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Abnormal responses to electrocutaneous stimulation in Fibromyalgia (FM)

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OBJECTIVE. As disturbed nociception may be relevant to the

pathogenesis of fibromyalgia, nonnoxious electrocutaneous

stimulation was used as a tool to investigate nociceptive

status.

METHODS. Perception threshold and pain tolerance were

studied in the upper limbs of 10 patients with fibromyalgia

and 10 healthy volunteers.

RESULTS. Perception threshold did

not differ between the groups but the marked reduction in pain

tolerance found in patients with fibromyalgia was accompanied

by spread and persistence of dysesthesiae.

CONCLUSION. The

upper limbs of patients with fibromyalgia resembled regions of

secondary hyperalgesia, which may imply that perturbation of

central nociceptive mechanisms is involved in the pathogenesis

of this syndrome.

Arroyo JF, Cohen ML

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