Clin Infect Dis. 2003 Aug 15;37(4):528-32. Epub 2003 Jul 30. Steere AC, Sikand VK, Schoen RT, Nowakowski J. Division of Rheumatology/Immunology, Tufts University School of Medicine, New England Medical Center, Boston, MA, USA. firstname.lastname@example.org
The natural history of asymptomatic seroconversion to Borrelia burgdorferi has been unclear. We report here, on the basis of a post hoc assessment, the frequency and outcome of asymptomatic seroconversion to B. burgdorferi in participants of a large Lyme disease vaccine trial. We show that infection with B. burgdorferi may be asymptomatic but that asymptomatic infection is unusual in the United States.
Randomized Controlled Trial
PMID: 12905137 [PubMed – indexed for MEDLINE]