OBJECTIVE: To establish a model for the detection of specific
factors associated with the severity of symptoms and the
impact of fibromyalgia (FM).
METHODS: We evaluated 332 consecutive new patients with
FM for factors that may be associated with disease severity,
assessed by patient global assessment, and function, evaluated
by the Fibromyalgia Impact Questionnaire (FIQ). Fifteen potential
explanatory factors were evaluated in a multiple linear regression
model on data taken from an extensive group of standardized
RESULTS: Of the 15 factors, pain levels, self-assessed
inability to work, psychological distress, pending litigation,
helplessness, level of education, and coping ability had a
significant association with patients' global assessment and
with scores on the total FIQ as well as on the activities of
daily living subcomponent of the FIQ.
CONCLUSION: Disease related factors such as pain and
psychological factors such as work status, helplessness,
education, and coping ability had an independent and significant
relationship to FM symptom severity and function.
Goldenberg DL, Mossey CJ, Schmid CH