A blinded, controlled evaluation of anxiety & depressive symptoms in patients with fibromyalgia (FM), as measured by standardized psychometric interview scales

The objective of the study was to evaluate the presence of

psychopathology in fibromyalgia patients compared with a

control group of other rheumatologic patients with pain.

Forty-nine fibromyalgia patients and 33 control patients were

interviewed blinded, using standardized psychometric scales.

Pain was scored on a visual analogue scale. Fibromyalgia

patients scored significantly higher than the controls on the

Bech-Rafaelsen Melancholia Scale, the Atypical Depression

Scale and the Hamilton Anxiety Rating Scale. On the Newcastle

Depression Scale there was no difference. In both groups a

correlation was found between pain score and psychometric


The fibromyalgia patients scored significantly higher on

pain than the controls. After correcting for this difference,

the fibromyalgia patients still scored higher on anxiety and


Krag NJ, Norregaard J, Larsen JK, Danneskiold-Samsoe B

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