Abstract: Asymptomatic infection with Borrelia burgdorferi

Clin Infect Dis. 2003 Aug 15;37(4):528-32. Epub 2003 Jul 30.  Steere AC, Sikand VK, Schoen RT, Nowakowski J.  Division of Rheumatology/Immunology, Tufts University School of Medicine, New England Medical Center, Boston, MA, USA. asteere@partners.org

The natural history of asymptomatic seroconversion to Borrelia burgdorferi has been unclear. We report here, on the basis of a post hoc assessment, the frequency and outcome of asymptomatic seroconversion to B. burgdorferi in participants of a large Lyme disease vaccine trial. We show that infection with B. burgdorferi may be asymptomatic but that asymptomatic infection is unusual in the United States.

Publication Types:
Clinical Trial
Multicenter Study
Randomized Controlled Trial

PMID: 12905137 [PubMed – indexed for MEDLINE]

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