheat, gluten, corn, fish, shellfish, tree nuts, peanuts.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION: \u003c\/strong\u003eFor use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e. Store in a cool and dry place after opening.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Longevity","offers":[{"title":"Default Title","offer_id":51870136238446,"sku":"PH695","price":45.74,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH695_175CC_FRNT_600x600-REV-1024.png?v=1740092499"}],"url":"https:\/\/www.prohealth.com\/collections\/save-30-build-your-nmn-stack.oembed","provider":"ProHealth.com","version":"1.0","type":"link"}