{"title":"Upcoming Discontinued Products","description":"","products":[{"product_id":"prohealth-optimized-curcumin-body-and-joint-60-capsules-ph408","title":"Optimized Curcumin for Body and Joint - 60 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003ch2\u003eBreakthrough Bioavailable Supplement that Supports Joint Health and Overall Wellbeing*\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports a healthy inflammation response*\u003c\/li\u003e\n\u003cli\u003eSupports joint health and flexibility*\u003c\/li\u003e\n\u003cli\u003ePasses the blood-brain barrier\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca style=\"color: #0000ff;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH408_-_COA_Brighton__LOT_T572A_2.pdf?v=1741822287\" target=\"_blank\"\u003eView Certificate of Analysis »\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable style=\"width: 100%;\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth style=\"font-size: 11pt; font-weight: bold;\" colspan=\"3\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003eServing Size: 2 Capsules\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003eServings Per Container: 30\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" style=\"font-weight: bold;\" colspan=\"2\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eWokVel® \u003cem\u003e(Boswellia Serrata)\u003c\/em\u003e (gum resin)  \u003cbr\u003e\n\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e666 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eLONGVIDA® Optimized Curcumin® Extract (from \u003cem\u003eCurcuma longa\u003c\/em\u003e root)\u003cbr\u003e\n\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e400 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003e† Daily Value not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV.10.23 \u003cbr\u003e\u003cbr\u003e Longvida® Optimized Curcumin® and WokVel® are registered trademarks of Verdure Sciences, Inc. \u003cbr\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eGround rice hull, vegetable capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCONTAINS: \u003c\/strong\u003eSoy (as soy lecithin, a component of Longvida®)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDOES NOT CONTAIN: \u003c\/strong\u003eDairy, egg, wheat, gluten, corn, fish, shellfish, tree nuts, peanuts.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE: \u003c\/strong\u003eTake 2 capsules per day, or as recommended by your healthcare professional.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION: \u003c\/strong\u003eDo not take turmeric if you have a biliary tract obstruction or are taking a steroidal anti-inflammatory such as prednisone. Not intended for use by pregnant or nursing women. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your healthcare professional before using this product.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNOTE:\u003c\/strong\u003e Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken. KEEP OUT OF REACH OF CHILDREN\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-how-it-work-copy\"\u003e\n\u003cp\u003eThis unique formula combines two clinically studied ingredients to bring you a powerful supplement to support a healthy inflammatory response and enhance joint health.*\u003c\/p\u003e\n\u003cp\u003eProHealth has combined the widely studied Longvida® Curcumin with the most bioavailable form of Boswellia to create a product that targets the specific needs of our customers. Optimized Curcumin Longvida® is a proprietary compound that contains the natural antioxidant curcumin to provide maximum absorption into the body. Longvida® has been studied and tested to support joint, cognitive, and overall health.*\u003c\/p\u003e\n\u003ch2\u003eSo What Makes Longvida® Unique?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eMore than a dozen research studies and clinical trials in independent labs have been completed on Longvida.(1)\u003c\/li\u003e\n\u003cli\u003eOne small, single daily dose of Longvida offered significant health benefits in just 30 days.\u003c\/li\u003e\n\u003cli\u003ePublished chronic-dosing safety studies on Longvida support a strong safety profile.\u003c\/li\u003e\n\u003cli\u003eLongvida is 285\u003cstrong\u003e times more bioavailable\u003c\/strong\u003e than regular curcumin.\u003c\/li\u003e\n\u003cli\u003eLongvida offers therapeutic levels of free (not deactivated\/metabolized) curcumin.\u003c\/li\u003e\n\u003cli\u003eCurcumin from Longvida passes the blood-brain barrier.\u003c\/li\u003e\n\u003cli\u003eLongvida contains no metabolic inhibitors, volatile oils, or crude, unpurified ingredients.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cbr\u003e\n\u003ch2\u003eAbout Wokvel-Bioavailable Boswellia\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eWokvel® Extract is a clinically researched botanical ingredient that supports joint health and flexibility.*\u003c\/li\u003e\n\u003cli\u003eDerived from Boswellia serrata, Wokvel® Extract is an all-natural, science-backed ingredient for premium dietary supplements that promote joint health.\u003c\/li\u003e\n\u003cli\u003eStandardized to the natural-spectrum fingerprint of boswellic acids, Wokvel® is one of the only joint health ingredients shown to be bioavailable in human trials.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan style=\"color: #666666; font-size: 8pt;\"\u003e*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.\u003c\/span\u003e\n\u003c\/div\u003e","brand":"ProHealth Longevity","offers":[{"title":"Default Title","offer_id":24232444100708,"sku":"PH408","price":10.2,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH408_175ML_FRNT_600x600_f75dd1a1-ba6a-4422-a15c-2233759bff52.png?v=1737672829"},{"product_id":"prohealth-olive-leaf-extract-15-oleuropein-500-mg-60-capsules-ph123","title":"Olive Leaf Extract - 15% Oleuropein - 500 mg, 60 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003ch2\u003eSupports heart health and encourages a healthy inflammatory response.\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports healthy heart function\u003c\/li\u003e\n\u003cli\u003eAntioxidant that may help support normal lipid balance\u003c\/li\u003e\n\u003cli\u003eProtects against bacterial, viral, and yeast overgrowth\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH123_-_COA_TAL_LOT_23340_2025-08-13.pdf?v=1755552154\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis »\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eResearch-Supported Benefits:\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003ePromotes Healthy Immune Response:\u003c\/strong\u003e Oleuropein, one of the primary bioactive compounds in olive leaves and olive oil, is responsible for making the olive tree resistant to pathogens. When used as a supplement, it has been shown to have a similar effect on our immune system. By helping the body’s immune system to adapt to triggers, it helps reduce the overall inflammatory burden seen in aging broadly described as inflammaging.(1)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Heart Health:\u003c\/strong\u003e Oleuropein has shown to have numerous positive effects on heart health including supporting blood pressure, circulation and improving blood markers of heart health.(2-5)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAnti-Inflammatory Properties:\u003c\/strong\u003e The active ingredient in Olive Leaf Extract, oleuropein, has shown to have strong anti-inflammatory properties which can reduce oxidative stress, a leading driver of aging and chronic health concerns.(3)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Healthy Blood Sugar Management:\u003c\/strong\u003e Managing glucose (blood sugar) levels becomes more difficult as we get older even with a healthy diet. Oleuropein has shown to help maintain healthy blood sugar levels.(6)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Pojero F, Aiello A, Gervasi F, et al. Effects of oleuropein and hydroxytyrosol on inflammatory mediators: consequences on inflammaging. International Journal of Molecular Sciences. 2023;24(1):380. doi:10.3390\/ijms24010380 \u003cbr\u003e\u003cbr\u003e 2. Sharifi-Rad J, Rodrigues CF, Sharopov F, et al. Diet, lifestyle and cardiovascular diseases: linking pathophysiology to cardioprotective effects of natural bioactive compounds. International Journal of Environmental Research and Public Health. 2020;17(7):2326. doi:10.3390\/ijerph17072326 \u003cbr\u003e\u003cbr\u003e 3. Barbaro B, Toietta G, Maggio R, et al. Effects of the olive-derived polyphenol oleuropein on human health. International Journal of Molecular Sciences. 2014;15(10):18508-18524. doi:10.3390\/ijms151018508 \u003cbr\u003e\u003cbr\u003e 4. Andreadou I, Iliodromitis EK, Mikros E, et al. The olive constituent oleuropein exhibits anti-ischemic, antioxidative, and hypolipidemic effects in anesthetized rabbits ,. The Journal of Nutrition. 2006;136(8):2213-2219. doi:10.1093\/jn\/136.8.2213 \u003cbr\u003e\u003cbr\u003e 5. Janahmadi Z, Nekooeian AA, Moaref AR, Emamghoreishi M. Oleuropein offers cardioprotection in rats with acute myocardial infarction. Cardiovasc Toxicol. 2015;15(1):61-68. doi:10.1007\/s12012-014-9271-1 \u003cbr\u003e\u003cbr\u003e 6. Annunziata G. Oleuropein as a novel anti-diabetic nutraceutical. An overview. ADO. 2018;1(3). doi:10.32474\/ADO.2018.01.000113 \u003cbr\u003e\u003cbr\u003e 7. Huguet-Casquero A, Xu Y, Gainza E, Pedraz JL, Beloqui A. Oral delivery of oleuropein-loaded lipid nanocarriers alleviates inflammation and oxidative stress in acute colitis. International Journal of Pharmaceutics. 2020;586:119515. doi:10.1016\/j.ijpharm.2020.119515 \u003cbr\u003e\u003cbr\u003e 8. Lo Vasco VR, Leopizzi M, Di Maio V, et al. LPS, Oleuropein and Blueberry extracts affect the survival, morphology and Phosphoinositide signalling in stimulated human endothelial cells. J Cell Commun Signal. 2017;11(4):317-327. doi:10.1007\/s12079-017-0391-9 \u003cbr\u003e\u003cbr\u003e 9. Magrone T, Spagnoletta A, Salvatore R, et al. Olive Leaf Extracts Act as Modulators of the Human Immune Response. Endocr Metab Immune Disord Drug Targets. 2018;18(1):85-93. doi:10.2174\/1871530317666171116110537 \u003cbr\u003e\u003cbr\u003e 10. Ismail MA, Norhayati MN, Mohamad N. Olive leaf extract effect on cardiometabolic profile among adults with prehypertension and hypertension: a systematic review and meta-analysis. PeerJ. 2021;9:e11173. Published 2021 Apr 7. doi:10.7717\/peerj.11173 \u003cbr\u003e\u003cbr\u003e 11. Silvan JM, Guerrero-Hurtado E, Gutiérrez-Docio A, Alarcón-Cavero T, Prodanov M, Martinez-Rodriguez AJ. Olive-Leaf Extracts Modulate Inflammation and Oxidative Stress Associated with Human H. pylori Infection. Antioxidants (Basel). 2021;10(12):2030. Published 2021 Dec 20. doi:10.3390\/antiox10122030\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable style=\"width: 100%;\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth style=\"font-size: 11pt; font-weight: bold;\" colspan=\"3\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003eServing Size: 1 Capsule\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003eServings Per Container: 60\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" style=\"font-weight: bold;\" colspan=\"2\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eOlive Leaf Extract (standardized to contain 15% oleuropein) (\u003cem\u003eOleo europaea\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e500 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e\u003cspan\u003e†\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003e\n\u003cspan data-mce-fragment=\"1\"\u003e†\u003c\/span\u003eDaily Value not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nRev. 12.23 \n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eVegetable capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDOES NOT CONTAIN:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eDairy, egg, soy, wheat, gluten, corn, fish, shellfish, tree nuts, peanuts.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e take 1 capsule with food as needed, or as recommended\u003cbr data-mce-fragment=\"1\"\u003eby your healthcare professional.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e Not intended for use if you are pregnant or nursing. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your healthcare professional before using this product.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNOTE:\u003c\/strong\u003e\u003cspan\u003e Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken. Due to the natural color variations of olive leaves, product color will vary.\u003cstrong\u003e \u003c\/strong\u003e\u003c\/span\u003e\u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-how-it-work-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003eThe active ingredient in olive leaf capsule extract is called oleuropein. Oleuropein is a polyphenolic fraction derived from the fruit, leaves, bark and roots of the olive tree, which help make it strongly resistant to damage from insects and other factors.\u003c\/li\u003e\n\u003cli\u003eOleuropein is a chemical agent called elenolic acid, which has been shown to assist the body's immune defense.\u003c\/li\u003e\n\u003cli\u003eResearch studies have found that elenolic acid helps the body to balance levels of friendly bacteria and support the immune system. The energy-boosting benefits of olive leaf extract are believed to be the result of its ability to help fend off fungi, which overtax the immune system, and yeast overgrowth, which cause fatigue. The olive leaf capsule contains extract that provides nutritional support for detoxification at the cellular level, when the body is under stress.\u003c\/li\u003e\n\u003cli\u003eIt has been shown to protect RNA structure. Oleuropein imparts some important antioxidant benefits that may help reduce the build-up of LDL “bad” cholesterol and support healthy heart function.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"summary-copy\"\u003e\n\u003cp\u003e\u003cstrong\u003eHighly Concentrated Dose.\u003c\/strong\u003e Our olive leaf extract contains 500 mg per 1 capsule and is standardized to contain 15% oleuropein.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"ProHealth Longevity","offers":[{"title":"Default Title","offer_id":31777729183844,"sku":"PH123","price":12.49,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH123_175ML_FRNT_600x600_6e7aaf5c-224b-4eef-8924-de60a98010b1.png?v=1737588473"},{"product_id":"prohealth-enzogenol-pine-bark-extract-250-mg-60-capsules-ph624","title":"Enzogenol® Pine Bark Extract - 250 mg per serving, 60 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003ch2\u003eEnzogenol Pine Bark Extract is a powerful antioxidant which promotes longevity and overall wellness, especially for those over 40.\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003ePromotes cardiovascular health\u003c\/li\u003e\n\u003cli\u003eSupports cognitive function and brain plasticity\u003c\/li\u003e\n\u003cli\u003eImproves skin health and appearance\u003c\/li\u003e\n\u003cli\u003eProtects joints from wear and tear\u003c\/li\u003e\n\u003cli\u003eEnhances immunity and athletic recovery\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH624_-_COA_Brighton_LOT_26009_2025.08.13.pdf?v=1759941249\" rel=\"noopener noreferrer\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eResearch-Supported Benefits:\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003ePromotes Cardiovascular Health.\u003c\/strong\u003e Pine bark extract contains antioxidants, such as proanthocyanidins, that may contribute to maintaining heart health in older adults by improving blood flow and increasing plasma antioxidant capacity. In addition, its polyphenol content has been shown to modulate LDL cholesterol levels in human studies. (1)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Cognitive Function and Brain Plasticity.\u003c\/strong\u003ePine bark extract has been shown to promote autophagy, an internal process that removes dysfunctional cells, which may be beneficial for brain function and plasticity by maintaining neuron health and facilitating the formation of new neural connections. (2)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImproves Skin Health and Appearance.\u003c\/strong\u003e Pine bark extract is rich in proanthocyanins, compounds that may support collagen production and improve skin health by protecting against UV damage, promoting skin elasticity, and reducing the appearance of age-related skin issues. (3)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProtects Joints from Wear and Tear. \u003c\/strong\u003e The antioxidants in pine bark extract may help reduce joint discomfort and protect joints from age-related damage by neutralizing free radicals that cause oxidative stress and contribute to the breakdown of cartilage. (4,5)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImproves DNA Integrity.\u003c\/strong\u003e Pine bark extract supports DNA damage reduction as shown in a 12-week study of human subjects via enhanced capacity to control free radical damage in cells. (3, 6)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMay Improve Athletic Performance and Recovery.\u003c\/strong\u003e Some research suggests that pine bark extract could enhance cellular antioxidant levels, possibly promoting better athletic performance and recovery by reducing muscle fatigue and supporting muscle repair processes. (7)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Nakayama S, Kishimoto Y, Saita E, et al. Pine bark extract prevents low-density lipoprotein oxidation and regulates monocytic expression of antioxidant enzymes. Nutrition Research. 2015;35(1):56-64. doi:10.1016\/j.nutres.2014.10.010 \u003cbr\u003e\u003cbr\u003e2. Theadom A, Mahon S, Barker-Collo S, et al. Enzogenol for cognitive functioning in traumatic brain injury: a pilot placebo-controlled RCT. Eur J Neurol. 2013;20(8):1135-1144. doi:10.1111\/ene.12099 \u003cbr\u003e\u003cbr\u003e3. Senthilmohan ST, Zhang J, Stanley RA. Effects of flavonoid extract Enzogenol® with vitamin C on protein oxidation and DNA damage in older human subjects. Nutrition Research. 2003;23(9):1199-1210. doi:10.1016\/S0271-5317(03)00127-1 \u003cbr\u003e\u003cbr\u003e4. Yazaki Y. Utilization of flavonoid compounds from bark and wood: a review. Natural Product Communications. 2015;10(3):1934578X1501000. doi:10.1177\/1934578X1501000333 \u003cbr\u003e\u003cbr\u003e5. Li YY, Feng J, Zhang XL, Cui YY. Pine bark extracts: nutraceutical, pharmacological, and toxicological evaluation. J Pharmacol Exp Ther. 2015;353(1):9-16. doi:10.1124\/jpet.114.220277 \u003cbr\u003e\u003cbr\u003e6. Kim DS, Kim MS, Kang SW, Sung HY, Kang YH. Pine bark extract enzogenol attenuated tumor necrosis factor-α-induced endothelial cell adhesion and monocyte transmigration. J Agric Food Chem. 2010;58(11):7088-7095. doi:10.1021\/jf1005287 \u003cbr\u003e\u003cbr\u003e7. O’Callaghan YC, Drummond E, O’Gorman DM, O’Brien NM. Antioxidant and pro-apoptotic effects of marine-derived, multi-mineral aquamin supplemented with a pine bark extract, enzogenol, and a green tea extract, sunphenon. Journal of Medicinal Food. 2013;16(10):920-926. doi:10.1089\/jmf.2012.0258 \u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-how-it-work-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003eEnzogenol® Pine Bark Extract contains proanthocyanins, compounds that provide various health benefits, such as supporting cardiovascular health, brain function and skin health by promoting healthy blood flow, neuronal activity and collagen production, respectively. (5, 6, 8)\u003c\/li\u003e\n\u003cli\u003eThese compounds also play a role in maintaining cellular energy production and function, potentially supporting immunity and overall wellness by enhancing mitochondrial activity and reducing oxidative stress. (8)\u003c\/li\u003e\n\u003cli\u003ePine bark extract has been shown to exhibit positive effects on inflammatory pathways and support a healthy immune system. Research suggests that the proanthocyanins in pine bark extract can inhibit the production of pro-inflammatory cytokines and the activation of nuclear factor-kappa B (NF-κB), a protein complex that plays a central role in regulating the immune response to infection and inflammation. (7, 8)\u003c\/li\u003e\n\u003cli\u003eEnzogenol® Pine Bark Extract may enhance athletic performance and recovery by reducing exercise-induced oxidative stress. The potent antioxidant properties of the proanthocyanins found in pine bark extract can help neutralize free radicals generated during intense physical activity, protecting cells from damage and promoting faster recovery. Additionally, pine bark extract has been shown to improve blood flow and oxygen delivery to muscles, which can support endurance and overall performance. Research suggests that supplementation with pine bark extract may lead to reduced muscle soreness and faster recovery times, enabling athletes to maintain a consistent training regimen with less downtime. (4, 5, 6)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable border=\"0\" cellpadding=\"0\" cellspacing=\"2\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth align=\"left\" style=\"font-size: 11pt; font-weight: bold;\" colspan=\"3\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003eServing Size: 2 Capsules\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003eServings Per Container: 30\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold;\" class=\"smalltext\" colspan=\"2\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap;\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eEnzogenol® Pine Bark Extract \u003cem\u003e(Pinus radiata)\u003c\/em\u003e\n\u003c\/td\u003e\n\u003ctd align=\"right\" style=\"white-space: nowrap;\" class=\"smalltext\"\u003e250 mg\u003c\/td\u003e\n\u003ctd align=\"right\" style=\"white-space: nowrap;\" class=\"smalltext\"\u003e†\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003e† Daily value not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV.03.24\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eOrganic rice our, vegetable capsule.\u003cstrong\u003e \u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDOES NOT CONTAIN:\u003c\/strong\u003e Dairy, egg, soy, wheat, gluten, peanuts, tree nuts, fish, shellfish, sesame.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e Take 2 capsules per day, or as directed by your healthcare professional.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e Not intended for use by pregnant or nursing women. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your healthcare professional before using this product.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNOTE:\u003c\/strong\u003e Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"summary-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBetter Absorption.\u003c\/strong\u003e Our Enzogenol® Pine Bark Extract is formulated for optimal absorption, ensuring you receive the full benefits of this natural supplement by maximizing the bioavailability of its active compounds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigher Diversity of Compounds:\u003c\/strong\u003e Our Enzogenol® Pine Bark Extract, thanks to its mechanical fractionation process, offers a wider range of beneficial compounds. This higher diversity contributes to its enhanced antioxidant activity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigher Concentrations.\u003c\/strong\u003e Our Enzogenol® Pine Bark Extract is standardized at a higher concentration than other pine bark extracts available, so you get the benefits of more active compounds while taking a smaller dose.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch-Supported.\u003c\/strong\u003e Enzogenol® Pine Bark Extract is supported by numerous peer-reviewed, double-blind, placebo-controlled studies in humans, indicating its potential to promote longevity, heart health, and overall wellness in older adults.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Longevity","offers":[{"title":"Default Title","offer_id":41899501813860,"sku":"PH624","price":49.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH624_175ML_FRNT_600x600_b6f68dbc-b3b4-4da9-8329-198210b7ec5a.png?v=1738106254"},{"product_id":"prohealth-vitamin-b-12-5000-mcg-30-lozenges-ph639","title":"Vitamin B-12 - 5000 mcg, 30 lozenges","description":"\u003cdetails\u003e\n\u003ch2\u003eBenefits:\u003c\/h2\u003e\n\u003cp\u003eIntroducing ProHealth Longevity's Vitamin B12, a unique combination crafted to harness the synergistic benefits of multiple forms of Vitamin B12. This innovative formula incorporates methylcobalamin, dibencozide, cyanocobalamin, and hydroxycobalamin, each selected for their unique contributions to cellular health, energy metabolism, and overall longevity. While many B12 supplements focus solely on one form of B12, ProHealth Longevity's Vitamin B12 embraces a comprehensive approach, recognizing the diverse roles and benefits offered by each variant. From supporting brain function to enhancing energy levels and combating age-related declines, our formula is designed to optimize B12 status and promote vitality at every stage of life.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePlays a crucial role in maintaining cellular integrity by aiding in DNA synthesis and repair\u003c\/li\u003e\n\u003cli\u003eActs as a cofactor in the conversion of carbohydrates, fats, and proteins into usable energy\u003c\/li\u003e\n\u003cli\u003eSupports healthy brain aging by aiding in the regeneration of myelin, the protective sheath around nerve fibers\u003c\/li\u003e\n\u003cli\u003eProvides mood support by serving as a cofactor in the synthesis of neurotransmitters\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca style=\"color: #0000ff;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH639_-_COA_Brighton_LOT_26112_2026.02.06.pdf?v=1770304552\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eResearch-Supported Benefits:\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eEnhances cellular health.\u003c\/strong\u003e Vitamin B12 is a pivotal player in the synthesis and repair of DNA, critical processes that safeguard cellular integrity. Research has linked Vitamin B12 deficiency to disruptions in DNA synthesis and repair mechanisms, underscoring its importance in maintaining genetic stability. (1) Vitamin B12 offers further cellular protection by supporting telomere maintenance, the protective caps at the ends of chromosomes. Telomeres play a vital role in preserving DNA integrity during cell division, and their maintenance is closely linked to longevity and overall health. By supporting telomere integrity and DNA repair mechanisms, Vitamin B12 contributes to enhanced cellular resilience and longevity, offering comprehensive support for optimal aging.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHeathy heart aging:\u003c\/strong\u003e Vitamin B12 aids in the reduction of homocysteine levels, an amino acid implicated in various forms of DNA damage, including DNA strand breaks. Elevated homocysteine is associated with accelerated cardiovascular aging and increased risk of cardiovascular events. (2) Research shows that increasing vitamin B12 intake may reduce homocysteine levels up to 7%. (3)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePromotes energy production.\u003c\/strong\u003e Vitamin B12 is indispensable for sustaining energy levels, with its deficiency linked to reduced energy production in the body. Through its involvement in synthesizing SAMe, a vital methyl donor nutrient, Vitamin B12 supports mitochondrial function and the generation of ATP, the primary energy currency of cells. As we age, ATP production tends to decline, exacerbated by decreasing levels of Vitamin B12. This decline can lead to age-related fatigue and diminished stamina. Supplementation with Vitamin B12 may offer a solution by replenishing stores and potentially mitigating the decline in ATP production associated with aging.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePromotes Cognitive Health.\u003c\/strong\u003e Vitamin B12 plays a crucial role in maintaining cognitive function, and its deficiency is strongly associated with cognitive decline and memory impairment. (4) Its diverse functions in methylation, neurotransmitter synthesis, and mitochondrial activity are essential for optimal brain health. Notably, Vitamin B12 shows promise in mitigating age-related neurodegeneration by regulating inflammatory processes and protecting against the formation of amyloid beta (Aβ) plaque. (5) Supplementation with Vitamin B12 has potential to alleviate symptoms linked to accelerated brain aging and support overall cognitive well-being.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Mood.\u003c\/strong\u003e Vitamin B12 plays a vital role in the synthesis of essential mood-regulating neurotransmitters, including serotonin and dopamine. Serotonin, known as the \"feel-good\" neurotransmitter, is synthesized from the amino acid tryptophan in a process facilitated by SAMe, which in turn relies on sufficient levels of Vitamin B12 for optimal function. Similarly, dopamine, a neurotransmitter linked to reward, pleasure, and motivation, also depends on Vitamin B12 for its synthesis. Scientific studies have demonstrated that deficiency in Vitamin B12 correlates with mood dysregulation, contributing to symptoms such as irritability and personality changes. (6)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Alzoubi KH, Bayraktar E, Khabour O, Al-Azzam SI. Vitamin B12 protects against DNA damage induced by hydrochlorothiazide. Saudi Pharm J. 2018;26(6):786-789. doi:10.1016\/j.jsps.2018.04.005 \u003cbr\u003e\u003cbr\u003e2. Yan Y, Yin Y, Feng X, et al. Homocysteine aggravates DNA damage by impairing the FA\/Brca1 Pathway in NE4C murine neural stem cells. Int J Med Sci. 2020;17(16):2477-2486. Published 2020 Sep 9. doi:10.7150\/ijms.49246 \u003cbr\u003e\u003cbr\u003e3. Maruyama K, S Eshak E, Kinuta M, et al. Association between vitamin B group supplementation with changes in % flow-mediated dilatation and plasma homocysteine levels: a randomized controlled trial. J Clin Biochem Nutr. 2019;64(3):243-249. doi:10.3164\/jcbn.17-56 \u003cbr\u003e\u003cbr\u003e4. Jatoi S, Hafeez A, Riaz SU, Ali A, Ghauri MI, Zehra M. Low Vitamin B12 Levels: An Underestimated Cause Of Minimal Cognitive Impairment And Dementia. Cureus. 2020;12(2):e6976. Published 2020 Feb 13. doi:10.7759\/cureus.6976 \u003cbr\u003e\u003cbr\u003e5. Lam AB, Kervin K, Tanis JE. Vitamin B12 impacts amyloid beta-induced proteotoxicity by regulating the methionine\/S-adenosylmethionine cycle. Cell Rep. 2021;36(13):109753. doi:10.1016\/j.celrep.2021.109753 \u003cbr\u003e\u003cbr\u003e6. Sangle P, Sandhu O, Aftab Z, Anthony AT, Khan S. Vitamin B12 Supplementation: Preventing Onset and Improving Prognosis of Depre**ion. Cureus. 2020;12(10):e11169. Published 2020 Oct 26. doi:10.7759\/cureus.11169\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cfooter\u003e\n\u003cul\u003e\n\u003cli\u003eWhen taken as a supplement, Vitamin B12 is released in the stomach and binds to intrinsic factor, a protein produced by the stomach lining.\u003c\/li\u003e\n\u003cli\u003eThe Vitamin B12-intrinsic factor complex travels to the small intestine, where it is absorbed into the bloodstream through specialized receptors in the intestinal lining.\u003c\/li\u003e\n\u003cli\u003eOnce in the bloodstream, Vitamin B12 is transported to various tissues and cells throughout the body, where it exerts its functions.\u003c\/li\u003e\n\u003cli\u003eVitamin B12 plays a crucial role in energy metabolism as a cofactor for the enzyme methionine synthase, which helps convert homocysteine to methionine. Methionine serves as a precursor for S-adenosylmethionine (SAMe), a key methyl donor in cellular reactions.\u003c\/li\u003e\n\u003cli\u003eSAMe participates in methylation reactions essential for ATP synthesis, the primary energy currency of cells, thus contributing to overall energy production and vitality.\u003c\/li\u003e\n\u003cli\u003eVitamin B12 helps maintain mitochondrial health and facilitates neurotransmitter synthesis, promoting youthful cognitive functioning and reducing the risk of age-related cognitive decline.\u003c\/li\u003e\n\u003cli\u003eVitamin B12 is crucial for brain health and cognitive function, as it supports mitochondrial function and neurotransmitter synthesis. Mitochondria in brain cells require Vitamin B12 for energy production, which is essential for maintaining neuronal activity and cognitive processes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/footer\u003e\u003cmain\u003e\n\u003ctable width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\" style=\"height: 115px; width: 100%;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 20px;\"\u003e\n\u003cth colspan=\"3\" style=\"font-size: 11pt; font-weight: bold; height: 20px;\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 19px;\"\u003eServing Size: 1 Lozenge\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 19px;\"\u003eServings Per Container: 30\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19px;\"\u003e\n\u003ctd colspan=\"2\" class=\"smalltext\" style=\"font-weight: bold; height: 19px;\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 19px;\" class=\"smalltext\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19px;\"\u003eVitamin B12\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 19px;\" align=\"right\"\u003e5000 mcg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 19px;\" align=\"right\"\u003e208333%\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19px;\"\u003e  Methylcobalamin\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 19px;\" align=\"right\"\u003e1786 mcg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 19px;\" align=\"right\"\u003e74417%\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19px;\"\u003e  Dibencozide\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 19px;\" align=\"right\"\u003e1786 mcg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 19px;\" align=\"right\"\u003e74416%\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19px;\"\u003e  Cyanocobalamin\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 19px;\" align=\"right\"\u003e1071 mcg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 19px;\" align=\"right\"\u003e44625%\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19px;\"\u003e  Hydroxycobalamin\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 19px;\" align=\"right\"\u003e357 mcg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 19px;\" align=\"right\"\u003e14875%\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 19px;\"\u003e% Daily Values are based on a 2,000 calorie diet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eREV. 12.23\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eSorbitol, natural strawberry flavor, rice extract blend, natural color (grape skin extract), and silicon dioxide.\u003cstrong\u003e \u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDOES NOT CONTAIN:\u003c\/strong\u003e Dairy, egg, soy, wheat, gluten, fish, shellfish, tree nuts, peanuts.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e Take 1 lozenge daily, allow lozenge to fully dissolve under your tongue, then swallow, or as recommended by your healthcare professional.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNOTE:\u003c\/strong\u003e Natural color variation may occur. Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e Not intended for use if you are pregnant or nursing. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your healthcare professional before using this product.\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/main\u003e\n\u003cdiv class=\"summary\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOptimize B12 Status. \u003c\/strong\u003eProHealth’s Vitamin B12 was specifically formulated to reduce symptoms of age-related health decline associated with low vitamin b12 levels.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnique Combination: \u003c\/strong\u003eCompared to other supplement brands using isolated forms of vitamin b12 ProHealth’s Vitamin B12 contains four different forms of vitamin B12, each selected for their unique contributions to cellular health, energy metabolism, and overall longevity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Longevity","offers":[{"title":"Default Title","offer_id":43278331117668,"sku":"PH639","price":4.78,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH639_175CC_FRNT_600x600-REV1223.png?v=1753368561"},{"product_id":"prohealth-vitamin-b-12-5000-mcg-120-lozenges-ph650","title":"Vitamin B-12 - 5000 mcg, 120 lozenges","description":"\u003cdetails\u003e\n\u003ch2\u003eBenefits:\u003c\/h2\u003e\n\u003cp\u003eIntroducing ProHealth Longevity's Vitamin B12, a unique combination crafted to harness the synergistic benefits of multiple forms of Vitamin B12. This innovative formula incorporates methylcobalamin, dibencozide, cyanocobalamin, and hydroxycobalamin, each selected for their unique contributions to cellular health, energy metabolism, and overall longevity. While many B12 supplements focus solely on one form of B12, ProHealth Longevity's Vitamin B12 embraces a comprehensive approach, recognizing the diverse roles and benefits offered by each variant. From supporting brain function to enhancing energy levels and combating age-related declines, our formula is designed to optimize B12 status and promote vitality at every stage of life.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePlays a crucial role in maintaining cellular integrity by aiding in DNA synthesis and repair\u003c\/li\u003e\n\u003cli\u003eActs as a cofactor in the conversion of carbohydrates, fats, and proteins into usable energy\u003c\/li\u003e\n\u003cli\u003eSupports healthy brain aging by aiding in the regeneration of myelin, the protective sheath around nerve fibers\u003c\/li\u003e\n\u003cli\u003eProvides mood support by serving as a cofactor in the synthesis of neurotransmitters\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca style=\"color: #0000ff;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PRHCX-1902_Vitamin_B-12_2311013.pdf\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eResearch-Supported Benefits:\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eEnhances cellular health.\u003c\/strong\u003e Vitamin B12 is a pivotal player in the synthesis and repair of DNA, critical processes that safeguard cellular integrity. Research has linked Vitamin B12 deficiency to disruptions in DNA synthesis and repair mechanisms, underscoring its importance in maintaining genetic stability. (1) Vitamin B12 offers further cellular protection by supporting telomere maintenance, the protective caps at the ends of chromosomes. Telomeres play a vital role in preserving DNA integrity during cell division, and their maintenance is closely linked to longevity and overall health. By supporting telomere integrity and DNA repair mechanisms, Vitamin B12 contributes to enhanced cellular resilience and longevity, offering comprehensive support for optimal aging.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHeathy heart aging:\u003c\/strong\u003e Vitamin B12 aids in the reduction of homocysteine levels, an amino acid implicated in various forms of DNA damage, including DNA strand breaks. Elevated homocysteine is associated with accelerated cardiovascular aging and increased risk of cardiovascular events. (2) Research shows that increasing vitamin B12 intake may reduce homocysteine levels up to 7%. (3)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePromotes energy production.\u003c\/strong\u003e Vitamin B12 is indispensable for sustaining energy levels, with its deficiency linked to reduced energy production in the body. Through its involvement in synthesizing SAMe, a vital methyl donor nutrient, Vitamin B12 supports mitochondrial function and the generation of ATP, the primary energy currency of cells. As we age, ATP production tends to decline, exacerbated by decreasing levels of Vitamin B12. This decline can lead to age-related fatigue and diminished stamina. Supplementation with Vitamin B12 may offer a solution by replenishing stores and potentially mitigating the decline in ATP production associated with aging.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePromotes Cognitive Health.\u003c\/strong\u003e Vitamin B12 plays a crucial role in maintaining cognitive function, and its deficiency is strongly associated with cognitive decline and memory impairment. (4) Its diverse functions in methylation, neurotransmitter synthesis, and mitochondrial activity are essential for optimal brain health. Notably, Vitamin B12 shows promise in mitigating age-related neurodegeneration by regulating inflammatory processes and protecting against the formation of amyloid beta (Aβ) plaque. (5) Supplementation with Vitamin B12 has potential to alleviate symptoms linked to accelerated brain aging and support overall cognitive well-being.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Mood.\u003c\/strong\u003e Vitamin B12 plays a vital role in the synthesis of essential mood-regulating neurotransmitters, including serotonin and dopamine. Serotonin, known as the \"feel-good\" neurotransmitter, is synthesized from the amino acid tryptophan in a process facilitated by SAMe, which in turn relies on sufficient levels of Vitamin B12 for optimal function. Similarly, dopamine, a neurotransmitter linked to reward, pleasure, and motivation, also depends on Vitamin B12 for its synthesis. Scientific studies have demonstrated that deficiency in Vitamin B12 correlates with mood dysregulation, contributing to symptoms such as irritability and personality changes. (6)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Alzoubi KH, Bayraktar E, Khabour O, Al-Azzam SI. Vitamin B12 protects against DNA damage induced by hydrochlorothiazide. Saudi Pharm J. 2018;26(6):786-789. doi:10.1016\/j.jsps.2018.04.005 \u003cbr\u003e\u003cbr\u003e2. Yan Y, Yin Y, Feng X, et al. Homocysteine aggravates DNA damage by impairing the FA\/Brca1 Pathway in NE4C murine neural stem cells. Int J Med Sci. 2020;17(16):2477-2486. Published 2020 Sep 9. doi:10.7150\/ijms.49246 \u003cbr\u003e\u003cbr\u003e3. Maruyama K, S Eshak E, Kinuta M, et al. Association between vitamin B group supplementation with changes in % flow-mediated dilatation and plasma homocysteine levels: a randomized controlled trial. J Clin Biochem Nutr. 2019;64(3):243-249. doi:10.3164\/jcbn.17-56 \u003cbr\u003e\u003cbr\u003e4. Jatoi S, Hafeez A, Riaz SU, Ali A, Ghauri MI, Zehra M. Low Vitamin B12 Levels: An Underestimated Cause Of Minimal Cognitive Impairment And Dementia. Cureus. 2020;12(2):e6976. Published 2020 Feb 13. doi:10.7759\/cureus.6976 \u003cbr\u003e\u003cbr\u003e5. Lam AB, Kervin K, Tanis JE. Vitamin B12 impacts amyloid beta-induced proteotoxicity by regulating the methionine\/S-adenosylmethionine cycle. Cell Rep. 2021;36(13):109753. doi:10.1016\/j.celrep.2021.109753 \u003cbr\u003e\u003cbr\u003e6. Sangle P, Sandhu O, Aftab Z, Anthony AT, Khan S. Vitamin B12 Supplementation: Preventing Onset and Improving Prognosis of Depre**ion. Cureus. 2020;12(10):e11169. Published 2020 Oct 26. doi:10.7759\/cureus.11169\u003c\/p\u003e\n\u003c\/details\u003e\u003cfooter\u003e\n\u003cul\u003e\n\u003cli\u003eWhen taken as a supplement, Vitamin B12 is released in the stomach and binds to intrinsic factor, a protein produced by the stomach lining.\u003c\/li\u003e\n\u003cli\u003eThe Vitamin B12-intrinsic factor complex travels to the small intestine, where it is absorbed into the bloodstream through specialized receptors in the intestinal lining.\u003c\/li\u003e\n\u003cli\u003eOnce in the bloodstream, Vitamin B12 is transported to various tissues and cells throughout the body, where it exerts its functions.\u003c\/li\u003e\n\u003cli\u003eVitamin B12 plays a crucial role in energy metabolism as a cofactor for the enzyme methionine synthase, which helps convert homocysteine to methionine. Methionine serves as a precursor for S-adenosylmethionine (SAMe), a key methyl donor in cellular reactions.\u003c\/li\u003e\n\u003cli\u003eSAMe participates in methylation reactions essential for ATP synthesis, the primary energy currency of cells, thus contributing to overall energy production and vitality.\u003c\/li\u003e\n\u003cli\u003eVitamin B12 helps maintain mitochondrial health and facilitates neurotransmitter synthesis, promoting youthful cognitive functioning and reducing the risk of age-related cognitive decline.\u003c\/li\u003e\n\u003cli\u003eVitamin B12 is crucial for brain health and cognitive function, as it supports mitochondrial function and neurotransmitter synthesis. Mitochondria in brain cells require Vitamin B12 for energy production, which is essential for maintaining neuronal activity and cognitive processes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/footer\u003e\u003cmain\u003e\n\u003ctable width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\" style=\"height: 115px; width: 100%;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 20px;\"\u003e\n\u003cth colspan=\"3\" style=\"font-size: 11pt; font-weight: bold; height: 20px;\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 19px;\"\u003eServing Size: 1 Lozenge\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 19px;\"\u003eServings Per Container: 120\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19px;\"\u003e\n\u003ctd colspan=\"2\" class=\"smalltext\" style=\"font-weight: bold; height: 19px;\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 19px;\" class=\"smalltext\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19px;\"\u003eVitamin B12\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 19px;\" align=\"right\"\u003e5000 mcg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 19px;\" align=\"right\"\u003e208333%\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19px;\"\u003e  Methylcobalamin\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 19px;\" align=\"right\"\u003e1786 mcg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 19px;\" align=\"right\"\u003e74417%\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19px;\"\u003e  Dibencozide\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 19px;\" align=\"right\"\u003e1786 mcg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 19px;\" align=\"right\"\u003e74416%\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19px;\"\u003e  Cyanocobalamin\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 19px;\" align=\"right\"\u003e1071 mcg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 19px;\" align=\"right\"\u003e44625%\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19px;\"\u003e  Hydroxycobalamin\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 19px;\" align=\"right\"\u003e357 mcg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; height: 19px;\" align=\"right\"\u003e14875%\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 19px;\"\u003e% Daily Values are based on a 2,000 calorie diet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eREV. 12.23\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eSorbitol, natural strawberry flavor, rice extract blend, natural color (grape skin extract), and silicon dioxide.\u003cstrong\u003e \u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDOES NOT CONTAIN:\u003c\/strong\u003e Dairy, egg, soy, wheat, gluten, fish, shellfish, tree nuts, peanuts.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e Take 1 lozenge daily, allow lozenge to fully dissolve under your tongue, then swallow, or as recommended by your healthcare professional.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNOTE:\u003c\/strong\u003e Natural color variation may occur. Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e Not intended for use if you are pregnant or nursing. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your healthcare professional before using this product.\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/main\u003e\n\u003cdiv class=\"summary\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOptimize B12 Status. \u003c\/strong\u003eProHealth’s Vitamin B12 was specifically formulated to reduce symptoms of age-related health decline associated with low vitamin b12 levels.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnique Combination: \u003c\/strong\u003eCompared to other supplement brands using isolated forms of vitamin b12 ProHealth’s Vitamin B12 contains four different forms of vitamin B12, each selected for their unique contributions to cellular health, energy metabolism, and overall longevity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Longevity","offers":[{"title":"Default Title","offer_id":43285241462884,"sku":"PH650","price":15.98,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH650_100mL_FRNT_600x600_f0fb47be-5ab7-4b7d-9df7-3dd5b69df84f.png?v=1738178578"},{"product_id":"prohealth-pure-melatonin-1-mg-120-capsules-ph691","title":"Pure Melatonin - 1 mg, 120 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\" data-mce-style=\"font-size: 1.1em;\"\u003eBalance Your Biological Clock with Pure, Low-Dose Melatonin* \u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBoost melatonin levels*\u003csup\u003e1\u003c\/sup\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003ePromote a healthy sleep cycle*\u003csup\u003e2\u003c\/sup\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eHelp combat oxidative stress*\u003csup\u003e3\u003c\/sup\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eMaintain cellular health and function*\u003csup\u003e4\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eSupport skin health*\u003csup\u003e5\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/7-1-2026_PH691_REVALIDATION_TESTING_EXP_DATE_Pure_Melatonin_1_mg_120_ct__A24I034_2.pdf?v=1793029730\" rel=\"noopener noreferrer\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eExtensively Researched:\u003c\/strong\u003e Backed by thousands of studies, melatonin plays a key role in a wide range of physiological processes, offering benefits beyond sleep to support overall health, well-being, and longevity.* \u003csup\u003e4-5\u003c\/sup\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOptimal Dosing:\u003c\/strong\u003e Recent studies suggest that lower doses of melatonin (closer to normal biological levels) may better support circadian rhythm health and optimize biological function, without disrupting natural hormone balance.*\u003csup\u003e5\u003c\/sup\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrecision Manufacturing:\u003c\/strong\u003e A study of 31 retail melatonin supplements showed content variation between -83% to +478% of the labeled amount.\u003csup\u003e6\u003c\/sup\u003e ProHealth’s Pure Melatonin ensures consistency, with accurate dosing every time.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTrusted Quality Since 1988:\u003c\/strong\u003e USA manufactured, 3rd-party lab tested, GMP certified for your peace of mind.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\" data-mce-style=\"font-size: 1.1em;\"\u003eWhat Makes Ours Better?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eLongevity Focused:\u003c\/strong\u003e We leverage cutting-edge advancements in aging research to formulate products that address the fundamental causes of aging.*\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTriple Lab Tested:\u003c\/strong\u003e Every product is tested three times by independent 3rd-party labs to ensure we meet the highest standards.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eComplete Transparency:\u003c\/strong\u003e In an industry flooded with fake supplements, we stand apart by publishing our 3rd-party lab test results. We’re committed to showing you exactly what’s in every bottle, so you can feel confident in what you’re putting into your body.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUSA Manufacturing Excellence:\u003c\/strong\u003e Made in FDA-regulated, GMP-certified facilities in the USA for the highest quality and safety standards.*\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e100-Day Risk-Free Guarantee:\u003c\/strong\u003e We stand behind our products. Not satisfied? Reach out to our Santa Barbara, CA office for a full refund within 100 days – no hassle, no questions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAt ProHealth, we understand that your longevity journey deserves a foundation built on quality and integrity. That’s why we proudly offer Pure Melatonin, a premium source of melatonin delivered in a safe and effective therapeutic dose that aligns with the body’s own physiological needs. While doses \u003cspan class=\"TextRun SCXW24300739 BCX2\" lang=\"EN-US\" style=\"background-color: transparent; font-size: 12pt; line-height: 22.0083px; font-family: Aptos, 'Aptos_EmbeddedFont', 'Aptos_MSFontService', sans-serif;\" data-contrast=\"auto\" xml:lang=\"EN-US\"\u003e\u003cspan class=\"NormalTextRun SCXW24300739 BCX2\"\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"TextRun SCXW24300739 BCX2\" lang=\"EN-US\" style=\"background-color: transparent; font-size: 12pt; line-height: 22.0083px; font-family: 'Symbol', 'Symbol_EmbeddedFont', 'Symbol_MSFontService', sans-serif;\" data-contrast=\"auto\" xml:lang=\"EN-US\"\u003e\u003cspan class=\"NormalTextRun SCXW24300739 BCX2\"\u003e³\u003c\/span\u003e\u003c\/span\u003e 5 mg are the trend, long-term safety studies are lacking and too much melatonin can negatively disrupt the circadian rhythm. ProHealth’s Pure Melatonin allows customers to begin with a “physiologically aligned” dose and increase as needed.*\u003csup\u003e5\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003ePure Melatonin helps boost melatonin levels to maintain a normal sleep-wake cycle which often becomes challenged as a natural part of aging. Quality sleep is paramount for optimum health and quality of life. As a potent free radical scavenger, melatonin also protects the mitochondria and helps optimize cellular health and functions.  While melatonin helps the body repair and replenish during the nighttime, it also protects the skin from environmental stressors during the daytime.*\u003csup\u003e1,3,5\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\" data-mce-style=\"font-size: 1.1em;\"\u003eBalance Your Biological Clock with Pure, Low-Dose Melatonin*\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePromote a Healthy Sleep Cycle*\u003csup\u003e2\u003c\/sup\u003e\u003c\/strong\u003e\u003cbr\u003eMelatonin is naturally produced by the pineal gland in the brain. It is estimated that the body produces between 0.1 mg and 0.9 mg melatonin daily. However, beginning in our 20’s to 50’s, the body’s melatonin levels begin to decline. The most noticeable symptom from lower melatonin production is poor sleep. Therefore, supplementing with a minimally effective therapeutic dose that aligns with the body’s own physiological needs can help boost melatonin levels to maintain a normal sleep-wake cycle. Clinical studies have demonstrated that melatonin supplementation helps to promote sleep onset and overall sleep quality.*\u003csup\u003e2\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProtect Cells from Oxidative Stress*\u003csup\u003e3\u003c\/sup\u003e\u003c\/strong\u003e\u003cbr\u003eMelatonin is a potent free radical scavenger, even more so than glutathione and vitamins C and E. This is because melatonin contributes to a unique “antioxidant cascade” mechanism which allows numerous metabolites to sequentially scavenge multiple reactive oxygen species. Through this mechanism, melatonin scavenges up to 10 free radicals compared to two or three with other common antioxidant ingredients.*\u003csup\u003e3\u003cbr\u003e\u003cbr\u003e\u003c\/sup\u003eMelatonin is particularly concentrated within the mitochondria of our cells where it directly scavenges free radicals and helps to maintain healthy levels of antioxidant defense enzymes. This feature makes melatonin vital for maintaining healthy mitochondria and overall cellular health and functions.*\u003csup\u003e3-4\u003cbr\u003e\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupport Skin Health*\u003csup\u003e5\u003c\/sup\u003e\u003c\/strong\u003e\u003cbr\u003eA unique and lesser-known feature of melatonin is its beneficial effects on the skin, the body’s largest organ. Melatonin naturally resides in the skin and its potent free radical scavenging properties help protect the skin from the environmental stressors that accompany everyday living. Therefore, melatonin may offer a beauty-from-within antidote for maintaining healthy, younger-looking skin.*\u003csup\u003e5\u003cbr\u003e\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFeel the Difference with ProHealth’s Pure Melatonin\u003c\/strong\u003e\u003cbr\u003eExperience the unmatched quality of a melatonin supplement that stands out for its purity and scientific backing delivered in a safe and effective therapeutic dose that aligns with the body’s own physiological needs. Don’t just slow the signs of aging—revitalize your health at the cellular level with ProHealth’s Pure Melatonin.*\u003csup\u003e4\u003cbr\u003e\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOrder now and join the 200,000+ people who trust ProHealth\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\" data-mce-style=\"font-size: 1.1em;\"\u003eIngredients:\u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMelatonin:\u003c\/strong\u003e A nature-identical compound that mirrors the body's melatonin, supporting key functions related to sleep and circadian rhythm regulation.*\u003csup\u003e5\u003c\/sup\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003csup\u003e1\u003c\/sup\u003e Zhdanova IV et al. \u003cem\u003eJ Clin Endocrinol Metab\u003c\/em\u003e. 2001;86(10):4727-4730. \u003cbr\u003e\u003csup\u003e2\u003c\/sup\u003e Sletten TL et al. \u003cem\u003ePLOS Med.\u003c\/em\u003e 2018;15(6):e1002587. \u003cbr\u003e\u003csup\u003e3\u003c\/sup\u003e Kruk J et al. \u003cem\u003eJ Physiol Sci.\u003c\/em\u003e 2021;71(1):27. \u003cbr\u003e\u003csup\u003e4\u003c\/sup\u003e Reiter RJ. \u003cem\u003eExp Gerontol.\u003c\/em\u003e 1995;30(3-4):199-212.  \u003cbr\u003e\u003csup\u003e5\u003c\/sup\u003e Minich DM et al. \u003cem\u003eNutrients.\u003c\/em\u003e 2022;14(19):3934. \u003cbr\u003e\u003csup\u003e6\u003c\/sup\u003e Li J et al. \u003cem\u003eJAMA.\u003c\/em\u003e 2022;327(5):483-485.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\" style=\"height: 216.533px;\" data-mce-style=\"height: 216.533px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 20.5333px;\" data-mce-style=\"height: 20.5333px;\"\u003e\n\u003cth colspan=\"3\" style=\"font-size: 11pt; font-weight: bold;\" align=\"left\" data-mce-style=\"font-size: 11pt; font-weight: bold;\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\" data-mce-style=\"height: 19.6px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 19.6px;\" data-mce-style=\"height: 19.6px;\"\u003eServing Size: 1 Capsule\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\" data-mce-style=\"height: 19.6px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 19.6px;\" data-mce-style=\"height: 19.6px;\"\u003eServings Per Container: 120\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\" data-mce-style=\"height: 19.6px;\"\u003e\n\u003ctd colspan=\"2\" class=\"smalltext\" style=\"font-weight: bold;\" data-mce-style=\"font-weight: bold;\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\" data-mce-style=\"white-space: nowrap;\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\" data-mce-style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19.6px;\" data-mce-style=\"height: 19.6px;\"\u003eMelatonin\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\" data-mce-style=\"white-space: nowrap;\"\u003e1 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\" data-mce-style=\"white-space: nowrap;\"\u003e†\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\" data-mce-style=\"height: 19.6px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 19.6px;\" data-mce-style=\"height: 19.6px;\"\u003e† Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eREV.09.24\u003c\/p\u003e\n\u003cp\u003eNu-FLOW® is a registered trademark of Ribus Inc.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eVegetable cellulose (capsule), rice our, microcrystalline cellulose and Nu-FLOW® (rice hulls).\u003cstrong\u003e \u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e Take one (1) capsule 30 to 60 minutes before bedtime, or as recommended by a healthcare practitioner. Melatonin is naturally produced in the pineal gland at night and should be taken at bedtime for best results.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e For use by healthy adults only. Do not drink alcohol, or operate a vehicle or heavy machinery after taking this product. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e. Store in a cool and dry place after opening.\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Longevity","offers":[{"title":"Default Title","offer_id":51691591172462,"sku":"PH691","price":4.98,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0206\/3076\/5668\/files\/PH691_175ML_FRNT_600x600_0924_00f112cd-c433-42af-8ab7-0c8243c5c048.png?v=1738185899"}],"url":"https:\/\/www.prohealth.com\/en-ae\/collections\/upcoming-discontinued-products.oembed","provider":"ProHealth.com","version":"1.0","type":"link"}