{"title":"Save 30% on Sirtuin Activating Supplements","description":"","products":[{"product_id":"prohealth-sirtuin-6-activator-60-capsules-ph664","title":"Sirtuin 6 Activator - 60 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eSirtuin 6 Activator: Inspired by the Blue Zones \u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eActivates sirtuin 6 (SIRT6)\u003csup\u003e1,4,6,7*\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eProvides “Blue Zone” bioactives*\u003csup\u003e5,6 \u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eSupports multiple longevity pathways*\u003csup\u003e5 \u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eNeutralizes free radicals*\u003csup\u003e5,12\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eSupports a healthy immune system \u0026amp; inflammatory response* \u003csup\u003e8,5,9-11\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca style=\"color: #0000ff;\" rel=\"noopener noreferrer\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH664_-_COA_Qalitex_LOT_A24L017_2025-02-11.pdf?v=1742594505\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eNot all fucoidan is created equal. After three years of extensive research and testing, we've finally sourced an authentic \u003cem\u003eFucus vesiculosus\u003c\/em\u003e—a special type of seaweed renowned for its powerful fucoidan content and abundant marine polyphenols. This premium seaweed extract sets a new benchmark in longevity science.* \u003csup\u003e2,5,8,13,21,22,25\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eWhat Makes Ours Better?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFucoidan-Rich Seaweed:\u003c\/strong\u003e We deliver pure, concentrated seaweed—not synthetic compounds or low-quality extracts—packed with fucoidan, a potent SIRT6 activator.*\u003csup\u003e21,22\u003c\/sup\u003e \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLongevity Boost:\u003c\/strong\u003e Each serving provides a full 400mg dose of fucoidan, the scientifically-backed compound for healthy aging.*\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFull Spectrum Support:\u003c\/strong\u003e Our formula blends whole-plant seaweed powder with high-potency extracts, offering a more complete range of bioactive compounds to amplify fucoidan’s anti-aging potential.*\u003csup\u003e12,15\u003c\/sup\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMaximized Bioactivity:\u003c\/strong\u003e Unlike many seaweed extracts that lose potency through harsh processing, our fucoidan is gently extracted using a specialized water-based method, preserving its full molecular structure for optimal effectiveness.*\u003csup\u003e5\u003c\/sup\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eWhy Choose ProHealth?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDoctor-Formulated:\u003c\/strong\u003e Developed by our in-house science team in collaboration with leading wellness experts to address the root causes of aging.*\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTriple Lab Tested:\u003c\/strong\u003e Subjected to three rounds of independent third-party lab testing to ensure unmatched potency and purity.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFull Transparency:\u003c\/strong\u003e In an industry full of misleading claims, we publish our third-party lab results—so you always know exactly what’s in every bottle.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eManufactured in the USA:\u003c\/strong\u003e Made in FDA-regulated, GMP-certified facilities, adhering to the highest quality and safety standards.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e100-Day Risk-Free Guarantee:\u003c\/strong\u003e We’re confident you’ll love our product. If you’re not satisfied, contact our Santa Barbara, CA office for a full refund within 100 days—no hassle, no questions asked.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eNot all fucoidan is created equal. \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor centuries, Japan—home to one of the world’s longest-living populations—has relied on seaweed as a dietary staple, prized for its powerful antioxidants and cellular-protective compounds. Research consistently links regular seaweed consumption to enhanced health and longevity, reinforcing its vital role in healthy aging.*\u003csup\u003e15\u003c\/sup\u003e\u003c\/p\u003e\nBuilding on this tradition, \u003cstrong\u003eSirtuin 6 Activator\u003c\/strong\u003e delivers fucoidan, one of seaweed’s most potent bioactive compounds. Naturally found in the cell walls of brown seaweed, fucoidan is clinically recognized for its ability to activate SIRT6, a key enzyme that supports healthy aging at the cellular level.*\u003csup\u003e1\u003c\/sup\u003e\n\u003cp\u003e\u003cbr\u003eBy activating SIRT6, this fucoidan-rich formula goes beyond simple antioxidant support to revitalize cellular health at its core. Research shows that increased SIRT6 activity can aid in DNA repair, boost genomic stability, and support a healthy systemic inflammatory response—processes linked to longevity in Blue Zone populations.*\u003csup\u003e5,8,9,12,14,16\u003c\/sup\u003e\u003c\/p\u003e\nEmerging studies further suggest that higher SIRT6 activity correlates with longer lifespans in multiple animal species. Scientists are now exploring its potential for brain aging, heart health, and overall longevity, with human trials underway to further uncover its impact on healthy aging.*\u003csup\u003e20,26-28\u003c\/sup\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003e\u003cbr\u003eSirtuin 6 Activator: Inspired by the Blue Zones \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAging is associated with cellular changes, including DNA damage, inflammation, and metabolic shifts, all of which have been studied in relation to SIRT6’s biological functions. Research suggests that SIRT6 plays a role in key cellular processes that support overall health.*\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupports DNA Repair\u003c\/strong\u003e – SIRT6 stabilizes the genome by repairing double-strand breaks and maintaining telomere integrity, reducing genetic instability, a major hallmark of aging.*\u003csup\u003e6\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInfluences Metabolic Balance\u003c\/strong\u003e – SIRT6 shifts cells away from inefficient sugar metabolism and toward fat oxidation, mimicking the anti-aging effects of caloric restriction.*\u003csup\u003e17\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClears Senescent Cells\u003c\/strong\u003e – Fucoidan acts as a potential senolytic, helping the body remove dysfunctional cells that drive aging.*\u003csup\u003e4,13,19\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtects Mitochondria\u003c\/strong\u003e – SIRT6 supports healthy cellular energy production, safeguarding from oxidative stress so cells can generate energy efficiently.*\u003csup\u003e5\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eNeutralizes Free Radicals* \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eOxidative stress occurs when free radicals accumulate and damage cells, proteins, and DNA—a primary driver of aging. ProHealth Sirtuin 6 Activator combats oxidative damage through multiple pathways:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDirectly Scavenges Free Radicals\u003c\/strong\u003e – Fucoidan’s unique sulfated polysaccharide structure binds to and neutralizes reactive oxygen species (ROS) before they can harm cells.*\u003csup\u003e12\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProvides Antioxidant Support\u003c\/strong\u003e – This formula combines fucoidan with polyphloroglucinols, marine polyphenols that strengthen cellular defenses against oxidative damage.*\u003csup\u003e5\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnhances Cellular Antioxidant Pathways\u003c\/strong\u003e – By enhancing glutathione and superoxide dismutase (SOD) levels, SIRT6 supports the body’s natural ability to maintain oxidative homeostasis.*\u003csup\u003e12\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eSupports a Healthy Immune System \u0026amp; Inflammatory Response* \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eHealthy immune system and inflammatory responses are essential for long-term health and longevity. Research suggests that fucoidan and SIRT6 may help support immune function and inflammation balance through multiple pathways:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupports Immune Cell Activity\u003c\/strong\u003e – Fucoidan supports the activity of macrophages, natural killer (NK) cells, and lymphocytes, helping to maintain a robust immune system and clear damaged cells.*\u003csup\u003e5,8,10\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHelps Maintain a Healthy Inflammatory Response\u003c\/strong\u003e – SIRT6 influences cytokine activity and inflammatory response mechanisms, helping to support healthy inflammation for optimal aging.* \u003csup\u003e5,8,9\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnhances Gut-Immune Function\u003c\/strong\u003e – Fucoidan supports a healthy gut microbiome, which is closely linked to immune and inflammatory balance.*\u003csup\u003e11\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eOrder now and join the 200,000+ people who trust ProHealth Sirtuin 6 Activator for their cellular health!\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eIngredients:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBrown Seaweed\u003c\/strong\u003e \u003cem\u003e(Fucus vesiculosus)\u003c\/em\u003e: A rich source of fucoidan, a bioactive polysaccharide recognized for supporting cellular health and activating SIRT6, the longevity enzyme.*\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eRahnasto-Rilla M et al. \u003cem\u003eMar Drugs.\u003c\/em\u003e 2017;15(6):190.\u003c\/li\u003e\n\u003cli\u003eKawaguchi T et al. \u003cem\u003eInt J Oncol\u003c\/em\u003e. 2015;46(5):2216-2222.\u003c\/li\u003e\n\u003cli\u003eYu W et al. Mol Nutr Food Res. 2017;61(10):1700136.\u003c\/li\u003e\n\u003cli\u003eCao L et al. \u003cem\u003eMar Drugs\u003c\/em\u003e. 2020;18(11):564.\u003c\/li\u003e\n\u003cli\u003eLi B et al. \u003cem\u003eMolecules\u003c\/em\u003e. 2008;13(8):1671-1695.\u003c\/li\u003e\n\u003cli\u003eLópez-Otín C et al. \u003cem\u003eCell\u003c\/em\u003e. 2023;186(2):243-278.\u003c\/li\u003e\n\u003cli\u003eIso H and Kubota Y. \u003cem\u003eAsian Pac J Cancer Prev\u003c\/em\u003e. 2007;8 Suppl:35-80.\u003c\/li\u003e\n\u003cli\u003eJayawardena TU et al. \u003cem\u003eMar Drugs\u003c\/em\u003e. 2022;20(12):755.\u003c\/li\u003e\n\u003cli\u003eApostolova E et al. \u003cem\u003ePolymers\u003c\/em\u003e. 2020;12(10):2338.\u003c\/li\u003e\n\u003cli\u003eBogolitsyn K et al. \u003cem\u003ePlant Foods Hum Nutr\u003c\/em\u003e. 2024;79(2):511-517.\u003c\/li\u003e\n\u003cli\u003eLuthuli S et al. \u003cem\u003eMar Drugs\u003c\/em\u003e. 2019;17(9):487.\u003c\/li\u003e\n\u003cli\u003eCatarino MD et al. \u003cem\u003eMar Drugs\u003c\/em\u003e. 2018;16(8):249.\u003c\/li\u003e\n\u003cli\u003eZhang L et al. \u003cem\u003eInnov Aging\u003c\/em\u003e. 2022;6(Suppl 1):130.\u003c\/li\u003e\n\u003cli\u003eMyers S et al. \u003cem\u003eBiol Targets Ther\u003c\/em\u003e. 2011;45.\u003c\/li\u003e\n\u003cli\u003eMyers S. \u003cem\u003eBiol Targets Ther\u003c\/em\u003e. 2010;33.\u003c\/li\u003e\n\u003cli\u003eLi X et al. \u003cem\u003eFront Cell Dev Biol\u003c\/em\u003e. 2021;9:641315.\u003c\/li\u003e\n\u003cli\u003eZhang N et al. \u003cem\u003eCell Cycle.\u003c\/em\u003e 2016;15(7):1009-1018.\u003c\/li\u003e\n\u003cli\u003eChilton WL et al. \u003cem\u003ePLoS ONE\u003c\/em\u003e. 2014;9(4):e92088.\u003c\/li\u003e\n\u003cli\u003eAkter R et al. \u003cem\u003eInt J Mol Sci\u003c\/em\u003e. 2021;22(8):4180.\u003c\/li\u003e\n\u003cli\u003eZhang L et al. \u003cem\u003eInnov Aging\u003c\/em\u003e. 2022;6(Suppl 1):130.\u003c\/li\u003e\n\u003cli\u003eGorbunova V. \u003cem\u003eInnov Aging\u003c\/em\u003e. 2019;3(Suppl 1):S8.\u003c\/li\u003e\n\u003cli\u003eKawamura A et al. \u003cem\u003eMar Drugs\u003c\/em\u003e. 2021;19(8):452.\u003c\/li\u003e\n\u003cli\u003eWillcox DC et al. \u003cem\u003eAnn NY Acad Sci\u003c\/em\u003e. 2009;1173:126-138.\u003c\/li\u003e\n\u003cli\u003eBuettner D. \u003cem\u003eNatl Geogr Books\u003c\/em\u003e. 2015.\u003c\/li\u003e\n\u003cli\u003eKorotkov A et al. \u003cem\u003eTrends Cell Biol\u003c\/em\u003e. 2021;31(12):994-1006.\u003c\/li\u003e\n\u003cli\u003eZhang L et al. \u003cem\u003eOxid Med Cell Longev\u003c\/em\u003e. 2019;2019:8918914.\u003c\/li\u003e\n\u003cli\u003eYang J et al. \u003cem\u003eInt J Biol Macromol.\u003c\/em\u003e 2024;277(Pt 3):134397.\u003c\/li\u003e\n\u003cli\u003eWang K et al. \u003cem\u003eTher Adv Chronic Dis\u003c\/em\u003e. 2022;13:20406223221076891.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable style=\"height: 243.333px;\" border=\"0\" cellpadding=\"0\" cellspacing=\"2\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 29.9667px;\"\u003e\n\u003cth align=\"left\" colspan=\"3\" style=\"font-size: 11pt; font-weight: bold; height: 29.9667px;\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 29.0333px;\"\u003e\n\u003ctd style=\"height: 29.0333px;\" colspan=\"3\" class=\"smalltext\"\u003eServing Size: 1 Capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 29.0333px;\"\u003e\n\u003ctd style=\"height: 29.0333px;\" colspan=\"3\" class=\"smalltext\"\u003eServings Per Container: 60\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 29.0333px;\"\u003e\n\u003ctd colspan=\"2\" class=\"smalltext\" style=\"font-weight: bold; height: 29.0333px;\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap; height: 29.0333px;\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 48.6333px;\"\u003e\n\u003ctd style=\"height: 48.6333px;\" class=\"smalltext\"\u003eFucoidan (from Bladderwrack [\u003cem\u003eFucus vesiculosus\u003c\/em\u003e] Whole Plant Extract and Brown Seaweed [\u003cem\u003eUndaria pinnatifida\u003c\/em\u003e] Whole Plant Extract)\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap; height: 48.6333px;\"\u003e400 mg\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap; height: 48.6333px;\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 48.6333px;\"\u003e\n\u003ctd style=\"height: 48.6333px;\" class=\"smalltext\"\u003eBladderwrack (\u003cem\u003eFucus vesiculosus\u003c\/em\u003e) Whole Plant Powder\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap; height: 48.6333px;\"\u003e100 mg\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap; height: 48.6333px;\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 29px;\"\u003e\n\u003ctd style=\"height: 29px;\" colspan=\"3\" class=\"smalltext\"\u003e† Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV.10.24\u003cbr\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eVegetable cellulose (capsule), microcrystalline cellulose, bamboo silica.\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMay contain\u003c\/strong\u003e traces of fish and\/or shellfish residue.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE: \u003c\/strong\u003eTake one (1) capsule daily, or as directed by your healthcare professional.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION: \u003c\/strong\u003eFor use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN.\u003c\/strong\u003e Store in a cool and dry place after opening.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Longevity","offers":[{"title":"Default Title","offer_id":51876124557678,"sku":"PH664","price":79.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH664_100CC_FRNT_600x600-Rev1024.png?v=1740435814"},{"product_id":"prohealth-rapid-reset-multi-senolytic-30-capsules-ph704","title":"Rapid Reset Multi-Senolytic - 30 capsules","description":"\u003cdiv class=\"product-benefits-copy\" style=\"text-align: left;\"\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eTotal-Body Reset: Powered by 15 Senolytic Compounds*\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHelps eliminate “zombie” senescent cells*\u003csup\u003e1-9 \u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003ePromotes youthful, high-functioning cells*\u003csup\u003e1-8,10\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eHelps maintain a healthy inflammatory response*\u003csup\u003e7,8,11-16 \u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eSupports total-body tissue rejuvenation*\u003csup\u003e7,12,17,18\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eStrategic 3-day protocol—modeled after leading senolytic research*\u003csup\u003e1,5,14,19\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH704_-_COA_Qalitex_LOT_23464_2025-08-25.pdf?v=1756406020\" rel=\"noopener noreferrer\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eA Broader, Deeper Cellular Cleanse*\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAs we age, “zombie” senescent cells accumulate throughout the body—releasing pro-inflammatory signals that impair cellular function, accelerate aging, and compromise tissue health. While individual compounds like quercetin and fisetin show individual promise, emerging research suggests that multi-senolytic strategies—combining multiple ingredients that act through complementary pathways—may offer a broader and more effective approach to clearing senescent cells across multiple tissues.*\u003csup\u003e1-9\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eRapid Reset Multi Senolytic delivers a powerful combination of 15 senolytic ingredients in a doctor-formulated 3-day protocol. Designed to activate the body’s natural clearance and renewal mechanisms, this high-intensity, low-frequency regimen is designed to spark the body’s natural senolytic mechanisms—promoting head-to-toe rejuvenation. Whether you're new to senolytics or upgrading your monthly longevity routine, this is ProHealth’s most comprehensive cellular reset yet.*\u003csup\u003e1-10,12,14-19\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eWhat Makes Ours Better?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMulti-Ingredient Strategy:\u003c\/strong\u003e Combines 15 carefully selected ingredients—each chosen for its unique senolytic potential—to target aging cells through complementary mechanisms.*\u003csup\u003e1-9,12,15-18\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUltra-Pure Sourcing:\u003c\/strong\u003e Uses high-quality, research-backed ingredients for purity, consistency, and results you can trust.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdvanced Absorption Technology:\u003c\/strong\u003e Features next-gen delivery systems like FenuMat® quercetin, liposomal resveratrol, and turmeric phytosome for enhanced bioavailability where it counts.*\u003csup\u003e20\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinically Researched Compounds:\u003c\/strong\u003e Includes well-studied senolytics like fisetin and quercetin, plus Senactiv®—a patented ingredient shown in human studies to reduce senescent cells in exercising skeletal muscle.*\u003csup\u003e1-9,12,15-18\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e3-Day Protocol:\u003c\/strong\u003e Built on the “hit-and-run” senolytic model, this short-duration strategy is designed to selectively clear senescent cells while minimizing effects on healthy tissue.*\u003csup\u003e1,5,14,19\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eThe ProHealth Difference\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDoctor-Formulated:\u003c\/strong\u003e Developed by our in-house science team in collaboration with leading wellness experts to address the root causes of aging.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTriple Lab Tested:\u003c\/strong\u003e Rigorously tested three times by independent third-party labs to guarantee unmatched potency and purity.\u003c\/li\u003e\n\u003cli\u003e \u003cstrong\u003eFull Transparency:\u003c\/strong\u003e In an industry full of misleading claims, we publish our third-party lab results—so you always know exactly what’s in every bottle. \u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eManufactured in the USA:\u003c\/strong\u003e Since 1988, we’ve proudly produced our supplements in FDA-regulated, GMP-certified facilities, ensuring the highest quality and safety standards.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e100-Day Risk-Free Guarantee:\u003c\/strong\u003e We stand behind our products. If you’re not completely satisfied, contact our Santa Barbara, CA office for a full refund—no hassle, no questions asked.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eThe Ultimate Weapon Against Zombie Cells*\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAs cells age or become damaged, they can enter a state called senescence—where they stop dividing but don’t die. Instead, they linger in the body as so-called “zombie cells,” releasing a mix of compounds known as SASP (Senescence-Associated Secretory Phenotype), which can influence surrounding cells and affect normal tissue function. Over time, senescent cells tend to build up in areas like the joints, skin, lungs, blood vessels, and fat tissue—contributing to many of the visible and invisible effects of aging.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eWhy Senolytics Matter\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSenolytics are a class of compounds that support the body’s ability to target and clear dysfunctional cells, promoting cellular balance and healthy tissue renewal.*\u003csup\u003e1-10\u003c\/sup\u003e However, there’s a challenge: \u003cstrong\u003enot all senescent cells are the same\u003c\/strong\u003e. These cells can vary in several ways:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eResistance to clearance\u003c\/li\u003e\n\u003cli\u003eLocation of accumulation in the body\u003c\/li\u003e\n\u003cli\u003eSignaling molecules they release\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eDue to this variability, while single-ingredient senolytics can offer targeted support, a multi-senolytic strategy is more effective. It casts a broader net, helping to address diverse senescent cell populations across multiple tissues and cell types.*\u003csup\u003e1-3,5-8,10\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eIntroducing: The 3-Day Rapid Reset Protocol\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis science-backed protocol uses short bursts of high-intensity senolytic activity—also known as a “hit-and-run” strategy—to help clear lingering senescent cells and support full-body cellular renewal.*\u003csup\u003e1-9,12,14,17,19,28\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow to Use: \u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTake ten (10) capsules daily for 3 consecutive days\u003c\/li\u003e\n\u003cli\u003eDiscontinue use on day 4\u003c\/li\u003e\n\u003cli\u003eWait 4–6 weeks before repeating the cycle\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThis intermittent approach is designed to deliver meaningful results in a compact timeframe—without the need for continuous supplementation.*\u003csup\u003e1,5,14,19\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eFor ongoing cellular support between senolytic cycles, daily antioxidant compounds like Quercetin or Fisetin can help maintain a healthy internal environment.*\u003csup\u003e1-7\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eA Word from our Chief Science Officer\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e“Clearing senescent cells is one of the most promising frontiers in longevity science. While single-agent protocols are a good starting point, aging is complex, and senescent cells behave differently depending on the tissue and the signals involved. That’s why our Rapid Reset Multi Senolytic takes a broader, more comprehensive approach, combining 15 potent compounds into an easy-to-follow 3-day protocol. This is a new benchmark in senolytic support.” \u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eIngredient Highlights\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSenactiv®\u003c\/strong\u003e: A proprietary blend of extracts from Panax notoginseng and Rosa roxburghii, clinically shown to help reduce senescent cells in muscle.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFisetin\u003c\/strong\u003e: A polyphenol found in fruits like strawberries and apples, shown in studies to be one of the most potent senolytic agents available today.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuercetin\u003c\/strong\u003e: Often combined with other compounds, this flavonoid has been studied for its role in promoting the removal of senescent cells and improving age-related conditions.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTrans-Resveratrol\u003c\/strong\u003e: A polyphenol commonly found in red grapes, known for activating longevity-associated sirtuins and supporting heart and brain health.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCurcuminoids\u003c\/strong\u003e: A group of yellow pigments extracted from turmeric root, commonly used to support a healthy inflammatory response.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCitrus Peel Blend\u003c\/strong\u003e: Powerful polyphenols derived from citrus fruits, recognized for supporting healthy blood vessels and combating free radicals.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePhycocyanin\u003c\/strong\u003e: A blue pigment derived from blue-green algae, valued for its antioxidant properties and ability to support cellular health.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTheaflavins\u003c\/strong\u003e: Unique polyphenols formed during the fermentation process of black tea, when catechins (the primary antioxidants in green tea) are converted into theaflavins.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEGCG\u003c\/strong\u003e: One of the most active and studied types of catechins in green tea, known for boosting metabolism and protecting cells from oxidative stress.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eApigenin\u003c\/strong\u003e: A flavonoid commonly found in parsley, chamomile, and celery, shown to target the CD38 enzyme and support healthy NAD+ levels.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRutin\u003c\/strong\u003e: A bioflavonoid related to quercetin, known for its strong antioxidant properties and its key role in supporting vascular health.*\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003ePioneering Health and Wellness Products Since 1988\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor nearly four decades, ProHealth has been dedicated to crafting the world's highest-quality supplements—rooted in innovation, integrity, and a passion for healthy aging. With a long-standing A+ rating from the Better Business Bureau, our reputation for purity and potency has made us one of the most trusted names in the industry. Our commitment to scientific rigor, premium sourcing, and results you can feel continues to drive everything we do.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003col\u003e\n\u003cli\u003eMahoney SA et al. \u003cem\u003eAging Cell\u003c\/em\u003e. 2024;23(3):e14060.\u003c\/li\u003e\n\u003cli\u003eYousefzadeh MJ et al. 2018;36:18-28.\u003c\/li\u003e\n\u003cli\u003eZhao R et al. \u003cem\u003ePeerJ\u003c\/em\u003e. 2023;11:e16463.\u003c\/li\u003e\n\u003cli\u003eDe Sousa Lages A et al. \u003cem\u003eInt J Mol Sci\u003c\/em\u003e. 2022;23(17):9957.\u003c\/li\u003e\n\u003cli\u003eLorenzo EC et al. \u003cem\u003eFront Aging\u003c\/em\u003e. 2023;4:1161799.\u003c\/li\u003e\n\u003cli\u003eTavenier J et al. \u003cem\u003eMech Ageing Dev\u003c\/em\u003e. 2024;222:111995.\u003c\/li\u003e\n\u003cli\u003eDeledda A et al. \u003cem\u003eInt J Mol Sci\u003c\/em\u003e. 2022;23(24):16219.\u003c\/li\u003e\n\u003cli\u003eWiciński M et al. \u003cem\u003eNutrients\u003c\/em\u003e. 2023;15(16):3578.\u003c\/li\u003e\n\u003cli\u003eZhu Y et al. \u003cem\u003eAging Cell\u003c\/em\u003e. 2015;14(4):644-658.\u003c\/li\u003e\n\u003cli\u003eZheng LT et al. \u003cem\u003eInt Immunopharmacol\u003c\/em\u003e. 2008;8(3):484-494.\u003c\/li\u003e\n\u003cli\u003eDias E, Poojary DD. 2024;6(3).\u003c\/li\u003e\n\u003cli\u003eMbara KC et al. \u003cem\u003ePharm Med\u003c\/em\u003e. 2022;36(6):331-352.\u003c\/li\u003e\n\u003cli\u003eKhan N et al. \u003cem\u003eAntioxid Redox Signal\u003c\/em\u003e. 2013;19(2):151-162.\u003c\/li\u003e\n\u003cli\u003eSun Y et al. \u003cem\u003eLife Med\u003c\/em\u003e. 2022;1(2):103-119.\u003c\/li\u003e\n\u003cli\u003eDella Vedova L et al. \u003cem\u003ePharmaceuticals\u003c\/em\u003e. 2025;18(2):138\u003c\/li\u003e\n\u003cli\u003ePirmoradi S et al. \u003cem\u003eDrug Res\u003c\/em\u003e. 2018;68(04):213-221.\u003c\/li\u003e\n\u003cli\u003eWu J et al. \u003cem\u003eJ Ginseng Res\u003c\/em\u003e. 2019;43(4):580-588.\u003c\/li\u003e\n\u003cli\u003eSohn EJ et al. \u003cem\u003eAm J Chin Med\u003c\/em\u003e. 2018;46(04):853-873.\u003c\/li\u003e\n\u003cli\u003eHickson LJ et al. \u003cem\u003eEBioMedicine\u003c\/em\u003e. 2019;47:446-456.\u003c\/li\u003e\n\u003cli\u003eJoseph A et al. \u003cem\u003eACS Omega\u003c\/em\u003e. 2022;7(50):46825-46832.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable style=\"height: 791.333px;\" width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 50.3333px;\"\u003e\n\u003cth colspan=\"3\" style=\"font-size: 11pt; font-weight: bold; height: 50.3333px; width: 99.297%;\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 49.4px;\"\u003e\n\u003ctd style=\"height: 49.4px; width: 99.297%;\" colspan=\"3\" class=\"smalltext\"\u003eServing Size: 10 Capsules\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 49.4px;\"\u003e\n\u003ctd style=\"height: 49.4px; width: 99.297%;\" colspan=\"3\" class=\"smalltext\"\u003eServings Per Container: 3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 49.4px;\"\u003e\n\u003ctd colspan=\"2\" class=\"smalltext\" style=\"font-weight: bold; height: 49.4px; width: 93.3216%;\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 5.9754%;\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 49.4px;\"\u003e\n\u003ctd style=\"height: 49.4px; width: 82.9525%;\" class=\"smalltext\"\u003eFisetin (from \u003cem\u003eRhus succedanea\u003c\/em\u003e Stem Extract)\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 10.3691%;\" align=\"right\"\u003e1,500 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 5.9754%;\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 49.4px;\"\u003e\n\u003ctd style=\"height: 49.4px; width: 82.9525%;\" class=\"smalltext\"\u003eFenumat® Quercetin Complex (from \u003cem\u003eSophora japonica\u003c\/em\u003e Flower Buds, Fenugreek Seeds, Sunflower Lecithin)\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 10.3691%;\" align=\"right\"\u003e1,000 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 5.9754%;\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 49.4px;\"\u003e\n\u003ctd style=\"height: 49.4px; width: 82.9525%;\" class=\"smalltext\"\u003eVeri-te® Trans-Resveratrol\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 10.3691%;\" align=\"right\"\u003e500 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 5.9754%;\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 49.4px;\"\u003e\n\u003ctd style=\"height: 49.4px; width: 82.9525%;\" class=\"smalltext\"\u003eMeriva® Turmeric Phytosome™ (\u003cem\u003eCurcuma longa\u003c\/em\u003e Root Extract\/Phospholipid Complex from Sunflower)\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 10.3691%;\" align=\"right\"\u003e500 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 5.9754%;\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 49.4px;\"\u003e\n\u003ctd style=\"height: 49.4px; width: 82.9525%;\" class=\"smalltext\"\u003e\n\u003cstrong\u003eCitrus Peel Blend\u003c\/strong\u003e\u003cbr\u003eHesperidin, Naringin, Tangeretin, Nobiletin\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 10.3691%;\" align=\"right\"\u003e400 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 5.9754%;\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 49.4px;\"\u003e\n\u003ctd style=\"height: 49.4px; width: 82.9525%;\" class=\"smalltext\"\u003ePhycocyanin (from Blue Spirulina (\u003cem\u003eArthrospira platensis\u003c\/em\u003e) Whole Algae Extract)\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 10.3691%;\" align=\"right\"\u003e300 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 5.9754%;\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 49.4px;\"\u003e\n\u003ctd style=\"height: 49.4px; width: 82.9525%;\" class=\"smalltext\"\u003eTheaflavins (from Black Tea Leaf Extract)\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 10.3691%;\" align=\"right\"\u003e275 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 5.9754%;\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 49.4px;\"\u003e\n\u003ctd style=\"height: 49.4px; width: 82.9525%;\" class=\"smalltext\"\u003eEGCG (from Green Tea Leaf Extract)\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 10.3691%;\" align=\"right\"\u003e200 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 5.9754%;\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 49.4px;\"\u003e\n\u003ctd style=\"height: 49.4px; width: 82.9525%;\" class=\"smalltext\"\u003eApigenin (from \u003cem\u003eApium graveolens\u003c\/em\u003e Seed Extract)\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 10.3691%;\" align=\"right\"\u003e150 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 5.9754%;\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 49.4px;\"\u003e\n\u003ctd style=\"height: 49.4px; width: 82.9525%;\" class=\"smalltext\"\u003eRutin (from \u003cem\u003eSophora japonica\u003c\/em\u003e Flower Buds)\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 10.3691%;\" align=\"right\"\u003e100 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 5.9754%;\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 49.4px;\"\u003e\n\u003ctd style=\"height: 49.4px; width: 82.9525%;\" class=\"smalltext\"\u003eSenactiv® (\u003cem\u003ePanax notoginseng\u003c\/em\u003e Root Extract, \u003cem\u003eRosa roxburghii\u003c\/em\u003e Fruit Extract)\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 10.3691%;\" align=\"right\"\u003e50 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 49.4px; width: 5.9754%;\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 49.4px;\"\u003e\n\u003ctd style=\"height: 49.4px; width: 99.297%;\" colspan=\"3\" class=\"smalltext\"\u003e† Daily Value (DV) not established.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eFenuMat® is a registered trademark of Akay USA, LLC, an Oterra company. Veri-te® is a registered trademark of the Lallemand group. Meriva® and Phytosome™ are trademarks owned by Indena S.p.A., Italy. Senactiv® is a registered trademark of NuLiv Science USA Inc.\u003c\/p\u003e\n\u003cp\u003eREV.05.25\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eCellulose (capsule), rice flour.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE: \u003c\/strong\u003eTake ten (10) capsules per day on 3 consecutive days. Wait 4 weeks before repeating. Use monthly for best results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION: \u003c\/strong\u003eFor use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e. Store in a cool and dry place after opening.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Longevity","offers":[{"title":"Default Title","offer_id":52369695506798,"sku":"PH704","price":69.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH704_175CC_FRNT_600x600-REV-0425.png?v=1756147590"},{"product_id":"prohealth-sirtuin-1-activator-60-capsules-ph665","title":"Sirtuin 1 Activator - 60 capsules","description":"\u003cdiv style=\"text-align: left;\" class=\"product-benefits-copy\"\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eSwitch On the Longevity Gene\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eActivates and supports SIRT1*\u003csup\u003e1-7\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003ePromotes healthy aging at the cellular level*\u003csup\u003e2,3,8-11\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eStrengthens the body’s antioxidant network*\u003csup\u003e12\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eHelps maintain metabolic and inflammatory health*\u003csup\u003e13\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eBoosts mitochondrial biogenesis and energy output*\u003csup\u003e1,3\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH665_-_COA_Brighton_LOT_26058_2025-11-11_2.pdf?v=1763393665\" rel=\"noopener noreferrer\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eThe Science of SIRT1 \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eInside every cell is a guardian protein called sirtuin 1 (SIRT1), short for Silent Information Regulator. It helps decide which parts of your DNA stay quiet and which stay active, helping cells adapt to stress, maintain energy efficiency, and resist the effects of aging.\u003c\/p\u003e\n\u003cp\u003eCommonly known as the \"longevity switch,\" SIRT1 is involved in DNA repair, the removal of damaged cellular components, and the optimization of energy use. As we age, SIRT1 activity naturally declines due to factors such as oxidative stress, poor diet, disrupted sleep, and environmental challenges. This reduction is linked to diminished cellular resilience and many of the classic signs of aging.\u003c\/p\u003e\n\u003cp\u003eThe good news is that certain food compounds can help support SIRT1 function. Plant-derived polyphenols such as resveratrol (from red grapes) and pterostilbene (from blueberries) are among the best-studied for their ability to activate SIRT1 and promote healthy cellular aging. These compounds mimic calorie restriction at the molecular level, helping to reactivate SIRT1 and restore youthful gene expression patterns. By boosting SIRT1 activity, they help shift cells into a protective, repair-focused state, supporting the body’s natural defenses as we age.*\u003csup\u003e1-7\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eWhy Resveratrol + Pterostilbene Work Better Together \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eResveratrol is well-known for supporting SIRT1, but the body clears it fast. The liver converts most of it into inactive metabolites within minutes. Blood levels fall quickly, so only a limited amount reaches cells. The effect on SIRT1 is meaningful, yet short-lived.*\u003csup\u003e1-3,5-7\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003ePterostilbene shifts the profile. It is a close relative of resveratrol with two methyl groups that improve its performance.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eUp to 4× higher oral bioavailability*\u003c\/li\u003e\n\u003cli\u003eGreater lipophilicity for superior cellular penetration*\u003c\/li\u003e\n\u003cli\u003eSignificantly longer half-life in the body (up to 7× longer than resveratrol)*\u003csup\u003e4,14-16\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eWhen used together in a balanced ratio, the two ingredients work in sequence. Resveratrol supports a fast SIRT1 response. Pterostilbene keeps that response active for a longer period due to its greater stability. This provides steadier sirtuin pathway support than resveratrol alone.*\u003csup\u003e1-7,14-16\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eWhat Makes Ours Better?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e4:1 Polyphenol Complex:\u003c\/strong\u003e Balanced to reflect bioavailability differences between resveratrol and pterostilbene.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinically Studied Forms:\u003c\/strong\u003e Includes the active trans form of resveratrol and pterostilbene for consistency and purity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLongevity Pathway Support:\u003c\/strong\u003e Engages SIRT1, AMPK and PGC-1α pathways linked to mitochondrial function and cellular upkeep.*\u003csup\u003e1-7\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMinimalist Formula:\u003c\/strong\u003e Uses only active polyphenols for a straightforward, clean profile.*\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eThe ProHealth Difference\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDoctor-Formulated:\u003c\/strong\u003e Developed by our in-house science team in collaboration with leading wellness experts.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTriple Lab Tested:\u003c\/strong\u003e Verified three times by independent labs for purity and potency.\u003c\/li\u003e\n\u003cli\u003e \u003cstrong\u003eFull Transparency:\u003c\/strong\u003e Third-party test results published online for complete confidence.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUSA Manufactured:\u003c\/strong\u003e Proudly manufactured in the USA in FDA-registered, GMP-certified facilities since 1988.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e100-Day Risk-Free Guarantee:\u003c\/strong\u003e If you’re not fully satisfied, we’ll refund your purchase in full.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eA Word from our Chief Science Officer\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\"Resveratrol brought SIRT1 into the spotlight, but bioavailability has always limited its potential. By combining it with pterostilbene, we’re matching kinetics with biology — ensuring both rapid activation and sustained support of this key longevity pathway.\"\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eIngredient Info\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTrans-Resveratrol:\u003c\/strong\u003e The active, naturally occurring form of resveratrol that supports key cellular pathways involved in healthy aging.*\u003cbr\u003e\u003cstrong\u003eTrans-Pterostilbene:\u003c\/strong\u003e A lipophilic stilbene that engages the SIRT1 pathway and complements resveratrol for steady cellular support.*\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eDella Vedova L et al. \u003cem\u003ePharmaceuticals (Basel)\u003c\/em\u003e. 2025;18(2):138.\u003c\/li\u003e\n\u003cli\u003eZhou DD et al. \u003cem\u003eSubcell Biochem\u003c\/em\u003e. 2024;107:183-203.\u003c\/li\u003e\n\u003cli\u003eLi YR et al. \u003cem\u003eBiofactors\u003c\/em\u003e. 2018;44(1):69-82.\u003c\/li\u003e\n\u003cli\u003eWood JG et al. \u003cem\u003eNature\u003c\/em\u003e. 2004;430(7000):686-689.\u003c\/li\u003e\n\u003cli\u003eKuršvietienė L et al. \u003cem\u003eMedicina\u003c\/em\u003e. 2016;52(3),148-155.\u003c\/li\u003e\n\u003cli\u003eLakshminarasimhan M et al. \u003cem\u003eAging (Albany NY)\u003c\/em\u003e. 2013;5(3),151.\u003c\/li\u003e\n\u003cli\u003eBorra MT et al. \u003cem\u003eJ Biol Chem\u003c\/em\u003e. 2005;280(17),17187-17195.\u003c\/li\u003e\n\u003cli\u003eThaung Zaw JJ et al. \u003cem\u003eClin Nutr\u003c\/em\u003e. 2021;40(3):820-829.\u003c\/li\u003e\n\u003cli\u003eThaung Zaw JJ et al. \u003cem\u003eMenopause.\u003c\/em\u003e 2021;28(1):40-49.\u003c\/li\u003e\n\u003cli\u003eWong RH et al. \u003cem\u003eJ Bone Miner Res\u003c\/em\u003e. 2020;35(11):2121-2131.\u003c\/li\u003e\n\u003cli\u003eThaung Zaw JJ et al. \u003cem\u003eNutrients\u003c\/em\u003e. 2020;12(3):828.\u003c\/li\u003e\n\u003cli\u003eChan EWC et al. \u003cem\u003eJ Appl Pharm Sci.\u003c\/em\u003e 2019;9(7):124-129.\u003c\/li\u003e\n\u003cli\u003eDella Vedova L et a. \u003cem\u003ePharmaceuticals (Basel)\u003c\/em\u003e. 2025;18(2):138.\u003c\/li\u003e\n\u003cli\u003eWang P, Sang S. \u003cem\u003eBiofactors.\u003c\/em\u003e 2018;44(1):16-25.\u003c\/li\u003e\n\u003cli\u003eRiche DM et al.  \u003cem\u003eJ Toxicol\u003c\/em\u003e. 2013;2013:463595.\u003c\/li\u003e\n\u003cli\u003eKapetanovic IM et al. \u003cem\u003eCancer Chemother Pharmacol.\u003c\/em\u003e 2011;68(3):593-601.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable border=\"0\" cellpadding=\"0\" cellspacing=\"2\" width=\"100%\" style=\"height: 275.333px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 20.5333px;\"\u003e\n\u003cth align=\"left\" style=\"font-size: 11pt; font-weight: bold; height: 20.5333px;\" colspan=\"3\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\" style=\"height: 19.6px;\"\u003eServing Size: 1 Capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\" style=\"height: 19.6px;\"\u003eServings Per Container: 60\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd style=\"font-weight: bold; height: 19.6px;\" class=\"smalltext\" colspan=\"2\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap; height: 19.6px;\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19.6px;\"\u003eVeri-te® Trans-Resveratrol\u003c\/td\u003e\n\u003ctd align=\"right\" style=\"white-space: nowrap; height: 19.6px;\" class=\"smalltext\"\u003e200 mg\u003c\/td\u003e\n\u003ctd align=\"right\" style=\"white-space: nowrap; height: 19.6px;\" class=\"smalltext\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19.6px;\"\u003eTrans-Pterostilbene\u003c\/td\u003e\n\u003ctd align=\"right\" style=\"white-space: nowrap; height: 19.6px;\" class=\"smalltext\"\u003e50 mg\u003c\/td\u003e\n\u003ctd align=\"right\" style=\"white-space: nowrap; height: 19.6px;\" class=\"smalltext\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.2px;\"\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\" style=\"height: 39.2px;\"\u003e† Percent Daily Values (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cbr\u003e\n\u003cp\u003eREV.10.25\u003c\/p\u003e\nVeri-te® is a registered trademark of the Lallemand group.\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eRice flour, hypromellose (capsule).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE: \u003c\/strong\u003eTake one (1) capsule per day with food.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION: \u003c\/strong\u003eFor use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e. Store in a cool and dry place after opening.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Longevity","offers":[{"title":"Default Title","offer_id":53009796727150,"sku":"PH665","price":39.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH665_175CC_FRNT_600x600-REV-1025.png?v=1763679436"}],"url":"https:\/\/www.prohealth.com\/collections\/save-30-on-sirtuin-activating-supplements.oembed","provider":"ProHealth.com","version":"1.0","type":"link"}